Drug & supplement interaction

1-epiandrosterone + Cedazuridine, Decitabine

Cedazuridine, Decitabine brand name: Inqovi.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 1-epiandrosterone and Cedazuridine, Decitabine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

1-epiandrosterone and Cedazuridine, Decitabine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cedazuridine, Decitabine and 1-epiandrosterone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 1-epiandrosterone at all — not against Cedazuridine, Decitabine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

1-epiandrosterone safety at a glance

1-epiandrosterone overall Avoid It acts like an anabolic steroid and has limited safety data, so caution and medical guidance are strongly advised.
Pregnancy Possibly Unsafe When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cedazuridine, Decitabine and 1-epiandrosterone? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Cedazuridine, Decitabine’s Own FDA Label Lists

This is not an interaction — none of it involves 1-epiandrosterone. These are the most notable effects listed in the ADVERSE REACTIONS section of Cedazuridine, Decitabine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on
  • Trouble swallowing Worth acting on
  • Unsteadiness Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on
  • Wheezing Worth acting on
  • An irregular heartbeat Worth acting on
  • A severe skin reaction Worth acting on
  • Chest pain Worth acting on
  • A low platelet count Worth acting on

Showing the 10 most notable of 45 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Cedazuridine, Decitabine. Read the label on DailyMed › 1-epiandrosterone’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no 1-epiandrosterone side to compare — that is a limit of the record, not a statement that 1-epiandrosterone has no side effects.

Special populations

1-epiandrosterone in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss, and acne. Prohormones have also been associated with hepatotoxicity and increased risk of cardiovascular disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing prohormones are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Cedazuridine, Decitabine

This page covers 1-epiandrosterone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cedazuridine, Decitabine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Cedazuridine, Decitabine page

“Inqovi pairs decitabine, an oral chemotherapy for certain blood cancers, with cedazuridine, whose whole job is helping the decitabine absorb properly. That is exactly why this list warrants genuine care, because every flagged supplement works the same way, by interfering with absorption in the gut.”

Reviewed by 2 · Jul 18, 2026

Open the Cedazuridine, Decitabine interaction page

How much people look this up

Where 1-epiandrosterone and Cedazuridine, Decitabine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 1-epiandrosterone
Steady interest

#849 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cedazuridine, Decitabine
Top 10%

#212 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 1-epiandrosterone reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The 1-epiandrosterone and Cedazuridine, Decitabine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 1-epiandrosterone

What is 1-epiandrosterone?

1-epiandrosterone
  • Muscle building
  • Athletic performance
  • Improving body composition
  • Strength gains

1-epiandrosterone (often sold as a '1-andro' prohormone) is a steroid-related compound marketed to bodybuilders for muscle and strength gains, but solid human evidence is very limited and the safety profile is poorly understood. Because it can act like an anabolic steroid in the body and may carry liver, hormonal, and cardiovascular risks, most people should avoid it and talk to a pharmacist or doctor first.

Not a plant; a synthetic or lab-made steroid compound (prohormone) · Capsules, tablets, sometimes part of multi-ingredient bodybuilding 'prohormone' supplements

An interaction check asks whether these two react with each other — it does not ask whether 1-epiandrosterone is a good idea for someone in your situation. Here is what our 1-epiandrosterone record says about it on its own.

1-epiandrosterone: dosing

There is no established safe or effective dose for 1-epiandrosterone. Because these products can act like steroids and may carry real risks, do not assume "more is better." The safest choice for most people is to avoid it.

From our 1-epiandrosterone monograph — the full record covers uses, side effects and every documented interaction.

Read the full 1-epiandrosterone monograph & all interactions
Medication

About Decitabine and Cedazuridine

What Is Decitabine and Cedazuridine Used For?

Brand name: Inqovi

Inqovi is used to treat adult patients with myelodysplastic syndromes (MDS) — a group of blood cancers where bone marrow doesn't make enough healthy blood cells — and chronic myelomonocytic leukemia (CMML). It covers several subtypes of MDS, including refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, and both previously treated and newly diagnosed disease.

Inqovi is also approved in combination with venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are 75 years of age or older, or in adults of any age whose other health conditions make intensive chemotherapy unsafe.

See full Decitabine and Cedazuridine drug information
Keep checking

Other Drugs & 1-epiandrosterone

Browse every other medication we’ve checked against 1-epiandrosterone — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

1-epiandrosterone References

The 1 references that drive our 1-epiandrosterone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 1-epiandrosterone and Cedazuridine, Decitabine Together: Common Questions

Is it safe to take 1-epiandrosterone with Cedazuridine, Decitabine?
We do not list a known interaction between 1-epiandrosterone and Cedazuridine, Decitabine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Cedazuridine, Decitabine interact with any supplements?
Yes. Cedazuridine, Decitabine has documented interactions with 17 supplements in our database — 1-epiandrosterone is not one of them. The Cedazuridine, Decitabine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cedazuridine, Decitabine and 1-epiandrosterone?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.