Drug & supplement interaction

Aletris + Gemcitabine

Gemcitabine brand name: Gemzar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Aletris and Gemcitabine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Aletris and Gemcitabine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Gemcitabine and Aletris in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Aletris safety at a glance

Aletris overall Use caution Limited modern safety data; large or fresh doses may cause stomach upset.
Pregnancy Possibly Unsafe When used orally due to the possibility that aletris contains components that cause estrogenic activity and oxytocin (Pitocin) antagonism; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally due to the possibility that aletris contains components that cause estrogenic activity and oxytocin (Pitocin) antagonism; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Gemcitabine and Aletris? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Gemcitabine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Gemcitabine is filed under 2 classifications — antineoplastics, hepatotoxic drugs. Aletris has documented interactions with 4 drug classes — the most serious being estrogens (moderate), antacids (minor) and h2-blockers (minor) — and none of Gemcitabine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Aletris Does Interact With Other Medications

Aletris has 41 moderate, 36 minor known drug interactions in our database — Gemcitabine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 41 Minor 36 No known interaction 2,753 (incl. Gemcitabine)
Taking anything else?

Check Another of Your Medications Against Aletris

Covers the 2,830 medications we’ve checked against Aletris. Pick one to open its full report.

What to actually watch for

What Aletris Itself Has Been Linked To

This is not an interaction — nothing below involves Gemcitabine. It is the side-effect record for Aletris on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Aletris, this list is the first place to look.

  • Dizziness Additional detail

    “There is currently a limited amount of information available about the adverse effects of aletris. Orally, aletris has been reported to cause colic, stupefaction, and vertigo (6).”

    Aletris · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

    “Orally, small doses of aletris have been reported to cause stupefaction and vertigo (6).”

    Aletris · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Everything above comes from the Natural Medicines adverse-effect record for Aletris — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Gemcitabine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Gemcitabine column appears here.

Special populations

Aletris in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally due to the possibility that aletris contains components that cause estrogenic activity and oxytocin (Pitocin) antagonism; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Gemcitabine

This page covers Aletris only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Gemcitabine page lists 39 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).

By severity: 3 major · 35 moderate · 1 minor.

Open the Gemcitabine interaction page

One more smart check

Taking Aletris as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Aletris, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Aletris. Even though Aletris itself has no known interaction with Gemcitabine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Aletris and Gemcitabine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Aletris
Steady interest

#807 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Gemcitabine
Steady interest

#2,058 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Aletris reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Aletris and Gemcitabine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Aletris

What is Aletris?

Aletris
  • Menstrual complaints
  • Digestive upset and colic
  • Loss of appetite
  • Female reproductive tonic
  • Rheumatic discomfort

Aletris (true unicorn root or colic root) is a North American herb traditionally used for menstrual problems and digestive complaints, but there is little to no modern human research to show it works. Because safety is poorly studied, it should be avoided during pregnancy and breastfeeding, and anyone considering it should first talk with a pharmacist or doctor.

Aletris farinosa · Nartheciaceae · Root and rhizome · Dried root, tincture, liquid extract, capsules, tea

An interaction check asks whether these two react with each other — it does not ask whether Aletris is a good idea for someone in your situation. Here is what our Aletris record says about it on its own.

Aletris: dosing

There is no established, scientifically supported dose for Aletris. Traditional dosing has varied widely depending on the form (dried root, tea, or tincture) and is not based on modern research.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Aletris monograph — the full record covers uses, side effects and every documented interaction.

Read the full Aletris monograph & all interactions
Medication

About Gemcitabine Injection

What Is Gemcitabine Injection Used For?

Brand name: Gemzar

Gemcitabine Injection (available as Avgemsi, Gemcitabine, and Infugem) is used to treat several types of cancer. It is given in combination with carboplatin for advanced ovarian cancer that has returned at least 6 months after platinum-based treatment, and in combination with paclitaxel as a first-line treatment for metastatic breast cancer after prior chemotherapy with an anthracycline (a specific class of chemo drug).

It is also given in combination with cisplatin for non-small cell lung cancer (NSCLC) that cannot be removed surgically or has spread. For pancreatic cancer that is locally advanced or has spread, it is used as a single agent — including in patients who have already been treated with fluorouracil.

Most-Reported Side Effects for Gemcitabine

From FAERS, the FDA’s public side-effect reporting system (53,020 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 4,850 reports
Thrombocytopenia 3,706 reports
Neutropenia 3,295 reports
Anemia 3,084 reports
Malignant neoplasm progression 2,912 reports
See full Gemcitabine Injection drug information
Keep checking

Other Drugs & Aletris

Browse every other medication we’ve checked against Aletris — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
41Moderate
36Minor
2,752No known interaction
41 Moderate 36 Minor 2,752 No interaction
Moderate

41 interactions

Minor

36 interactions

No interaction 2,752 drugs checked — show the list

We also checked Aletris against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,752 medications checked with no known interaction — see the full Aletris list.

See the full Aletris interactions page
See every supplement checked against Gemcitabine, ranked by severity
Evidence & sources

Aletris References

The 4 references that drive our Aletris monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Aletris and Gemcitabine Together: Common Questions

Is it safe to take Aletris with Gemcitabine?
We do not list a known interaction between Aletris and Gemcitabine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Aletris and Gemcitabine combination checked?
Interactions in our licensed database are recorded against drug classes. Gemcitabine is filed under 2 classifications, and Aletris has documented interactions with 4 drug classes — none of Gemcitabine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Aletris interact with any other medications?
Yes. Aletris has 77 documented drug interactions in our database — Gemcitabine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Gemcitabine interact with any supplements?
Yes. Gemcitabine has documented interactions with 39 supplements in our database — Aletris is not one of them. The Gemcitabine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Aletris monograph Uses, safety profile, and every drug interaction in one place Gemcitabine Injection drug information The full plain-English guide to this medication Gemcitabine supplement interactions Every supplement checked against Gemcitabine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Gemcitabine and Aletris?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.