Acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydro... — RxCUI 1113705
RxNorm drug concept · Semantic clinical drug
RxCUI 1113705
Semantic clinical drug · SCD
● Current RxNorm concept 93 FDA products
119 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI1113705
Official nameAcetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asacetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG per 15 ML Oral Solution; acetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG in 15 mL Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG per 30 ML Oral Solution; APAP 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution
FDA products mapped93
Package NDCs mapped119
Reported Medicaid activity (SDUD)11 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It depends on the product. The injection raises low blood pressure during anesthesia and, for some products, septic shock. Eye drops dilate the pupil, nasal products relieve conges...
- Be careful. Over-the-counter phenylephrine should not be used with a prescription MAOI or within 2 weeks of stopping one. If you aren't sure whether your medicine is an MAOI, ask m...
- With the injection, the most common are nausea, vomiting and headache. Call for help right away if you have chest pain, a very slow heartbeat, or pain or skin changes around the IV...
- Stop and talk to a doctor if you get nervousness, dizziness or sleeplessness. Also stop if symptoms last more than 7 days or come with a fever. Don't use more than the label recomm...
🕸️ Concept Web — How Acetaminophen 21.7 MG/ML / dextromethorphan hydr... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution
RxCUI 1113705 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 6
The active substance itself — no strength, form, or brand attached yet.
-
Acetaminophen
161IN -
Dextromethorphan
3289IN -
Phenylephrine
8163IN -
Acetaminophen / dextromethorphan / phenylephrine
705259MIN -
Dextromethorphan hydrobromide
102490PIN -
Phenylephrine hydrochloride
8164PIN
-
Acetaminophen
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Acetaminophen / dextromethorphan / phenylephrine Oral Solution
636782SCDF -
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Solution
2646461SCDFP -
Acetaminophen / dextromethorphan / phenylephrine Oral Liquid Product
1155917SCDG -
Acetaminophen / dextromethorphan / phenylephrine Oral Product
1155918SCDG -
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Liquid Product
2662803SCDGP -
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product
2660748SCDGP -
Oral Solution
316968DF -
Oral Liquid Product
1151137DFG - +1 more in this family
-
Acetaminophen / dextromethorphan / phenylephrine Oral Solution
-
Clinical & branded drugs 3
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Acetaminophen 21.7 MG/ML
332581SCDC -
Dextromethorphan hydrobromide 0.667 MG/ML
1014004SCDC -
Phenylephrine hydrochloride 0.333 MG/ML
1039296SCDC
-
Acetaminophen 21.7 MG/ML
-
Packs 2
Fixed collections of drugs packaged and sold together, like dose packs.
-
{1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) / 1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.417 MG/ML Oral Solution) } Pack
2637726GPCK -
{1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) / 1 (acetaminophen 21.7 MG/ML / diphenhydramine hydrochloride 0.833 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) } Pack
1803669GPCK
-
{1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) / 1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.417 MG/ML Oral Solution) } Pack
Showing up to 8 concepts per family — 19 of 20 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
{1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) / 1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.417 MG/ML Oral Solution) } Pack
GPCK · 2637726 -
