Drug & supplement interaction

Chuchuhuasi + Carbamazepine

Carbamazepine brand names: Tegretol, Tegretol XR, Equetro, Carbatrol, Carnexiv.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Chuchuhuasi and Carbamazepine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Chuchuhuasi and Carbamazepine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carbamazepine and Chuchuhuasi in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chuchuhuasi at all — not against Carbamazepine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chuchuhuasi safety at a glance

Chuchuhuasi overall Use caution It has a long history of traditional use but very little modern safety or quality testing, so use cautiously.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid it to be safe.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carbamazepine and Chuchuhuasi? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Carbamazepine’s Own FDA Label Lists

This is not an interaction — none of it involves Chuchuhuasi. These are the most notable effects listed in the ADVERSE REACTIONS section of Carbamazepine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Bone thinning Worth acting on
  • Trouble passing urine Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • A heart attack Worth acting on
  • Seizures Worth acting on mentioned in 5.5% of FDA reports for Carbamazepine
  • Blood clots Worth acting on
  • Hallucinations Worth acting on
  • Pancreatitis Worth acting on
  • Yellowing of the skin or eyes Worth acting on

Showing the 10 most notable of 50 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Carbamazepine. Read the label on DailyMed › Where a percentage is shown, it is the share of 38,334 voluntary FDA FAERS reports for Carbamazepine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Chuchuhuasi’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Chuchuhuasi side to compare — that is a limit of the record, not a statement that Chuchuhuasi has no side effects.

From our Q&A

Questions About Chuchuhuasi or Carbamazepine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chuchuhuasi or Carbamazepine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Carbamazepine

This page covers Chuchuhuasi only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carbamazepine page lists 284 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Asarabacca (major), Beer (major) and Gamma-hydroxybutyrate (ghb) (major).

By severity: 12 major · 235 moderate · 37 minor.

From our pharmacist’s overview on the Carbamazepine page

“Carbamazepine (Tegretol, Carbatrol, Equetro) only controls seizures and mood episodes when its blood level stays inside a tight window, and 284 supplement and herbal ingredients on file can disturb that balance, 12 of them rated major. Grapefruit can push carbamazepine levels up, St.”

Reviewed by 2 · Jul 18, 2026

Open the Carbamazepine interaction page

One more smart check

Taking Chuchuhuasi as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Chuchuhuasi, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chuchuhuasi. Even though Chuchuhuasi itself has no known interaction with Carbamazepine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chuchuhuasi and Carbamazepine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chuchuhuasi
Steady interest

#783 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carbamazepine
Top 25%

#387 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Chuchuhuasi is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chuchuhuasi reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Chuchuhuasi and Carbamazepine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chuchuhuasi

What is Chuchuhuasi?

  • Arthritis and joint pain
  • Back pain and muscle aches
  • Inflammation
  • Menstrual cramps
  • General tonic and energy
  • Digestive complaints

Chuchuhuasi is an Amazonian tree bark traditionally used for joint pain, inflammation, and as a general tonic. Solid human studies are lacking, so its benefits remain unproven, and you should talk to your pharmacist or doctor before trying it—especially if you are pregnant, breastfeeding, or taking other medicines.

Maytenus krukovii · Celastraceae · Bark (mainly the inner bark) and roots · Tinctures, capsules, dried bark for tea/decoction, liquid extracts, and bark soaked in aguardiente (local rum)

An interaction check asks whether these two react with each other — it does not ask whether Chuchuhuasi is a good idea for someone in your situation. Here is what our Chuchuhuasi record says about it on its own.

Chuchuhuasi: dosing

There is no established or standardized dose for chuchuhuasi. Because human studies are lacking, no one has determined a safe and effective amount.If you choose to try it, the safest approach is to follow the directions on the product label and not exceed them. Choose products from reputable companies that test for quality and purity.

From our Chuchuhuasi monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chuchuhuasi monograph & all interactions
Medication

About Carbamazepine

What Is Carbamazepine Used For?

Brand names: Tegretol, Tegretol XR, Equetro, Carbatrol, Carnexiv

Carbamazepine is used to treat certain types of seizures — including partial seizures, generalized tonic-clonic (grand mal) seizures, and mixed seizure patterns. It works best for those specific seizure types; it does not appear to control absence (petit mal) seizures.

It is also prescribed to relieve the intense facial pain of trigeminal neuralgia — a nerve condition that causes sudden, severe pain along the face. It is not a general painkiller and shouldn't be used for ordinary aches and pains.

Most-Reported Side Effects for Carbamazepine

From FAERS, the FDA’s public side-effect reporting system (38,334 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Toxicity to various agents 2,300 reports
Seizure 2,093 reports
Fall 1,963 reports
Dizziness 1,610 reports
Fatigue 1,525 reports
See full Carbamazepine drug information
Keep checking

Other Drugs & Chuchuhuasi

Browse every other medication we’ve checked against Chuchuhuasi — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Chuchuhuasi References

The 3 sources that drive our Chuchuhuasi monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Chuchuhuasi is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health (NCCIH) Source
  2. Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source
  3. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chuchuhuasi and Carbamazepine Together: Common Questions

Is it safe to take Chuchuhuasi with Carbamazepine?
We do not list a known interaction between Chuchuhuasi and Carbamazepine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Carbamazepine interact with any supplements?
Yes. Carbamazepine has documented interactions with 284 supplements in our database — Chuchuhuasi is not one of them. The Carbamazepine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Carbamazepine and Chuchuhuasi?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.