Drug & supplement interaction

Capers + Tavaborole

Tavaborole brand name: Kerydin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Capers and Tavaborole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Capers and Tavaborole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tavaborole and Capers in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Capers safety at a glance

Capers overall Use caution Generally safe as a food, but concentrated supplements are not well studied.
Pregnancy Use caution Food amounts are likely fine, but avoid medicinal or concentrated doses due to lack of safety data.
Breastfeeding Use caution Food amounts are likely fine, but concentrated supplements lack safety data, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tavaborole and Capers? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tavaborole

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tavaborole is filed under a single classification — topical drugs. Capers has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Tavaborole’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Capers Does Interact With Other Medications

Capers has 86 moderate known drug interactions in our database — Tavaborole isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Capers

Covers the 2,830 medications we’ve checked against Capers. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Capers and Tavaborole May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash reported in 9.1% of FDA reports for Tavaborole Additional detail

    Capers

    “Orally, capers seem to be well tolerated. No adverse effects have been reported in clinical research; however, a high-quality assessment of safety has not been conducted. Topically, capers can cause contact dermatitis.”

    Capers · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 96124. Huseini HF, Hasani-Rnjbar S, Nayebi N, et al. Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Complement Ther Med. 2013;21(5):447-52. PubMed
    2. 12742. Angelini G, Vena GA, Filotico R, et al. Allergic contact dermatitis from Capparis spinosa L. applied as wet compresses. Contact Dermatitis 1991;24:382-3.

    “Topically, capers can cause contact dermatitis.”

    Capers · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 12742. Angelini G, Vena GA, Filotico R, et al. Allergic contact dermatitis from Capparis spinosa L. applied as wet compresses. Contact Dermatitis 1991;24:382-3.

    Tavaborole

    Listed in the ADVERSE REACTIONS section of the FDA label for Tavaborole, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Tavaborole come from the ADVERSE REACTIONS section of its FDA label; effects for Capers come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 55 voluntary FDA FAERS reports for Tavaborole that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Tavaborole

This page covers Capers only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tavaborole page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Tavaborole page

“Tavaborole (Kerydin) is a solution you paint onto the toenail for fungal infections, and its supplement concerns stay right where you apply it. Only three ingredients have interactions on file, two rated moderate and one minor, and every one involves putting something else on the skin.”

Reviewed by 2 · Jul 18, 2026

Open the Tavaborole interaction page

One more smart check

Taking Capers as Part of a Dietary Supplement Product? Check It for Interactions

We hold 53 real supplement products containing Capers, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Capers. Even though Capers itself has no known interaction with Tavaborole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Capers and Tavaborole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Capers
Top half

#688 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tavaborole
Top half

#824 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Capers reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Capers and Tavaborole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Capers

What is Capers?

  • Digestive support
  • Antioxidant source
  • Blood sugar support
  • Anti-inflammatory
  • Skin and traditional tonic uses

Capers are the edible pickled flower buds of the Capparis spinosa shrub, used widely as food and in traditional medicine. They contain antioxidant plant compounds, but high-quality human studies on health benefits are limited, so the supplement claims remain largely unproven. As a food, capers are generally safe, but talk to your pharmacist or doctor before using concentrated extracts.

Capparis spinosa · Capparaceae · Flower buds, fruit, root bark, and leaves · Pickled or brined buds (food), capsules, extracts, dried powder

An interaction check asks whether these two react with each other — it does not ask whether Capers is a good idea for someone in your situation. Here is what our Capers record says about it on its own.

Capers: dosing

There is no established standard dose for capers as a supplement. As a food, people simply use them as a flavoring in small amounts.For capsules or extracts, follow the directions on the product label, since strengths vary widely between brands.

From our Capers monograph — the full record covers uses, side effects and every documented interaction.

Read the full Capers monograph & all interactions
Medication

About Tavaborole Topical

What Is Tavaborole Topical Used For?

Brand name: Kerydin

Tavaborole topical solution is used to treat onychomycosis of the toenails — a fungal infection of the toenails caused by Trichophyton rubrum or Trichophyton mentagrophytes, the two most common nail fungi.

It is applied directly to the toenail and is approved for adults and children 6 years of age and older.

Most-Reported Side Effects for Tavaborole

From FAERS, the FDA’s public side-effect reporting system (65 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Injection site pain 4 reports
Product dose omission in error 4 reports
Cough 3 reports
Product packaging quantity issue 3 reports
Pruritus 3 reports
See full Tavaborole Topical drug information
Keep checking

Other Drugs & Capers

Browse every other medication we’ve checked against Capers — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Capers page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Capers References

The 3 references that drive our Capers monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Angelini G, Vena GA, Filotico R, et al. Allergic contact dermatitis from Capparis spinosa L. applied as wet compresses. Contact Dermatitis 1991;24:382-3.
  2. Huseini HF, Hasani-Rnjbar S, Nayebi N, et al. Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Complement Ther Med. 2013;21(5):447-52. PubMed
  3. Vahid H, Bonakdaran S, Khorasani ZM, et al. Effect of Capparis spinosa extract on metabolic parameters in patients with type-2 diabetes: A randomized controlled trial. Endocr Metab Immune Disord Drug Targets. 2019;19(1):100-107. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Capers and Tavaborole Together: Common Questions

Is it safe to take Capers with Tavaborole?
We do not list a known interaction between Capers and Tavaborole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Capers and Tavaborole have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Capers and Tavaborole combination checked?
Interactions in our licensed database are recorded against drug classes. Tavaborole is filed under 1 classification, and Capers has documented interactions with 1 drug class — none of Tavaborole's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Capers interact with any other medications?
Yes. Capers has 86 documented drug interactions in our database — Tavaborole is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tavaborole interact with any supplements?
Yes. Tavaborole has documented interactions with 3 supplements in our database — Capers is not one of them. The Tavaborole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tavaborole and Capers?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.