Drug & supplement interaction

Carlina + Belladonna, Phenobarbital

Belladonna, Phenobarbital brand names: Bellophen, Susano.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Carlina and Belladonna, Phenobarbital in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Carlina and Belladonna, Phenobarbital

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Belladonna, Phenobarbital and Carlina in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Carlina at all — not against Belladonna, Phenobarbital, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Carlina safety at a glance

Carlina overall Use caution Human safety data are limited, so use carefully and only under guidance.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid No reliable safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Belladonna, Phenobarbital and Carlina? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Everything else you take

See Every Supplement That Interacts With Belladonna, Phenobarbital

This page covers Carlina only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Belladonna, Phenobarbital page lists 174 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Henbane (major).

By severity: 10 major · 143 moderate · 21 minor.

From our pharmacist’s overview on the Belladonna, Phenobarbital page

“Alcohol is the interaction I would flag first for anyone taking Belladonna and Phenobarbital (Bellophen, Susano). It carries a major, well-documented risk of deepened sedation, and it has plenty of company: 78 of the 174 supplements and herbs on file add drowsiness to a barbiturate that sedates on its own, kava among the worst of them.”

Reviewed by 2 · Jul 18, 2026

Open the Belladonna, Phenobarbital interaction page

One more smart check

Taking Carlina as Part of a Dietary Supplement Product? Check It for Interactions

We hold 38 real supplement products containing Carlina, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Carlina. Even though Carlina itself has no known interaction with Belladonna, Phenobarbital, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Carlina and Belladonna, Phenobarbital Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Carlina
Steady interest

#1,206 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Belladonna, Phenobarbital
Steady interest

#2,217 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Carlina is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Carlina reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Carlina and Belladonna, Phenobarbital records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Carlina

What is Carlina?

Carlina
  • Digestive upset and poor appetite
  • Diuretic (increasing urine flow)
  • Skin conditions when used topically
  • Antimicrobial folk remedy
  • Mild laxative or 'detox' use

Carlina (Carlina acaulis) is a thistle-like plant whose root has long been used in European folk medicine for digestive and skin complaints. Modern scientific evidence in humans is very limited, so its benefits are largely unproven. Because safety data are sparse, talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Carlina acaulis · Asteraceae · Root, and sometimes the flower heads and aerial parts · Dried root, tea/decoction, tincture, and traditional herbal preparations

An interaction check asks whether these two react with each other — it does not ask whether Carlina is a good idea for someone in your situation. Here is what our Carlina record says about it on its own.

Carlina: dosing

There is no well-established or standardized dose for Carlina. Traditional preparations were often made as a root tea or tincture, but the right amount, strength, and safe length of use have not been defined by good research.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Carlina monograph — the full record covers uses, side effects and every documented interaction.

Read the full Carlina monograph & all interactions
Keep checking

Other Drugs & Carlina

Browse every other medication we’ve checked against Carlina — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Carlina against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Carlina list.

See the full Carlina interactions page
See every supplement checked against Belladonna, Phenobarbital, ranked by severity
Evidence & sources

Carlina References

The 2 sources that drive our Carlina monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Carlina is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Carlina and Belladonna, Phenobarbital Together: Common Questions

Is it safe to take Carlina with Belladonna, Phenobarbital?
We do not list a known interaction between Carlina and Belladonna, Phenobarbital. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Belladonna, Phenobarbital interact with any supplements?
Yes. Belladonna, Phenobarbital has documented interactions with 174 supplements in our database — Carlina is not one of them. The Belladonna, Phenobarbital interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Carlina monograph Uses, safety profile, and every drug interaction in one place Belladonna, Phenobarbital supplement interactions Every supplement checked against Belladonna, Phenobarbital, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Belladonna, Phenobarbital and Carlina?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.