Canola Oil + Atorvastatin
Atorvastatin brand name: Atorvaliq.
We found no known interaction between Canola Oil and Atorvastatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Canola Oil and Atorvastatin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Atorvastatin and Canola Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Canola Oil at all — not against Atorvastatin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Canola Oil safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Canola Oil in Pregnancy & Breastfeeding
When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of using canola oil in medicinal amounts during pregnancy or lactation. Consuming canola oil, a source of alpha-linolenic acid, increases levels of this fatty acid in breast milk. While alpha-linolenic acid is likely safe during pregnancy and lactation when used in amounts typically found in food, it is unknown if it is safe in amounts exceeding those typically found in foods; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Atorvastatin Is Prescribed For, and What Canola Oil Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Atorvastatin is a prescription medicine with approved uses on its FDA label. Canola Oil is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Atorvastatin is prescribed for: Atorvastatin is used alongside a healthy diet to lower LDL ("bad") cholesterol, triglycerides (blood fats), and other harmful lipids, while raising HDL ("good") cholesterol. It treats primary hyperlipidemia (high cholesterol), mixed dyslipidemia (mixed abnormal blood fats), hypertriglyceridemia (high triglycerides), and inherited conditions such as heterozygous and homozygous familial hypercholesterolemia — including in children aged 10 and older. Beyond cholesterol control, atorvastatin is used to reduce the risk of heart attack, stroke, revascularization procedures, and angina (chest pain) in adults with coronary heart disease or multiple risk factors for it — including adults with type 2 diabetes who have risk factors for heart disease even without a confirmed heart disease diagnosis.
Canola Oil has been studied for:
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Diabetes studied, not established Canola Oil has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Canola Oil for diabetes
Preliminary clinical research in patients with type 2 diabetes shows that eating a canola oil-enriched bread supplement as part of a low glycemic load diet as an adjunct to oral hypoglycemic agents for 3 months reduces HbA1c by 0.47% compared with a reduction of 0.31% following intake of a wheat fiber bread as part of a whole-grain diet.
3 sources cited
- 98569. Jenkins DJ, Kendall CW, Vuksan V, et al. Effect of lowering the glycemic load with canola oil on glycemic control and cardiovascular risk factors: a randomized controlled trial. Diabetes Care. 2014;37(7):1806-14. PubMed
- 98584. Salar A, Faghih S, Pishdad GR. Rice bran oil and canola oil improve blood lipids compared to sunflower oil in women with type 2 diabetes: A randomized, single-blind, controlled trial. J Clin Lipidol. 2016;10(2):299-305. PubMed
- 101766. Atefi M, Pishdad GR, Faghih S. The effects of canola and olive oils on insulin resistance, inflammation and oxidative stress in women with type 2 diabetes: a randomized and controlled trial. J Diabetes Metab Disord. 2018;17(2):85-91. PubMed
-
Familial hypercholesterolemia studied, not established Canola Oil has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Canola Oil for familial hypercholesterolemia
A small clinical trial shows that using canola oil in place of all visible fat, at levels of 14-27 grams daily as part of a low-fat diet, for 13 weeks reduces levels of LDL cholesterol by 12.7% compared with baseline in children 6 years and up with familiar hypercholesterolemia. However, canola oil is no more effective than the same amount of sunflower oil.
1 source cited
- 98586. Negele L, Schneider B, Ristl R, et al. Effect of a low-fat diet enriched either with rapeseed oil or sunflower oil on plasma lipoproteins in children and adolescents with familial hypercholesterolaemia. Results of a pilot study. Eur J Clin Nutr. 2015;69(3 PubMed
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Atorvastatin on your own; if you are taking Canola Oil for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Canola Oil or Atorvastatin
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Canola Oil or Atorvastatin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Can I Take Ginkgo With Apixaban (Eliquis) and Atorvastatin? ›
- Is It Safe to Eat Pomegranate Seeds With Pravastatin? ›
- Is It Safe to Drink Motherwort Tea While Taking Atorvastatin? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Atorvastatin
This page covers Canola Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Atorvastatin page lists 181 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Apple (major), Beer (major), Grapefruit (major) and Green Tea (major).
By severity: 9 major · 136 moderate · 36 minor.
From our pharmacist’s overview on the Atorvastatin page
“Grapefruit is the entry to understand first. Atorvastatin (Atorvaliq) is cleared by an enzyme called CYP3A4, and grapefruit blocks that enzyme, letting statin levels climb along with the risk of side effects like muscle pain.”
Reviewed by 2 · Jul 18, 2026
Taking Canola Oil as Part of a Dietary Supplement Product? Check It for Interactions
We hold 33 real supplement products containing Canola Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Canola Oil. Even though Canola Oil itself has no known interaction with Atorvastatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Canola Oil and Atorvastatin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#832 of 1,452 supplements looked up here in the last 7 days
#18 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Canola Oil reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Canola Oil and Atorvastatin records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Canola Oil
What is Canola Oil?
- Heart health and cholesterol support
- Cooking and food preparation
- Source of unsaturated fats and omega-3 (ALA)
- Skin moisturizing (topical, traditional)
Canola oil is a common cooking oil pressed from the seeds of the canola plant, a type of rapeseed bred to be low in erucic acid. It is low in saturated fat and contains heart-friendly unsaturated fats, and replacing saturated fats with it may support healthy cholesterol. For most people it is safe as a food, but it is not a proven treatment for any disease.
