Drug & supplement interaction

Dash Diet + Trazodone

Trazodone brand names: Desyrel, Oleptro.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Dash Diet and Trazodone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Dash Diet and Trazodone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Trazodone and Dash Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Dash Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Dash Diet at all — not against Trazodone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Dash Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dash Diet safety at a glance

Dash Diet overall Generally safe For most people DASH is a safe, balanced way of eating that supports heart health.
Pregnancy Possibly Safe When used appropriately, short-term. DASH diets have been used with apparent safety during pregnancy for 4-12 weeks. A modified DASH diet called MAMA-DASH, with... Read the full pregnancy detail
Breastfeeding Possibly Safe When used appropriately while breastfeeding for up to 6 months. The DASH diet is a balanced diet that is not expected to be harmful during breastfeeding. Observ... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Trazodone and Dash Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Trazodone’s Own FDA Label Lists

This is not an interaction — none of it involves Dash Diet. These are the most notable effects listed in the ADVERSE REACTIONS section of Trazodone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you follow Dash Diet and take the medicine. 8 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Serotonin syndrome Worth acting on
  • Thoughts of self-harm Worth acting on
  • Low sodium Worth acting on
  • Fainting Worth acting on
  • Confusion Worth acting on
  • Raised blood pressure Worth acting on
  • Bleeding or bruising Worth acting on
  • Weight gain
  • Weight loss

Showing the 10 most notable of 25 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Trazodone. Read the label on DailyMed › Dash Diet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Dash Diet side to compare — that is a limit of the record, not a statement that Dash Diet has no side effects.

Special populations

Dash Diet in Pregnancy & Breastfeeding

Pregnancy Possibly Safe

When used appropriately, short-term. DASH diets have been used with apparent safety during pregnancy for 4-12 weeks. A modified DASH diet called MAMA-DASH, with adequate nutrition and calories for pregnancy, has been used for 20 weeks without reports of adverse events.

Lactation Possibly Safe

When used appropriately while breastfeeding for up to 6 months. The DASH diet is a balanced diet that is not expected to be harmful during breastfeeding. Observational research in exclusively breastfed infants has found that high adherence to the DASH diet for 4-6 months while breastfeeding is not associated with changes in infant weight, height, or head circumference when compared with low adherence to the DASH diet.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Trazodone Is Prescribed For, and What Dash Diet Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Trazodone is a prescription medicine with approved uses on its FDA label. Dash Diet is an eating pattern: what follows is what researchers have looked at it for, and how strong that evidence is.

Trazodone is prescribed for: Trazodone is approved to treat major depressive disorder (MDD) in adults. This applies to trazodone hydrochloride tablets (brands including Trazodone HCl and Trazodone Hydrochloride) and to Raldesy, the oral solution form of trazodone. It is not approved for use in children or adolescents.

Dash Diet has been studied for:

  • Depression studied, not established Dash Diet has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Dash Diet for depression

    Observational research has found that following the DASH diet seems to be associated with a reduced risk of depression.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Trazodone on your own; if you are taking Dash Diet for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Dash Diet or Trazodone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Dash Diet or Trazodone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Trazodone

This page covers Dash Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Trazodone page lists 197 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Lithium (major) and Siberian Cocklebur (major).

By severity: 7 major · 151 moderate · 39 minor.

From our pharmacist’s overview on the Trazodone page

“St. John's wort tops my worry list with trazodone (Desyrel, Oleptro), the antidepressant many people also take for sleep.”

Reviewed by 2 · Jul 18, 2026

Open the Trazodone interaction page

How much people look this up

Where Dash Diet and Trazodone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dash Diet
Top half

#675 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Trazodone
Top 10%

#172 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dash Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Dash Diet and Trazodone records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Dash Diet

What is Dash Diet?

  • High blood pressure
  • Heart health
  • Lowering cholesterol
  • Weight management
  • Healthy eating pattern

The DASH (Dietary Approaches to Stop Hypertension) diet is an eating plan rich in fruits, vegetables, whole grains, and low-fat dairy, with less salt, red meat, and added sugar. It is one of the best-studied diets for lowering blood pressure and is widely recommended by doctors and dietitians. It is a food-based lifestyle plan, not a pill or supplement.

Eating pattern (whole-food diet plan)

An interaction check asks whether these two react with each other — it does not ask whether Dash Diet is a good idea for someone in your situation. Here is what our Dash Diet record says about it on its own.

Dash Diet: dosing

There is no pill or standardized "dose" for DASH, since it is an eating pattern rather than a supplement. Instead, the plan suggests target servings each day from food groups like vegetables, fruits, grains, dairy, lean protein, and a limited amount of fats and sweets.Sodium goals are usually set at a moderate level, and there is a lower-sodium version that may lower blood pressure even more. The exact amounts depend on your calorie needs, age, and health goals.A registered dietitian or your pharmacist can help you tailor the plan to your needs. Free DASH guides are also available from the NIH and National Heart, Lung, and Blood Institute.

From our Dash Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dash Diet monograph & all interactions
Medication

About Trazodone

What Is Trazodone Used For?

Brand names: Desyrel, Oleptro

Trazodone is approved to treat major depressive disorder (MDD) in adults. This applies to trazodone hydrochloride tablets (brands including Trazodone HCl and Trazodone Hydrochloride) and to Raldesy, the oral solution form of trazodone.

It is not approved for use in children or adolescents.

See full Trazodone drug information
Keep checking

Other Drugs & Dash Diet

Browse every other medication we’ve checked against Dash Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Dash Diet against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Dash Diet list.

See the full Dash Diet interactions page
See every supplement checked against Trazodone, ranked by severity
Evidence & sources

Dash Diet References

The 3 references that drive our Dash Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Van Horn L, Peaceman A, Kwasny M, et al. Dietary Approaches to Stop Hypertension Diet and Activity to Limit Gestational Weight: Maternal Offspring Metabolics Family Intervention Trial, a Technology Enhanced Randomized Trial. Am J Prev Med. 2018;55(5):603- PubMed
  2. Li S, Gan Y, Chen M, et al. Effects of the dietary approaches to stop hypertension (DASH) on pregnancy/neonatal outcomes and maternal glycemic control: A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med. 2020 Nov;54:1 PubMed
  3. Jahangir F, Daneshzad E, Moradi M, Maraci MR, Surkan PJ, Azadbakht L. No association between infant growth and adherence to the dietary approaches to stop hypertension (DASH) diet in lactating women. Nutr Health 2022. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Dash Diet While Taking Trazodone: Common Questions

Is it safe to follow Dash Diet while taking Trazodone?
We do not list a known interaction between Dash Diet and Trazodone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Dash Diet and Trazodone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Dash Diet in each. That is a conversation for your prescriber, especially if Trazodone is being adjusted to a target.
Does Trazodone interact with any supplements?
Yes. Trazodone has documented interactions with 197 supplements in our database — Dash Diet is not one of them. The Trazodone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Dash Diet monograph Uses, safety profile, and every drug interaction in one place Trazodone drug information The full plain-English guide to this medication Trazodone supplement interactions Every supplement checked against Trazodone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Trazodone and Dash Diet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.