Amaranth - Promacta (Eltrombopag) Interaction
Herbal: Amaranth
Also Known As: Amaranthus blitum, Amaranthus caudatus, Amaranthus cruentus, Amaranto, Chua, Huantli, Huatlí, Kantanoty, Lady Bleeding, Love-Lies-Bleeding, Lovely Bleeding, Pilewort, Prickly Amaranth, Prince's Feather, Rajgira, Ramdana, Red Cockscomb, Red Spinach, Rhamdana, Royal Grain, Smo
Drug: Eltrombopag
Brand names:
Promacta, Revolade
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Eltrombopag and Amaranth. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Amaranth Overview
Amaranth is a diverse group of plants found in lowlands, wastelands, and gardens, with some species yielding seeds used as pseudocereals or for oil. Others, like Amaranthus dubius and Amaranthus tricolor, have large leaves used as vegetables. Common medicinal varieties include Amaranthus roxburghianus and Amaranthus spinosus.
The whole amaranth plant is used medicinally. Its leaves contain some vitamin C and beta-carotene, with Amaranthus tricolor leaves also providing calcium, iron, and zinc. Amaranth seed oil is rich in unsaturated fatty acids (UFAs), including linoleic, alpha-linolenic, and oleic acids, along with saturated fatty acids (SFAs) like palmitic and stearic acids, in a 1:3 SFA to UFA ratio, and also contains squalene, tocopherols, and sterols.
Amaranth seeds, used as pseudocereals, are high in protein, vitamin E, antioxidant phenols, and minerals like iron. Amaranthus hypochondriacus seeds contain bioactive peptides like lunasin, vicilin, and 11S globulin. Amaranthus roxburghianus roots contain eugenol, benzene derivatives, and 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one, while Amaranthus spinosus bark contains betacyanins, quercetin, kaempferol, and amaranthoside.
Eltrombopag Overview
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Eltrombopag is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic immune thrombocytopenia (ITP; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood) and who have not been helped or cannot be treated with other treatments, including medications or surgery to remove the spleen. Eltrombopag is also used to increase the number of platelets in people who have hepatitis C (a viral infection that may damage the liver) so that they can begin and continue treatment with interferon (Peginterferon, Pegintron, others) and ribavirin (Rebetol). Eltrombopag is also used in combination with other medications to treat aplastic anemia (condition in which the body does not make enough new blood cells) in adults and children 2 years of age and older. It is also used to treat aplastic anemia in adults who have not been helped with other medications. Eltrombopag is used to increase the number of platelets enough to decrease the risk of bleeding in people with ITP or aplastic anemia, or to allow treatment with interferon and ribavirin in people with hepatitis C. However it is not used to increase the number of platelets to a normal level. Eltrombopag should not be used to treat people who have low numbers of platelets due to conditions other than ITP, hepatitis C, or aplastic anemia. Eltrombopag is in a class of medications called thrombopoietin receptor agonists. It works by causing the cells in the bone marrow to produce more platelets.
Amaranth - More Interactions
Amaranth interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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