Abuta + Naltrexone Hydrochloride, Oxycodone Hydrochloride
Naltrexone Hydrochloride, Oxycodone Hydrochloride brand name: Troxyca ER.
We found no known interaction between Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Naltrexone Hydrochloride, Oxycodone Hydrochloride and Abuta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Abuta safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Naltrexone Hydrochloride, Oxycodone Hydrochloride
Interactions in our licensed database are recorded against drug classes, not just single drug names. Naltrexone Hydrochloride, Oxycodone Hydrochloride is filed under 7 classifications — including narcotic drugs, cytochrome p450 2d6 (cyp2d6) substrates, cns depressants. Abuta has documented interactions with 1 drug class — the most serious being diuretic drugs (moderate) — and none of Naltrexone Hydrochloride, Oxycodone Hydrochloride’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Abuta Does Interact With Other Medications
Abuta has 75 moderate known drug interactions in our database — Naltrexone Hydrochloride, Oxycodone Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Abuta
We haven’t checked that one against Abuta yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Abuta. Pick one to open its full report.
See Every Supplement That Interacts With Naltrexone Hydrochloride, Oxycodone Hydrochloride
This page covers Abuta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naltrexone Hydrochloride, Oxycodone Hydrochloride page lists 145 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).
By severity: 8 major · 114 moderate · 23 minor.
From our pharmacist’s overview on the Naltrexone Hydrochloride, Oxycodone Hydrochloride page
“Alcohol tops this list. Beer and wine both carry major, well-documented interactions with Troxyca ER (naltrexone and oxycodone hydrochloride), an extended-release opioid, because adding a second sedative to an opioid can slow breathing, not just deepen drowsiness.”
Reviewed by 2 · Jul 18, 2026
Open the Naltrexone Hydrochloride, Oxycodone Hydrochloride interaction page
Taking Abuta as Part of a Dietary Supplement Product? Check It for Interactions
We hold 1 real supplement products containing Abuta, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Abuta. Even though Abuta itself has no known interaction with Naltrexone Hydrochloride, Oxycodone Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#475 of 1,452 supplements looked up here in the last 7 days
#349 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Abuta reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Abuta
What is Abuta?
- Menstrual cramps and women's health
- Kidney and urinary tract complaints
- Digestive upset
- Fever
- Traditional support during pregnancy and childbirth
Abuta (Cissampelos pareira) is a tropical climbing plant used in traditional medicine, especially for menstrual and urinary complaints. Good-quality human studies are lacking, so its benefits and safety are not well established. Because of uncertain safety—and its traditional use to affect the uterus—it should be avoided during pregnancy and breastfeeding and discussed with a pharmacist or doctor first.
Cissampelos pareira · Menispermaceae · Root (most common), with bark, seeds, and above-ground parts also used · Dried root, tea/decoction, tincture, capsules, powder
An interaction check asks whether these two react with each other — it does not ask whether Abuta is a good idea for someone in your situation. Here is what our Abuta record says about it on its own.
Abuta: dosing
There is no established, standardized dose of abuta. Traditional preparations vary, and modern supplements come in different strengths and forms, so there is no single recommended amount that has been proven safe and effective.If you choose to use a product, follow the directions on the label and do not exceed them.
From our Abuta monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Abuta
Browse every other medication we’ve checked against Abuta — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
75 interactions
- Hydrochlorothiazide ›
- Trichlormethiazide ›
- Bendroflumethiazide ›
- Metolazone ›
- Spironolactone ›
- Acetazolamide ›
- Chlorthalidone ›
- Cyclothiazide ›
- Indapamide ›
- Mannitol ›
- Methyclothiazide ›
- Torsemide ›
- Ammonium Chloride ›
- Benzthiazide ›
- Bumetanide ›
- Chlorothiazide ›
- Ethacrynic Acid ›
- Furosemide ›
- Hydroflumethiazide ›
- Methazolamide ›
- Polythiazide ›
- Quinethazone ›
- Theobromine ›
- Urea ›
- Hydrochlorothiazide, Triamterene ›
- Amiloride, Hydrochlorothiazide ›
- Hydrochlorothiazide, Methyldopa ›
- Hydrochlorothiazide, Reserpine ›
- Hydrochlorothiazide, Spironolactone ›
- Acetaminophen, Pamabrom, Pyrilamine ›
- Atenolol, Chlortalidone ›
- Chlorothiazide, Methyldopa ›
- Hydralazine, Hydrochlorothiazide, Reserpine ›
- Reserpine, Trichlormethiazide ›
- Bendroflumethiazide, Potassium ›
- Captopril, Hydrochlorothiazide ›
- Chlorthalidone, Clonidine ›
- Deserpidine, Hydrochlorothiazide ›
- Deserpidine, Methyclothiazide ›
- Furosemide, Potassium ›
- Hydralazine, Hydrochlorothiazide ›
- Hydrochlorothiazide, Lisinopril ›
- Hydroflumethiazide, Reserpine ›
- Acetaminophen, Caffeine, Pyrilamine ›
- Atenolol, Chlorthalidone ›
- Azilsartan, Chlorthalidone ›
- Benazepril, Hydrochlorothiazide ›
- Bendroflumethiazide, Nadolol ›
- Bendroflumethiazide, Rauwolfia Serpentina ›
- Bisoprolol, Hydrochlorothiazide ›
- Bumetanide, Potassium ›
- Caffeine, Potassium Salicylate, Salicylamide ›
- Candesartan Cilexetil, Hydrochlorothiazide ›
- Chlorothiazide, Reserpine ›
- Cryptenamine, Methyclothiazide ›
- Enalapril Maleate, Hydrochlorothiazide ›
- Fosinopril, Hydrochlorothiazide ›
- Guanethidine, Hydrochlorothiazide ›
- Hydrochlorothiazide, Irbesartan ›
- Hydrochlorothiazide, Labetalol ›
Showing 60 of 75 moderate interactions — see all 75 on the Abuta page.
No interaction 2,754 drugs checked — show the list
We also checked Abuta against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Rivaroxaban ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Escitalopram ›
- Abemaciclib ›
- Clopidogrel ›
- Tadalafil ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Ibuprofen ›
- Tirzepatide ›
- Methamphetamine ›
- Hydroxyurea ›
- Semaglutide ›
- Warfarin Sodium ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Amitriptyline ›
- Methotrexate ›
- Bendamustine ›
- Acyclovir ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Pregabalin ›
- Lamotrigine ›
- Azithromycin ›
- Acetaminophen, Codeine ›
- Isotretinoin ›
- Gabapentin ›
- Dextroamphetamine ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Naproxen ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,754 medications checked with no known interaction — see the full Abuta list.
Abuta References
The 1 references that drive our Abuta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Sayana SB, Khanwelkar CC, Nimmagadda VR, et al. Evaluation of diuretic activity of alcoholic extract of roots of cissampelos pareira in albino rats. J Clin Diagn Res. 2014;8(5):HC01-4.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride Together: Common Questions
Is it safe to take Abuta with Naltrexone Hydrochloride, Oxycodone Hydrochloride?
How was the Abuta and Naltrexone Hydrochloride, Oxycodone Hydrochloride combination checked?
Does Abuta interact with any other medications?
Does Naltrexone Hydrochloride, Oxycodone Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.