Advil Vs. Motrin IB: What Is The Difference?
In our latest question and answer, the pharmacist discusses the difference between Motrin IB and Advil.

Question
Hi, I'm wondering if there is any difference between Advil and Motrin? I was told one was better than the other. Thanks!

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 16, 2025
Key points
- Motrin and Advil are brand names and contain the same active ingredient, ibuprofen, an NSAID (non-steroidal antiinflammatory drug).
- Both Motrin and Advil have products for adults, children, and infants.
- As a brand name, 'Advil' is used on more commercially available products than Motrin is.
- Advil has a 'cold and allergy' product line, while Motrin does not.
Hello and thanks for reaching out!
The simple answer to this is that there is no significant difference between Advil and Motrin IB. Both are branded products that contain the same active ingredient, ibuprofen.
Motrin IB is a brand name owned by Johnson & Johnson while Motrin is owned by GlaxoSmithKline.
Now, each brand has several different product formulations available (e.g. liquid gels, chewable tablets etc...) and I detail these in the next sections.
The 'Advil' brand has far more individual products on the market than Motrin does, and I would say that is the major difference between the two brands. When it comes to the actual drug (or drugs) they contain, that is where there is no difference in comparable products.
Motrin IB Products
Motrin (sometimes referred to as Motrin IB) contains the active ingredient ibuprofen ('IB' stands for ibuprofen in Motrin IB), which is classified as an NSAID (non-steroidal anti-inflammatory drug).
Below is a chart showing all of the commercially available Motrin IB products.
Product | Active Ingredient(s) | Dosage Form |
---|---|---|
MOTRIN IB Migraine Liquid Gels | ibuprofen 200mg (per Liquid Gel) | Gel |
Children's MOTRIN Chewable Tablets | ibuprofen 100mg (per Chewable Tablet) | Chewable |
MOTRIN IB Liquid Gels | ibuprofen 200mg (per Liquid Gel) | Gel |
MOTRIN IB Caplets | ibuprofen 200mg (per Caplet) | Caplet |
MOTRIN PM Caplets | ibuprofen 200mg; diphenhydramine 38mg (per Caplet) | Caplet |
Children's MOTRIN Oral Suspension |
ibuprofen 100mg/5mL | Suspension |
Infants' MOTRIN Drops | ibuprofen 50mg/1.25mL | Suspension |
Advil Products
As mentioned, Advil, just like Motrin, contains the active ingredient ibuprofen.
Below is a chart containing all of the commercially available Advil products (aside from their 'cold & allergy' products).
Product | Active Ingredient(s) | Dosage Form |
---|---|---|
Advil Coated Tablets | ibuprofen 200mg (per Tablet) | Tablet |
Advil Coated Gel Caplets | ibuprofen 200mg (per Caplet) | Caplet |
Advil Liqui-Gels | ibuprofen 200mg (per Liquid Gel) | Gel |
Advil Liqui-Gels Minis | ibuprofen 200mg (per Liquid Gel) | Gel |
Advil Migraine | ibuprofen 200mg (per Liquid Gel) | Gel |
Advil Dual Action |
ibuprofen 125mg; acetaminophen 250mg (per Caplet) | Caplet |
Junior Strength Advil Chewables | ibuprofen 100mg (per Chewable Tablet) | Chewable |
Infants' Advil Drops | ibuprofen 50mg/1.25mL | Suspension |
Children's Advil Suspension | ibuprofen 100mg/5mL | Suspension |
Advil PM (Caplet) | ibuprofen 200mg; diphenhydramine 38mg (per Caplet) | Caplet |
Advil PM (Liqui-Gel) | ibuprofen 200mg; diphenhydramine 25 mg (per Liquid Gel) | Gel |
I do want to mention here that Advil also has several additional products not listed above.
The Advil brand name is used for several multi-symptom cold and allergy products, such as 'Advil Multi-Symptom Cold & Flu', and 'Advil Sinus Congestion & Pain'.
Final Words
I hope this answer helped clear up any confusion!
It can be a little confusing sorting out all the different products, but the main takeaway here is that most Motrin and Advil products contain the exact same active ingredient (ibuprofen).
You really can't go wrong grabbing either product and you can expect the same relief from both.
As an alternative, most stores carry their own store/generic brand of ibuprofen, which are generally cheaper than Mortin or Advil. For example, Walgreens, CVS, and Rite Aid all have their own.
Thanks again!
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Dr. Brian Staiger, PharmD
- 7153 views