Benadryl (Diphenhydramine) With Ibuprofen Interaction Details

Answer

There is no known drug interaction between Benadryl (diphenhydramine) and ibuprofen. They are considered safe to take together.

In fact, there are a number of products on the market that contain both drugs in combination with one another in a single pill. These products are generally used for the occasional relief of insomnia associated with minor aches and pains.

For example, one such product is Advil PM, which contains:

• Ibuprofen
• Diphenhydramine citrate

Several different generic products also contain both ibuprofen and diphenhydramine (like this one available at Walgreens).

So, to answer your question specifically, you don't need to wait any amount of time after taking ibuprofen to take Benadryl. They can be taken at the same time safely. You can likely save some money by buying a product that contains both drugs versus buying each drug separately.

Final Words

Thanks so much for reaching out! Contact us again anytime.