Brassica napus · Brassicaceae · Seeds (oil pressed from the seeds) · Cooking oil, salad dressings, margarine, capsules (less common), and an ingredient in many processed foods
An interaction check asks whether these two react with each other — it does not ask whether Canola Oil is a good idea for someone in your situation. Here is what our Canola Oil record says about it on its own.
Canola Oil: dosing
There is no official medicinal dose for canola oil. As a food, it is simply used in cooking, baking, and salad dressings in normal recipe amounts. More is not better, since extra oil mainly adds calories.
From our Canola Oil monograph — the full record covers uses, side effects and every documented interaction.
About Atorvastatin
What Is Atorvastatin Used For?
Brand name: Atorvaliq
Atorvastatin is used alongside a healthy diet to lower LDL ("bad") cholesterol, triglycerides (blood fats), and other harmful lipids, while raising HDL ("good") cholesterol. It treats primary hyperlipidemia (high cholesterol), mixed dyslipidemia (mixed abnormal blood fats), hypertriglyceridemia (high triglycerides), and inherited conditions such as heterozygous and homozygous familial hypercholesterolemia — including in children aged 10 and older.
Beyond cholesterol control, atorvastatin is used to reduce the risk of heart attack, stroke, revascularization procedures, and angina (chest pain) in adults with coronary heart disease or multiple risk factors for it — including adults with type 2 diabetes who have risk factors for heart disease even without a confirmed heart disease diagnosis.
Other Drugs & Canola Oil
Browse every other medication we’ve checked against Canola Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Canola Oil against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Aspirin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Acetaminophen ›
- Escitalopram ›
- Tadalafil ›
- Clopidogrel ›
- Abemaciclib ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Ibuprofen ›
- Tirzepatide ›
- Methamphetamine ›
- Warfarin Sodium ›
- Semaglutide ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Bendamustine ›
- Amitriptyline ›
- Acyclovir ›
- Methotrexate ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Lamotrigine ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Gabapentin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Omeprazole ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Buspirone ›
- Naproxen ›
- Citalopram ›
- Ciprofloxacin ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Canola Oil list.
Canola Oil References
The 16 references that drive our Canola Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Crawford M, Galli C, Visioli F, et al. Role of Plant-Derived Omega-3 Fatty Acids in Human Nutrition. Ann Nutr Metab 2000;44:263-5. PubMed
- Connor WE. Alpha-linolenic acid in health and disease. Am J Clin Nutr 1999;69:827-8. PubMed
- Gibson RA, Makrides M. n-3 polyunsaturated fatty acid requirements of term infants. Am J Clin Nutr 2000;71:251S-5S. PubMed
- Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
- https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/. Accessed January 25, 2019.
- FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
- Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
- Kruse M, von Loeffelholz C, Hoffmann D, et al. Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men. Mol Nutr PubMed
- Jenkins DJ, Kendall CW, Vuksan V, et al. Effect of lowering the glycemic load with canola oil on glycemic control and cardiovascular risk factors: a randomized controlled trial. Diabetes Care. 2014;37(7):1806-14. PubMed
- Nigam P, Bhatt S, Misra A, et al. Effect of a 6-month intervention with cooking oils containing a high concentration of monounsaturated fatty acids (olive and canola oils) compared with control oil in male Asian Indians with nonalcoholic fatty liver disea
- Palomäki A, Pohjantähti-Maaroos H, Wallenius M, et al. Effects of dietary cold-pressed turnip rapeseed oil and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome. Lipids Health Dis. 2010;9:137. PubMed
- Francois CA, Connor SL, Wander RC, Connor WE. Acute effects of dietary fatty acids on the fatty acids of human milk. Am J Clin Nutr. 1998;67(2):301-8. PubMed
- Salar A, Faghih S, Pishdad GR. Rice bran oil and canola oil improve blood lipids compared to sunflower oil in women with type 2 diabetes: A randomized, single-blind, controlled trial. J Clin Lipidol. 2016;10(2):299-305. PubMed
- Negele L, Schneider B, Ristl R, et al. Effect of a low-fat diet enriched either with rapeseed oil or sunflower oil on plasma lipoproteins in children and adolescents with familial hypercholesterolaemia. Results of a pilot study. Eur J Clin Nutr. 2015;69(3 PubMed
- Atefi M, Pishdad GR, Faghih S. The effects of canola and olive oils on insulin resistance, inflammation and oxidative stress in women with type 2 diabetes: a randomized and controlled trial. J Diabetes Metab Disord. 2018;17(2):85-91. PubMed
- Raeisi-Dehkordi H, Amiri M, Humphries KH, Salehi-Abargouei A. The effect of canola oil on body weight and composition: A systematic review and meta-analysis of randomized controlled clinical trials. Adv Nutr. 2019;10(3):419-432. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Atorvastatin Is Linked to Lower Levels of 2 Nutrients
Natural Medicines records Atorvastatin as a medicine that can lower these. This is not an interaction with Canola Oil — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Atorvastatin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Canola Oil and Atorvastatin Together: Common Questions
Is it safe to take Canola Oil with Atorvastatin?
Are Canola Oil and Atorvastatin used for the same thing?
Does Atorvastatin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.