Drug & supplement interaction

Combretum Micranthum + Oliceridine

Oliceridine brand name: Olinvyk.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Combretum Micranthum and Oliceridine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Combretum Micranthum and Oliceridine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Oliceridine and Combretum Micranthum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Combretum Micranthum safety at a glance

Combretum Micranth... overall Use caution Used widely as a traditional tea, but human safety data are very limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Oliceridine and Combretum Micranthum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Oliceridine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Oliceridine is filed under 5 classifications — including qt interval-prolonging drugs, serotonergic drugs, serotonergic drugs. Combretum Micranthum has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), antihypertensive drugs (moderate) and diuretic drugs (moderate) — and none of Oliceridine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Combretum Micranthum Does Interact With Other Medications

Combretum Micranthum has 265 moderate known drug interactions in our database — Oliceridine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 265 No known interaction 2,565 (incl. Oliceridine)
Taking anything else?

Check Another of Your Medications Against Combretum Micranthum

Covers the 2,830 medications we’ve checked against Combretum Micranthum. Pick one to open its full report.

What to actually watch for

What Combretum Micranthum Itself Has Been Linked To

This is not an interaction — nothing below involves Oliceridine. It is the side-effect record for Combretum Micranthum on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Combretum Micranthum, this list is the first place to look.

  • Passing urine more often / Trouble sleeping Additional detail

    “Orally, nocturia resulting in insomnia has been reported rarely.”

    Combretum Micranthum · Natural Medicines adverse-effect record, reported in insomnia.

    1 source cited
    1. 106180. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
  • Stomach pain Additional detail

    “Orally, abdominal pain has been reported.”

    Combretum Micranthum · Natural Medicines adverse-effect record, reported in pain.

    2 sources cited
    1. 106180. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
    2. 106191. Seck SM, Doupa D, Dia DG, et al. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. J Hum Hypertens 2017;32(1):75-81. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Combretum Micranthum — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Oliceridine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Oliceridine column appears here.

Everything else you take

See Every Supplement That Interacts With Oliceridine

This page covers Combretum Micranthum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Oliceridine page lists 158 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: American Hellebore (major), Arsenic (major), Cesium (major), Ephedra (major) and Grapefruit (major).

By severity: 8 major · 118 moderate · 32 minor.

From our pharmacist’s overview on the Oliceridine page

“Oliceridine (Olinvyk) is an IV opioid used in hospitals for acute pain, and I treat its supplement list as one to respect, since eight of the 158 interactions on file rate major. Most of the list involves the liver enzymes that clear the drug: grapefruit can push oliceridine levels up and intensify side effects, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Oliceridine interaction page

How much people look this up

Where Combretum Micranthum and Oliceridine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Combretum Micranthum
Steady interest

#1,025 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Oliceridine
Steady interest

#2,228 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Combretum Micranthum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Combretum Micranthum and Oliceridine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Combretum Micranthum

What is Combretum Micranthum?

Combretum Micranthum
  • Digestive upset
  • Liver and gallbladder support
  • Fever
  • Weight management
  • Mild urinary or fluid retention
  • Traditional opium withdrawal aid

Combretum micranthum (kinkeliba) is a West African shrub whose leaves are brewed into a traditional tea for digestion, liver complaints, and fever. Solid human studies are lacking, so its benefits remain unproven, and people who are pregnant, breastfeeding, or have liver or kidney problems should be cautious and talk to a healthcare professional first.

Combretum micranthum · Combretaceae · Leaves (mainly), and sometimes stems and roots · Tea (herbal infusion or decoction), dried leaf powder, capsules, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Combretum Micranthum is a good idea for someone in your situation. Here is what our Combretum Micranthum record says about it on its own.

Combretum Micranthum: dosing

There is no established standardized dose for Combretum micranthum. Traditionally, a handful of dried leaves is steeped in hot water to make a tea, but the strength varies widely from one preparation to another.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Combretum Micranthum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Combretum Micranthum monograph & all interactions
Medication

About Oliceridine Injection

What Is Oliceridine Injection Used For?

Brand name: Olinvyk

Olinvyk (oliceridine) injection is approved for adults to manage acute pain that is severe enough to require an intravenous opioid analgesic. It is used only when alternative treatments are ineffective, not tolerated, or otherwise unable to provide adequate pain control.

Because of serious risks including addiction, misuse, overdose, and death, Olinvyk is reserved for situations where other pain management options are not sufficient. It is not intended for routine or chronic pain management.

See full Oliceridine Injection drug information
Keep checking

Other Drugs & Combretum Micranthum

Browse every other medication we’ve checked against Combretum Micranthum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
265Moderate
0Minor
2,564No known interaction
265 Moderate 2,564 No interaction
Moderate

265 interactions

Showing 60 of 265 moderate interactions — see all 265 on the Combretum Micranthum page.

No interaction 2,564 drugs checked — show the list

We also checked Combretum Micranthum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,564 medications checked with no known interaction — see the full Combretum Micranthum list.

See the full Combretum Micranthum interactions page
See every supplement checked against Oliceridine, ranked by severity
Evidence & sources

Combretum Micranthum References

The 4 references that drive our Combretum Micranthum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
  2. Kpemissi M, Potârniche AV, Lawson-Evi P, et al. Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and in-silico experiments. J Ethnopharmacol 2020;261:113133. PubMed
  3. Chika A, Bello SO. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats. J Ethnopharmacol 2010;129(1):34-7. PubMed
  4. Seck SM, Doupa D, Dia DG, et al. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. J Hum Hypertens 2017;32(1):75-81. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Combretum Micranthum and Oliceridine Together: Common Questions

Is it safe to take Combretum Micranthum with Oliceridine?
We do not list a known interaction between Combretum Micranthum and Oliceridine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Combretum Micranthum and Oliceridine combination checked?
Interactions in our licensed database are recorded against drug classes. Oliceridine is filed under 5 classifications, and Combretum Micranthum has documented interactions with 3 drug classes — none of Oliceridine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Combretum Micranthum interact with any other medications?
Yes. Combretum Micranthum has 265 documented drug interactions in our database — Oliceridine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Oliceridine interact with any supplements?
Yes. Oliceridine has documented interactions with 158 supplements in our database — Combretum Micranthum is not one of them. The Oliceridine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Combretum Micranthum monograph Uses, safety profile, and every drug interaction in one place Oliceridine Injection drug information The full plain-English guide to this medication Oliceridine supplement interactions Every supplement checked against Oliceridine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Oliceridine and Combretum Micranthum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.