{1 (acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 0.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) / 1 (acetaminophen 21.7 MG/ML / diphenhydramine hydrochloride 0.833 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) } Pack
GPCK · 1803669 -
Acetaminophen 21.7 MG/ML
SCDC · 332581 -
Dextromethorphan hydrobromide 0.667 MG/ML
SCDC · 1014004 -
Phenylephrine hydrochloride 0.333 MG/ML
SCDC · 1039296 -
Acetaminophen / dextromethorphan / phenylephrine Oral Solution
SCDF · 636782 -
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Solution
SCDFP · 2646461 -
Acetaminophen / dextromethorphan / phenylephrine Oral Liquid Product
SCDG · 1155917 -
Acetaminophen / dextromethorphan / phenylephrine Oral Product
SCDG · 1155918 -
Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Liquid Product
SCDGP · 2662803
📦 FDA Products & Package NDCs
93 products · 119 package NDCs
119 package NDCs map to RxCUI 1113705 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00067-8125-16 | 1 KIT in 1 CARTON (0067-8125-16) * 245.5 mL in 1 BOTTLE (0... | Theraflu ExpressMax Daytime Nighttime Value Pack | Haleon US Holdings LLC | 2015-07-15 |
| 00067-8127-08 | 245.5 mL in 1 BOTTLE (0067-8127-08) | Theraflu ExpressMax Daytime Severe Cold and Cough | Haleon US Holdings LLC | 2015-07-15 |
| 00113-0656-34 | 237 mL in 1 BOTTLE (0113-0656-34) | Good Sense Daytime non drowsy cold and flu | L. Perrigo Company | 2012-07-27 |
| 00113-0656-40 | 354 mL in 1 BOTTLE (0113-0656-40) | Good Sense Daytime non drowsy cold and flu | L. Perrigo Company | 2013-01-02 |
| 00113-6219-02 | 1 KIT in 1 CARTON (0113-6219-02) * 354 mL in 1 BOTTLE (011... | GOOD SENSE COMBO PACK DAYTIME AND NIGHTTIME | L. Perrigo Company | 2026-01-08 |
| 00363-0567-02 | 1 KIT in 1 CARTON (0363-0567-02) * 355 mL in 1 BOTTLE (036... | daytime nighttime cold and flu | Walgreen Company | 2012-09-06 |
| 00363-0666-34 | 237 mL in 1 BOTTLE (0363-0666-34) | Cold and Flu | Walgreen Company | 2014-02-07 |
| 00363-0666-40 | 355 mL in 1 BOTTLE (0363-0666-40) | Cold and Flu | Walgreen Company | 2014-02-07 |
| 00363-1213-02 | 1 KIT in 1 PACKAGE (0363-1213-02) * 355 mL in 1 BOTTLE, PL... | Cold and Flu Day, Night | Walgreen Company | 2022-11-14 |
| 00363-1213-99 | 1 KIT in 1 CARTON (0363-1213-99) * 355 mL in 1 BOTTLE, PLA... | Cold and Flu Day, Night | Walgreen Company | 2022-11-14 |
| 00363-1733-02 | 1 KIT in 1 CARTON (0363-1733-02) * 355 mL in 1 BOTTLE (036... | daytime nighttime cold and flu | Walgreen Company | 2017-07-13 |
| 00363-4661-12 | 355 mL in 1 BOTTLE, PLASTIC (0363-4661-12) | Cold and Flu Relief | Walgreens | 2020-07-30 |
| 00363-4670-24 | 1 KIT in 1 KIT (0363-4670-24) * 355 mL in 1 BOTTLE * 355... | Daytime Nighttime Cold and Cough | Walgreens | 2020-07-30 |
| 00363-9912-02 | 355 mL in 1 BOTTLE, PLASTIC (0363-9912-02) | Cold and Flu Day | Walgreen Company | 2022-11-14 |
| 00363-9974-08 | 237 mL in 1 BOTTLE, PLASTIC (0363-9974-08) | Cold and Flu Relief | Walgreens | 2022-09-30 |
| 11673-0765-01 | 354 mL in 1 BOTTLE (11673-765-01) | Daytime Cold and Flu | TARGET CORPORATION | 2024-06-30 |
| 11673-0823-02 | 1 KIT in 1 BOTTLE (11673-823-02) * 354 mL in 1 BOTTLE, PLA... | Daytime and Nighttime Cherry Cold and Flu | TARGET CORPORATION | 2024-05-01 |
| 11673-0921-02 | 1 KIT in 1 BOTTLE (11673-921-02) * 354 mL in 1 BOTTLE, PLA... | Daytime and Nighttime Cherry Cold and Flu | TARGET CORPORATION | 2024-05-01 |
| 21130-0467-24 | 1 KIT in 1 KIT (21130-467-24) * 355 mL in 1 BOTTLE * 355... | Daytime Nighttime Cold and Flu | Safeway, Inc. | 2018-09-30 |
| 21130-0580-08 | 237 mL in 1 BOTTLE, PLASTIC (21130-580-08) | Day Time Cold and Flu | Safeway, Inc. | 2025-12-01 |
| 21130-0580-12 | 355 mL in 1 BOTTLE, PLASTIC (21130-580-12) | Day Time Cold and Flu | Safeway, Inc. | 2025-12-01 |
| 21130-0866-08 | 237 mL in 1 BOTTLE, PLASTIC (21130-866-08) | Day Time Cold and Flu Relief non drowsy | Safeway, Inc. | 2015-08-31 |
| 21130-0866-12 | 355 mL in 1 BOTTLE, PLASTIC (21130-866-12) | Day Time Cold and Flu Relief non drowsy | Safeway, Inc. | 2015-08-31 |
