J7508
J7508 – Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 3 NDCs crosswalked per 0.1 MG $0.601/unit ASP+6%
📋 J7508 summary
J7508 is a HCPCS Level II J-code used to bill Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg, billed per 0.1 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Brand names associated with J7508: Astagraf Xl
Code J7508
Billing unit 0.1 MG Payment limit $0.601/unit NDC-Crosswalk 3
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ7508
DescriptorTacrolimus, extended release, (astagraf xl), oral, 0.1 mg
Billing unit0.1 MG
Payment limit / unit$0.601
Est. ASP / unit$0.567 est.
Mapped NDCs3
Data periodQ3 2026
Last updated2026-08-20
💊 About Tacrolimus DRUG GUIDE
Tacrolimus is prescribed to help prevent your body from rejecting a transplanted organ.
It is used in adults who receive a kidney, liver, or heart transplant, and in children who receive a liver transplant.
It is always used alongside other anti-rejection medicines.Because tacrolimus works by dampening your immune system, it lowers the risk of your body attacking the new organ — but it also means you need to be watched closely for infections and other side effects throughout your treatment.
Clinical overview from our editorial drug guide for Tacrolimus. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.601
Est. ASP / unit
$0.567 est.
Est. after 2% sequester
$0.589
HCPCS dosage
0.1 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionTacrolimus, extended release, (astagraf xl), oral, 0.1 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date2018-01-01
Date added2014-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J7508 = 0.1 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J7508 LEAST EXPENSIVE FIRST
3 NDCs map to J7508. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.601/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00469-0647-73 | ASTAGRAF XL tacrolimus extended-release capsules .5 mg/1 CAPSULE, COATED, EXTENDED RELEASE | Astellas | 1 BOTTLE in 1 CARTON (0469-0647-73) / 30... | .5 mg/1 | 150 | $90.15 | $2.779 | ● Active | CMS + PDAC |
| 00469-0677-73 | ASTAGRAF XL tacrolimus extended-release capsules 1 mg/1 CAPSULE, COATED, EXTENDED RELEASE | Astellas | 1 BOTTLE in 1 CARTON (0469-0677-73) / 30... | 1 mg/1 | 300 | $180.30 | $5.709 | ● Active | CMS + PDAC |
| 00469-0687-73 | ASTAGRAF XL tacrolimus extended-release capsules 5 mg/1 CAPSULE, COATED, EXTENDED RELEASE | Astellas | 1 BOTTLE in 1 CARTON (0469-0687-73) / 30... | 5 mg/1 | 1,500 | $901.50 | $27.772 | ● Active | CMS + PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$524K
Claims
883
Beneficiaries
352
Spend / beneficiary
$1,488.68
Spend / claim
$593.45
Trend by period
Where J7508 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #436 of 824
#431
PRIALT J2278
$553.3K
#432
MILRINONE IN 5% DEXT... J2260
$551.1K
#433
RAPAMUNE* J7520
$539.9K
#434
CORIFACT J7180
$532.3K
#435
CARNITOR* J1955
$526.4K
#436
ASTAGRAF XL J7508
$524K
#437
HYMPAVZI PEN J7172
$521.5K
#438
AMNICORE PRO+, PER S... Q4299
$516.2K
#439
SIMULECT J0480
$512.7K
#440
IXEMPRA J9207
$507.9K
#441
SIGNIFOR LAR J2502
$497.3K
Total claims — #387 of 824
#382
BEOVU J0179
920
#383
CABENUVA J0741
920
#384
ORPHENADRINE CITRATE J2360
916
#385
PEMRYDI RTU J9324
903
#386
ENJAYMO J1302
892
#387
ASTAGRAF XL J7508
883
#388
PIPERACILLIN-TAZOBAC... J2543
873
#389
AMIKACIN SULFATE J0278
865
#390
LUMASON Q9950
846
#391
RELESE, PER SQ CM** Q4257
843
#392
LEUPROLIDE DEPOT* J1954
839
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $524K | 352 | 883 | $1,488.68 | $593.45 |
| 2025 (Q1-Q4) | $2.36M | 453 | 4,350 | $5,214.44 | $543.02 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$2.44M
Medicare paid
$1.87M
Submitted services
4,496,237
Denial rate
6.0%
Allowed / service
$0.58
Submitted charges
$3.41M
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J7508 is utilized
⏳
The geographic utilization map is building for this code — it aggregates millions of CMS Part B claim lines, then caches the result. Refresh in a moment; if it doesn’t appear, this code may have no reportable Part B utilization.
📊 What bills under J7508
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
3 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J7508 billing FAQ
What is HCPCS code J7508?
J7508 is a HCPCS Level II J-code used to bill Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J7508?
One unit of J7508 represents 0.1 MG. Report the number of units equal to the dose administered divided by 0.1 MG.
How many units of J7508 should I bill?
Divide the dose administered by the code's unit size (0.1 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J7508?
The Medicare Part B payment limit is $0.601 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.589 per unit. Payment limits are revised quarterly.
Which NDCs bill under J7508?
3 NDCs currently map to J7508 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J7508 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.