Drug & supplement interaction

7-keto-dhea + Oxazepam

Oxazepam brand name: Serax.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 7-keto-dhea and Oxazepam in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

7-keto-dhea and Oxazepam

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Oxazepam and 7-keto-dhea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 7-keto-dhea at all — not against Oxazepam, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

7-keto-dhea safety at a glance

7-keto-dhea overall Use caution Short-term use appears generally tolerated in small studies, but long-term safety is not well established.
Pregnancy Avoid Not enough safety data, and hormone-related supplements are best avoided during pregnancy.
Breastfeeding Avoid No reliable safety information is available, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Oxazepam and 7-keto-dhea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests 7-keto-dhea and Oxazepam May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Dizziness Additional detail

    7-keto-dhea

    “Orally, 7-keto-DHEA has been associated with one report of vertigo in one clinical study.”

    7-keto-dhea · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 92185. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

    Oxazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Oxazepam. Read the label on DailyMed ›

  • Nausea Additional detail

    7-keto-dhea

    “Orally, 7-keto-DHEA has been associated with two reports of nausea in one clinical study.”

    7-keto-dhea · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 92185. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

    Oxazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Oxazepam. Read the label on DailyMed ›

Effects for Oxazepam come from the ADVERSE REACTIONS section of its FDA label; effects for 7-keto-dhea come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Oxazepam Is Prescribed For, and What 7-keto-dhea Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Oxazepam is a prescription medicine with approved uses on its FDA label. 7-keto-dhea is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Oxazepam is prescribed for: Oxazepam capsules are used to manage anxiety disorders and for short-term relief of anxiety symptoms. They are also helpful for anxiety that occurs alongside depression. Oxazepam is particularly useful for older adults experiencing anxiety, tension, agitation, or irritability. It is also used for people going through alcohol withdrawal who have tremors, agitation, or anxiety.

7-keto-dhea has been studied for:

  • Anxiety studied, not established 7-keto-dhea has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    7-keto-dhea for anxiety

    Although there has been interest in using oral 7-keto-DHEA for anxiety, there is insufficient reliable information about the clinical effects of 7-keto-DHEA for this purpose.

  • Depression studied, not established 7-keto-dhea has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    7-keto-dhea for depression

    Although there has been interest in using oral 7-keto-DHEA for depression, there is insufficient reliable information about the clinical effects of 7-keto-DHEA for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Oxazepam on your own; if you are taking 7-keto-dhea for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Oxazepam

This page covers 7-keto-dhea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Oxazepam page lists 119 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 8 major · 94 moderate · 17 minor.

From our pharmacist’s overview on the Oxazepam page

“The single biggest hazard with oxazepam (Serax), a benzodiazepine prescribed for anxiety and alcohol withdrawal, is stacked sedation, and this is a list to treat with genuine respect. Nearly two thirds of the supplements and foods on this page add their own drowsiness on top of the drug's, and the worst of them can depress breathing it…”

Reviewed by 2 · Jul 18, 2026

Open the Oxazepam interaction page

One more smart check

Taking 7-keto-dhea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 207 real supplement products containing 7-keto-dhea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 7-keto-dhea. Even though 7-keto-dhea itself has no known interaction with Oxazepam, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 7-keto-dhea and Oxazepam Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 7-keto-dhea
Steady interest

#895 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Oxazepam
Top half

#1,282 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 7-keto-dhea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The 7-keto-dhea and Oxazepam records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 7-keto-dhea

What is 7-keto-dhea?

7-keto-dhea
  • Weight loss and fat burning
  • Boosting metabolism
  • Supporting muscle mass
  • Improving body composition
  • Anti-aging support

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thought to convert into estrogen or testosterone, but the evidence that it helps with weight or metabolism is limited and comes from small studies. Talk with your pharmacist or doctor before trying it, especially if you have any health conditions.

Not applicable (a manufactured metabolite of DHEA) · Capsules, tablets, powders (often in weight-loss or 'metabolism' blends)

An interaction check asks whether these two react with each other — it does not ask whether 7-keto-dhea is a good idea for someone in your situation. Here is what our 7-keto-dhea record says about it on its own.

7-keto-dhea: dosing

There is no official or well-established standardized dose for 7-keto-DHEA. Doses used in studies and on product labels have varied, and we cannot recommend a specific amount.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our 7-keto-dhea monograph — the full record covers uses, side effects and every documented interaction.

Read the full 7-keto-dhea monograph & all interactions
Medication

About Oxazepam

What Is Oxazepam Used For?

Brand name: Serax

Oxazepam capsules are used to manage anxiety disorders and for short-term relief of anxiety symptoms. They are also helpful for anxiety that occurs alongside depression.

Oxazepam is particularly useful for older adults experiencing anxiety, tension, agitation, or irritability. It is also used for people going through alcohol withdrawal who have tremors, agitation, or anxiety.

Most-Reported Side Effects for Oxazepam

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Toxicity to various agents 2,858 reports
Drug abuse 1,522 reports
Fall 1,520 reports
Hypotension 1,402 reports
Coma 1,108 reports
See full Oxazepam drug information
Keep checking

Other Drugs & 7-keto-dhea

Browse every other medication we’ve checked against 7-keto-dhea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

7-keto-dhea References

The 2 references that drive our 7-keto-dhea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 7-keto-dhea and Oxazepam Together: Common Questions

Is it safe to take 7-keto-dhea with Oxazepam?
We do not list a known interaction between 7-keto-dhea and Oxazepam. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do 7-keto-dhea and Oxazepam have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are 7-keto-dhea and Oxazepam used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for 7-keto-dhea in each. That is a conversation for your prescriber, especially if Oxazepam is being adjusted to a target.
Does Oxazepam interact with any supplements?
Yes. Oxazepam has documented interactions with 119 supplements in our database — 7-keto-dhea is not one of them. The Oxazepam interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Oxazepam and 7-keto-dhea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.