| 21130-0947-06 | 236 mL in 1 BOTTLE (21130-947-06) | Daytime Cold and Flu | BETTER LIVING BRANDS, LLC | 2026-04-11 |
| 21130-0967-02 | 1 KIT in 1 BOTTLE (21130-967-02) * 354 mL in 1 BOTTLE, PLA... | Daytime and Nighttime Cherry Cold and Flu | BETTER LIVING BRANDS, LLC | 2025-03-01 |
| 24385-0005-34 | 237 mL in 1 BOTTLE (24385-005-34) | Good Neighbor Pharmacy Day Time | Amerisource Bergen | 2012-07-21 |
| 36800-0301-02 | 1 KIT in 1 CARTON (36800-301-02) * 355 mL in 1 BOTTLE (368... | TopCare Day Time Nite Time Cold and Flu Relief | Topco Associates LLC | 2018-09-08 |
| 36800-0522-34 | 237 mL in 1 BOTTLE (36800-522-34) | topcare day time cold and flu relief multi symptom relief | Topco Associates LLC | 2012-07-18 |
| 36800-0522-40 | 355 mL in 1 BOTTLE (36800-522-40) | topcare day time cold and flu relief multi symptom relief | Topco Associates LLC | 2012-07-10 |
| 37000-0033-24 | 1 KIT in 1 PACKAGE (37000-033-24) * 354 mL in 1 BOTTLE, PL... | Vicks DayQuil and Vicks NyQuil Cold and Flu | The Procter & Gamble Manufacturing Company | 2013-08-01 |
| 37808-0656-40 | 355 mL in 1 BOTTLE (37808-656-40) | DayTime | H E B | 2012-07-20 |
| 37808-0718-83 | 245 mL in 1 BOTTLE, PLASTIC (37808-718-83) | Daytime Severe Cold and Cough | H E B | 2023-03-31 |
| 37835-0526-02 | 355 mL in 1 BOTTLE, PLASTIC (37835-526-02) | Cold and Flu Daytime | Bi-Mart | 2023-01-06 |
| 37835-0527-12 | 355 mL in 1 BOTTLE (37835-527-12) | DAYTIME COLD AND FLU | BI-MART | 2025-05-01 |
| 41163-0567-02 | 1 KIT in 1 CARTON (41163-567-02) * 355 mL in 1 BOTTLE (411... | equaline daytime and nighttime cold and flu relief | United Natural Foods, Inc. dba UNFI | 2012-08-14 |
| 41163-0656-40 | 355 mL in 1 BOTTLE (41163-656-40) | equaline daytime cold and flu relief | United Natural Foods, Inc. dba UNFI | 2012-07-11 |
| 41226-0772-01 | 354 mL in 1 BOTTLE (41226-772-01) | Daytime Cold and Flu | Kroger | 2024-04-30 |
| 41226-0790-02 | 1 KIT in 1 PACKAGE (41226-790-02) * 354 mL in 1 BOTTLE (41... | Daytime Nighttime Cold and Flu | Kroger | 2024-04-30 |
| 41250-0656-40 | 355 mL in 1 BOTTLE (41250-656-40) | Daytime cold and flu non drowsy | Meijer Distribution Inc | 2008-08-30 |
| 41250-0733-02 | 1 KIT in 1 CARTON (41250-733-02) * 355 mL in 1 BOTTLE (412... | daytime nitetime cold and flu | Meijer, Inc. | 2012-10-24 |
| 41520-0032-40 | 355 mL in 1 BOTTLE (41520-032-40) | CareOne DayTime Cold and Flu | American Sales Company | 2017-09-18 |
| 42507-0522-40 | 355 mL in 1 BOTTLE (42507-522-40) | Cold and Flu | HyVee Inc | 2014-01-10 |
| 49035-0466-12 | 355 mL in 1 BOTTLE, PLASTIC (49035-466-12) | Daytime Cold and Flu Non drowsy | EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC) | 2015-06-30 |
| 49035-0718-02 | 1 KIT in 1 CARTON (49035-718-02) * 355 mL in 1 BOTTLE (490... | equate daytime cold and flu nighttime cold and flu | Wal-Mart Stores Inc | 2020-04-21 |
| 49035-0726-40 | 355 mL in 1 BOTTLE (49035-726-40) | equate daytime cold and flu | Wal-Mart Stores Inc | 2019-09-24 |
| 49580-0466-01 | 296 mL in 1 BOTTLE, PLASTIC (49580-0466-1) | Daytime Cold and Flu | P & L Development, LLC | 2015-06-30 |
| 49580-0466-02 | 355 mL in 1 BOTTLE, PLASTIC (49580-0466-2) | Daytime Cold and Flu | P & L Development, LLC | 2015-06-30 |
| 49580-0466-04 | 118 mL in 1 BOTTLE, PLASTIC (49580-0466-4) | Daytime Cold and Flu | P & L Development, LLC | 2015-06-30 |
| 49580-0466-06 | 177 mL in 1 BOTTLE, PLASTIC (49580-0466-6) | Daytime Cold and Flu | P & L Development, LLC | 2015-06-30 |
| 49580-0501-08 | 245 mL in 1 BOTTLE, PLASTIC (49580-0501-8) | Severe Cold and Cough Relief Daytime | P & L Development, LLC | 2021-03-26 |
Observed labelers:
The Procter & Gamble Manufacturing Company (11) ·
Walgreen Company (7) ·
P & L Development, LLC (5) ·
Safeway, Inc. (5) ·
AptaPharma Inc. (4) ·
Best Choice (Valu Merchandisers Company) (4)
· +43 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.