Aletris - Ortho Evra (Norelgestromin, Ethinyl Estradiol) Interaction
Herbal: Aletris
Also Known As: Aletris farinosa, Ague, Ague Grass, Ague Root, Aloerot, Blazing Star, Colic Root, Crow Corn, Devil's-bit, Licorne Vraie, Stargrass, Starwort, True Unicorn Root, Unicorn Root, Whitetube Stargrass
Drug: Norelgestromin, Ethinyl Estradiol
Brand names:
Ortho Evra, Evra
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Norelgestromin, Ethinyl Estradiol is classified as belonging to the following category: Estrogens
Aletris might have estrogenic effects. Theoretically, use of aletris with estrogens might increase the risk for additive adverse effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Aletris Overview
Aletris farinosa, commonly known as True Unicorn Root or Colic Root, is a perennial herb native to North America. The plant is characterized by its slender, erect stem and narrow leaves, with small, white flowers clustered at the top. The part of aletris used for its medicinal properties is the root, which contains a variety of compounds including a cheilanthane sesterterpene. This herb has been traditionally employed for addressing menstrual complaints, with some of its constituents believed to possess estrogenic activity.
Aletris - More Interactions
Aletris interacts with 77 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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