J2260 NDC Crosswalk, Billing Units, ASP Payment & Medicare Reimbursement

📋 J2260 summary

J2260 is a HCPCS Level II J-code used to bill milrinone lactate, 5 mg, billed per 5 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J2260: Milrinone In, Milrinone Lactate, Milrinone Lactate In Dextrose

Code J2260 Billing unit 5 MG Payment limit $1.098/unit NDC-Crosswalk 34 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ2260

DescriptorInjection, milrinone lactate, 5 mg

Billing unit5 MG

Payment limit / unit$1.098

Est. ASP / unit$1.036 est.

Mapped NDCs34

Data periodQ3 2026

Last updated2026-08-20

💊 About Milrinone DRUG GUIDE

Milrinone Lactate Injection and Milrinone Lactate in 5% Dextrose Injection are indicated for the short-term intravenous treatment of acute decompensated heart failure — a sudden or rapidly worsening episode of heart failure that requires immediate, in-hospital care.This medication is given only in a monitored hospital setting.

It is not intended for long-term or home use.

Most clinical experience has been in patients who were also taking digoxin and diuretics (water pills).

Read the full Milrinone drug guide →

Clinical overview from our editorial drug guide for Milrinone. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).

Medicare payment limit / unit

$1.098

Est. ASP / unit

$1.036 est.

Est. after 2% sequester

$1.076

HCPCS dosage

5 MG

The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.

Full HCPCS code details (official CMS record)

Long descriptionInjection, milrinone lactate, 5 mg

CoverageD — Special coverage instructions apply

Pricing indicator51 — Drug — priced under the ASP methodology

Type of service1 — Medical care

BETOS-2O1E

ASC payment group—

Action codeN — No maintenance this year

Effective date2018-01-01

Date added1986-01-01

Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J2260 = 5 mg. Enter a regimen to convert dose → billing units and project a full course.

Dose per administration (mg) Frequency — every days Number of doses NDC / package billed (optional)

Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J2260 WITH EST. MEDICARE PAY

