Didanosine
68 interactions 224 cited referencesDidanosine is used along with other medications to treat human immunodeficiency virus (HIV) infection. Didanosine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although didanosine does not cure HIV, it may decrease your ch… Read the full Didanosine drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Didanosine Amprenavir Reduced amprenavir efficacy Details Didanosine Atevirdine Reduced clinical efficacy of atevirdine Details Didanosine Cinoxacin Decreased cinoxacin effectiveness Details Didanosine Delavirdine Rescriptor® Decreased serum levels of both delavirdine and didanosine Details Didanosine Enoxacin Decreased enoxacin effectiveness Details Didanosine Ganciclovir Cytovene® Oral An increased risk of didanosine toxicity (neuropathy, diarrhea, pancreatitis) Details Didanosine Gatifloxacin Zymaxid Decreased gatifloxacin effectiveness Details Didanosine Gemifloxacin Factive Decreased gemifloxacin bioavailability Details Didanosine Grepafloxacin Decreased grepafloxacin effectiveness Details Didanosine Indinavir Decreased bioavailability and therapeutic efficacy of indinavir Details Didanosine Itraconazole Sporanox Decreased itraconazole effectiveness Details Didanosine Ketoconazole Extina Decreased ketoconazole effectiveness Details Didanosine Levofloxacin Levaquin Decreased levofloxacin effectiveness Details Didanosine Lomefloxacin Decreased lomefloxacin effectiveness Details Didanosine Metoclopramide Increased didanosine plasma concentrations Details Didanosine Moxifloxacin Avelox Decreased moxifloxacin effectiveness Details Didanosine Nalidixic Acid Decreased nalidixic acid serum concentrations by buffered didanosine preparations Details Didanosine Nirmatrelvir Inactivation of both drugs Details Didanosine Norfloxacin Decreased norfloxacin serum and urine levels Details Didanosine Ofloxacin Floxin® Decreased ofloxacin bioavailability and potential loss of ofloxacin efficacy Details Didanosine Ranitidine Increased didanosine plasma concentrations and decreased ranitidine plasma concentrations Details Didanosine Rifabutin Mycobutin Increased didanosine plasma concentrations Details Didanosine Ritonavir Norvir Inactivation of both drugs Details Didanosine Sulfamethoxazole Sustain Reduced sulfamethoxazole exposure Details Didanosine Tipranavir Aptivus Decreased didanosine plasma concentrations Details Didanosine Trimethoprim Primsol Increased didanosine plasma concentrations and potential for increased trimethoprim plasma concentrations Details Didanosine Trovafloxacin Mesylate Decreased trovafloxacin effectiveness Details Didanosine Valganciclovir Valcyte An increased risk of didanosine toxicity (neuropathy, diarrhea, pancreatitis) Details Didanosine Ganciclovir Injection Cytovene® I.V.® An increased risk of didanosine toxicity (neuropathy, diarrhea, pancreatitis) Details Didanosine Ganciclovir Ophthalmic Zirgan An increased risk of didanosine toxicity (neuropathy, diarrhea, pancreatitis) Details Didanosine Gatifloxacin Ophthalmic Zymar® Decreased gatifloxacin effectiveness Details Didanosine Ketoconazole Topical Extina® Foam Decreased ketoconazole effectiveness Details Didanosine Levofloxacin Injection Levaquin Decreased levofloxacin effectiveness Details Didanosine Metoclopramide Injection Gimoti Increased didanosine plasma concentrations Details Didanosine Metoclopramide Nasal Spray Gimoti Increased didanosine plasma concentrations Details Didanosine Moxifloxacin Injection Avelox Decreased moxifloxacin effectiveness Details Didanosine Moxifloxacin Ophthalmic Moxeza® Decreased moxifloxacin effectiveness Details Didanosine Ofloxacin Ophthalmic Ocuflox Decreased ofloxacin bioavailability and potential loss of ofloxacin efficacy Details Didanosine Ofloxacin Otic Floxin® Otic Decreased ofloxacin bioavailability and potential loss of ofloxacin efficacy DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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