Drug & supplement interaction

American Ivy + Benserazide, Levodopa

Benserazide, Levodopa brand names: Prolopa, Madopar.

No Known Interaction
The bottom line No known interaction

We found no known interaction between American Ivy and Benserazide, Levodopa in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

American Ivy and Benserazide, Levodopa

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Benserazide, Levodopa and American Ivy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

American Ivy safety at a glance

American Ivy overall Use caution Little safety data exists, and the berries are toxic, so use it cautiously and avoid eating any part of the plant.
Pregnancy Avoid There is not enough safety information, so it is best to avoid use during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the safer choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Benserazide, Levodopa and American Ivy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Benserazide, Levodopa

Interactions in our licensed database are recorded against drug classes, not just single drug names. Benserazide, Levodopa is filed under 5 classifications — including levodopa, dopamine agonists, seizure threshold lowering drugs. American Ivy has documented interactions with 1 drug class — the most serious being thiazide diuretics (moderate) — and none of Benserazide, Levodopa’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

American Ivy Does Interact With Other Medications

American Ivy has 56 moderate known drug interactions in our database — Benserazide, Levodopa isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against American Ivy

Covers the 2,830 medications we’ve checked against American Ivy. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Benserazide, Levodopa

This page covers American Ivy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Benserazide, Levodopa page lists 41 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Branched-chain Amino Acids (bcaa) (major), Cowhage (major), Indian Snakeroot (major) and Magnesium (major).

By severity: 8 major · 22 moderate · 11 minor.

From our pharmacist’s overview on the Benserazide, Levodopa page

“Benserazide with levodopa (Prolopa, Madopar) treats Parkinson disease, and because keeping levodopa levels steady is what keeps symptoms controlled, the 41 supplements on this page warrant genuine care, starting with the eight rated major. Nearly all of the serious ones work against the drug itself.”

Reviewed by 2 · Jul 18, 2026

Open the Benserazide, Levodopa interaction page

How much people look this up

Where American Ivy and Benserazide, Levodopa Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement American Ivy
Steady interest

#1,074 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Benserazide, Levodopa
Top 25%

#502 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. American Ivy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every American Ivy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The American Ivy and Benserazide, Levodopa records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About American Ivy

What is American Ivy?

American Ivy
  • Digestive upset
  • To stimulate sweating
  • Traditional tonic use
  • Skin and swelling complaints (topical folk use)

American Ivy (Virginia creeper) is mainly an ornamental climbing vine with a long history of folk use for digestion and sweating, but there is very little human evidence to support any health benefit. Its berries contain oxalic acid and are considered poisonous, and the plant can irritate the skin. Because safety data is limited, talk with your pharmacist or doctor before using it.

Parthenocissus quinquefolia · Vitaceae · Bark, leaves, and stems (berries are considered poisonous) · Dried bark, tinctures, teas; rarely sold as a standardized supplement

An interaction check asks whether these two react with each other — it does not ask whether American Ivy is a good idea for someone in your situation. Here is what our American Ivy record says about it on its own.

American Ivy: dosing

There is no established safe or effective dose for American Ivy. It is not a standardized supplement, so the strength of any product can vary a lot.If you choose to use a product that contains it, follow the directions on the label and do not exceed them. Never make a home preparation from the raw plant or its berries.

From our American Ivy monograph — the full record covers uses, side effects and every documented interaction.

Read the full American Ivy monograph & all interactions
Keep checking

Other Drugs & American Ivy

Browse every other medication we’ve checked against American Ivy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
56Moderate
0Minor
2,773No known interaction
Moderate

56 interactions

No interaction 2,773 drugs checked — show the list
Evidence & sources

American Ivy References

The 1 sources that drive our American Ivy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. American Ivy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Oxalates — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking American Ivy and Benserazide, Levodopa Together: Common Questions

Is it safe to take American Ivy with Benserazide, Levodopa?
We do not list a known interaction between American Ivy and Benserazide, Levodopa. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the American Ivy and Benserazide, Levodopa combination checked?
Interactions in our licensed database are recorded against drug classes. Benserazide, Levodopa is filed under 5 classifications, and American Ivy has documented interactions with 1 drug class — none of Benserazide, Levodopa's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does American Ivy interact with any other medications?
Yes. American Ivy has 56 documented drug interactions in our database — Benserazide, Levodopa is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Benserazide, Levodopa interact with any supplements?
Yes. Benserazide, Levodopa has documented interactions with 41 supplements in our database — American Ivy is not one of them. The Benserazide, Levodopa interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Benserazide, Levodopa and American Ivy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.