34 NDCs map to J2260. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($1.098/unit) × that package's bill units.

NDC (11-digit)	Drug	Labeler	Package	Strength	Bill units	Est. pay / pkg	NADAC / unit	Status	Source
00143-9326-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	10 VIAL in 1 CARTON (0143-9326-10) / 20 m...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
00143-9373-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	10 VIAL in 1 CARTON (0143-9373-10) / 10 m...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
00143-9374-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	10 VIAL in 1 CARTON (0143-9374-10) / 20 m...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
00143-9708-01	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	50 mL in 1 BOX (0143-9708-01)	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
00143-9709-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	10 VIAL in 1 BOX (0143-9709-10) / 20 mL i...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
00143-9710-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Hikma	10 VIAL in 1 BOX (0143-9710-10) / 10 mL i...	1 mg/mL	20	$21.96	—	● Active	CMS ASP
00143-9718-10	Milrinone Lactate in Dextrose 200 ug/mL INJECTION, SOLUTION	Hikma	10 CONTAINER in 1 PACKAGE (0143-9718-10)...	200 ug/mL	80	$87.84	—	● Active	CMS + PDAC
00143-9719-10	Milrinone Lactate in Dextrose 200 ug/mL INJECTION, SOLUTION	Hikma	10 CONTAINER in 1 PACKAGE (0143-9719-10)...	200 ug/mL	40	$43.92	—	● Active	CMS + PDAC
00338-6010-48	Milrinone Lactate in Dextrose .2 mg/mL INJECTION, SOLUTION	Baxter	10 BAG in 1 CARTON (0338-6010-48) / 100 m...	.2 mg/mL	4	$4.39	—	● Active	CMS + PDAC
00338-6011-37	Milrinone Lactate in Dextrose .2 mg/mL INJECTION, SOLUTION	Baxter	10 BAG in 1 CARTON (0338-6011-37) / 200 m...	.2 mg/mL	8	$8.78	—	● Active	CMS + PDAC
00409-0212-01	MILRINONE LACTATE 1 mg/mL INJECTION, SOLUTION	Hospira,	10 VIAL, SINGLE-DOSE in 1 CARTON (0409-021...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
00409-0212-02	MILRINONE LACTATE 1 mg/mL INJECTION, SOLUTION	Hospira,	10 VIAL, SINGLE-DOSE in 1 CARTON (0409-021...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
00409-0212-03	MILRINONE LACTATE 1 mg/mL INJECTION, SOLUTION	Hospira,	1 VIAL, SINGLE-DOSE in 1 CARTON (0409-0212...	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
00409-2045-10	Milrinone Lactate in Dextrose .2 mg/mL INJECTION, SOLUTION	Hospira,	10 POUCH in 1 CARTON (0409-2045-10) / 1 B...	.2 mg/mL	40	$43.92	—	● Active	CMS + PDAC
25021-0313-82	Milrinone Lactate in Dextrose .2 mg/mL INJECTION, SOLUTION	Sagent	10 BAG in 1 CARTON (25021-313-82) / 100 m...	.2 mg/mL	40	$43.92	—	● Active	CMS + PDAC
25021-0313-87	Milrinone Lactate in Dextrose .2 mg/mL INJECTION, SOLUTION	Sagent	10 BAG in 1 CARTON (25021-313-87) / 200 m...	.2 mg/mL	80	$87.84	—	● Active	CMS ASP
55150-0287-10	Milrinone Lactate .2 mg/mL INJECTION, SOLUTION	Eugia	10 POUCH in 1 CARTON (55150-287-10) / 1 B...	.2 mg/mL	40	$43.92	—	● Active	CMS + PDAC
55150-0288-10	Milrinone Lactate .2 mg/mL INJECTION, SOLUTION	Eugia	10 POUCH in 1 CARTON (55150-288-10) / 1 B...	.2 mg/mL	80	$87.84	—	● Active	CMS ASP
63323-0617-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Fresenius	10 VIAL, SINGLE-DOSE in 1 TRAY (63323-617-...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
63323-0617-20	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Fresenius	10 VIAL, SINGLE-DOSE in 1 TRAY (63323-617-...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
63323-0617-50	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Fresenius	1 VIAL, SINGLE-DOSE in 1 CARTON (63323-617...	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
65145-0121-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Caplin	10 VIAL in 1 CARTON (65145-121-10) / 20 m...	1 mg/mL	40	$43.92	—	● Active	CMS ASP
65145-0122-01	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Caplin	1 VIAL in 1 CARTON (65145-122-01) / 50 mL...	1 mg/mL	10	$10.98	—	● Active	CMS ASP
70069-0807-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Somerset	10 VIAL in 1 CARTON (70069-807-10) / 10 m...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
70069-0808-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Somerset	10 VIAL in 1 CARTON (70069-808-10) / 20 m...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
70069-0809-01	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Somerset	1 VIAL in 1 CARTON (70069-809-01) / 50 mL...	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
71288-0200-11	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Meitheal	10 VIAL, SINGLE-DOSE in 1 CARTON (71288-20...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
71288-0200-21	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Meitheal	10 VIAL, SINGLE-DOSE in 1 CARTON (71288-20...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
71288-0200-50	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Meitheal	1 VIAL, SINGLE-DOSE in 1 CARTON (71288-200...	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
72485-0501-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Armas	10 VIAL in 1 CARTON (72485-501-10) / 10 m...	1 mg/mL	20	$21.96	—	● Active	CMS + PDAC
72485-0502-10	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Armas	10 VIAL in 1 CARTON (72485-502-10) / 20 m...	1 mg/mL	40	$43.92	—	● Active	CMS + PDAC
72485-0503-01	Milrinone Lactate 1 mg/mL INJECTION, SOLUTION	Armas	1 VIAL in 1 CARTON (72485-503-01) / 50 mL...	1 mg/mL	10	$10.98	—	● Active	CMS + PDAC
00409-2776-02	MILRINONE LACTATE (IN 5% DEXTROSE,10X200ML) 5%-20 MG/100 ML	Unknown	—	—	0.04	$0.04	—	—	PDAC
00409-2776-23	DEXTROSE/MILRINONE LACTATE (10X100ML,LATEX-FREE) 5%-20 MG/100 ML	Unknown	—	—	0.04	$0.04	—	—	PDAC

NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period

Total Part B spend

$551.1K

Claims

7,266

Beneficiaries

823

Spend / beneficiary

$669.65

Spend / claim

$75.85

Trend by period

Where J2260 ranks among Part B drugs · 2026 (Q1) · neighbors ±5

Total spending — #432 of 824

#427 MYLOTARG J9203 $570.9K #428 GRAFIX PLUS, PER SQ... Q4304 $566.2K #429 CAPECITABINE* J8522 $562.7K #430 OMNIPAQUE Q9965 $559.4K #431 PRIALT J2278 $553.3K #432 MILRINONE IN 5% DEXT... J2260 $551.1K #433 RAPAMUNE* J7520 $539.9K #434 CORIFACT J7180 $532.3K #435 CARNITOR* J1955 $526.4K #436 ASTAGRAF XL J7508 $524K #437 HYMPAVZI PEN J7172 $521.5K

Total claims — #187 of 824

#182 DIPRIVAN* J2704 7,494 #183 BENLYSTA J0490 7,491 #184 TDVAX* 90714 7,419 #185 GLUCAGON EMERGENCY K... J1611 7,378 #186 ALYMSYS Q5126 7,293 #187 MILRINONE IN 5% DEXT... J2260 7,266 #188 DOCETAXEL J9171 7,049 #189 GAZYVA J9301 7,018 #190 NIVESTYM Q5110 6,956 #191 OGIVRI Q5114 6,950 #192 VYVGART HYTRULO J9334 6,883

Full breakdown by period (2)

Period	Total spend	Beneficiaries	Claims	$/beneficiary	$/claim
2026 (Q1)	$551.1K	823	7,266	$669.65	$75.85
2025 (Q1-Q4)	$2.77M	1,690	33,965	$1,636.84	$81.44

Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.

Allowed charges

$2.81M

Medicare paid

$2.19M

Submitted services

2,440,265

Denial rate

14.6%

Allowed / service

$1.35

Submitted charges

$74.23M

Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

📊 What bills under J2260

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient

Milrinone Lactate 13

MILRINONE LACTATE 4

Milrinone Lactate in Dextrose 3

Milrinone Lactate in 5% Dextrose 1

NDC products by labeler

Hikma Pharmaceuticals USA Inc. 7

Somerset Therapeutics, LLC 3

Armas Pharmaceuticals Inc. 3

Baxter Healthcare Corporation 2

Hospira, Inc. 2

Sagent Pharmaceuticals 1

Eugia US LLC 1

Fresenius Kabi USA, LLC 1

🔗 Related NDC directory pages

🧪 All Milrinone Lactate NDCsIngredient 🧪 All Milrinone Lactate NDCsIngredient 🧪 All Milrinone Lactate In Dextrose NDCsIngredient 🧪 All Milrinone Lactate In 5% Dextrose NDCsIngredient 🏭 All Hikma labeler NDCsLabeler 00143 🏭 All Somerset labeler NDCsLabeler 70069 🏭 All Armas labeler NDCsLabeler 72485 🏭 All Baxter labeler NDCsLabeler 00338 📚 All Phosphodiesterase 3 Inhibitor NDCsDrug class

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.

HCPCS code & descriptor

CMS HCPCS Level II code file

Loaded

Payment limit & billing unit

CMS Medicare Part B ASP Pricing File (quarterly)

Q3 2026 · as of 2026-08-20

NDC ↔ HCPCS crosswalk

CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)

34 NDCs mapped

NADAC acquisition cost

CMS National Average Drug Acquisition Cost (weekly)

Not available for mapped NDCs

Utilization & spend

CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners

Latest data year 2026

Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J2260 billing FAQ

What is HCPCS code J2260?

J2260 is a HCPCS Level II J-code used to bill Injection, milrinone lactate, 5 mg under Medicare Part B and most medical (not pharmacy) benefits.

What is the billing unit for J2260?

One unit of J2260 represents 5 MG. Report the number of units equal to the dose administered divided by 5 MG.

How many units of J2260 should I bill?

Divide the dose administered by the code's unit size (5 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.

How much does Medicare pay for J2260?

The Medicare Part B payment limit is $1.098 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $1.076 per unit. Payment limits are revised quarterly.

Which NDCs bill under J2260?

34 NDCs currently map to J2260 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.

Does a crosswalk mean J2260 is covered?

No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.

J2260 – Injection, milrinone lactate, 5 mg · NDC Crosswalk & Billing Units