Drug & supplement interaction

Delta-9-tetrahydrocannabinol (thc) + Cefaclor

Cefaclor brand names: Ceclor CD, Ceclor.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Delta-9-tetrahydrocannabinol (thc) and Cefaclor in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Cefaclor states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Delta-9-tetrahydrocannabinol (thc) and Cefaclor

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cefaclor and Delta-9-tetrahydrocannabinol (thc) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Delta-9-tetrahydrocannabinol (thc) safety at a glance

Delta-9-tetrahydro... overall Use caution THC is psychoactive, can impair judgment and coordination, and its legal status varies; use only under medical supervision.
Pregnancy Unsafe When used orally or inhaled. Cannabinoid constituents in cannabis, such as THC, pass through the placenta and can reduce fetal growth and increase the risk for... Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally or inhaled. THC is concentrated and excreted in breast milk for longer than 6 weeks after cessation of use; prolonged use of cannabis containin... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cefaclor and Delta-9-tetrahydrocannabinol (thc)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Cefaclor

Interactions in our licensed database are recorded against drug classes, not just single drug names. Cefaclor is filed under 6 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, antibiotic drugs. Delta-9-tetrahydrocannabinol (thc) has documented interactions with 16 drug classes — the most serious being alcohol (ethanol) (moderate), anesthesia (moderate) and anticoagulant/antiplatelet drugs (moderate) — and none of Cefaclor’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Delta-9-tetrahydrocannabinol (thc) Does Interact With Other Medications

Delta-9-tetrahydrocannabinol (thc) has 762 moderate, 336 minor known drug interactions in our database — Cefaclor isn’t one of them. If you take anything else, check it against the full list below.

Moderate 762 Minor 336 No known interaction 1,732 (incl. Cefaclor)
Taking anything else?

Check Another of Your Medications Against Delta-9-tetrahydrocannabinol (thc)

Covers the 2,830 medications we’ve checked against Delta-9-tetrahydrocannabinol (thc). Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Delta-9-tetrahydrocannabinol (thc) and Cefaclor May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 7 of them are worth acting on rather than waiting out — marked below.

  • Fainting Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “Orally, edible cannabis products containing 50 mg or more of THC have been associated with myocardial infarction and ventricular arrhythmia. In a case report, a 2-year-old boy developed bradycardia with first-degree atrioventricular block which lasted 12 hours, after accidentally consuming an unknown number of cannabis gummies containing THC.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in arrhythmia.

    6 sources cited
    1. 103796. Monte AA, K Shelton SK, Mills E., Acute Illness Associated With Cannabis Use, by Route of Exposure: An Observational Study. Ann Intern Med. 2019 Apr 16;170(8):531-537. PubMed
    2. 110237. Idris I, Diez JR, Assoku BA, Beker S. Accidental ingestion of tetrahydrocannabinol-laced gummies causing bradycardia and first-degree atrioventricular block in a pediatric patient: A case report. Cureus 2022;14(7):e26826. PubMed
    3. 110258. Highlights of prescribing information. MARINOL (dronabinol) capsules, for oral use, CIII. August 2017. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018651s029lbl.pdf. Accessed April 10, 2023.
    4. 110259. Cesamet (nabilone) capsules for oral administration. May 2006. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018677s011lbl.pdf. Accessed April 10, 2023.
    5. 110231. Maharaj N, Swarath S, Seecheran R, Seecheran V, Seecheran NA. Suspected cannabis vaping-induced pericardial effusion. J Investig Med High Impact Case Rep 2022;10:23247096221140251. PubMed
    6. 61759. Rog, D. J., Nurmikko, T. J., Friede, T., and Young, C. A. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 9-27-2005;65(6):812-819. PubMed

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Confusion Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “Cannabinoids such as THC can increase anxiety, confusion, depressed mood, and hallucinations, and reduce motivation. Cannabis dabbing, the making of a waxy product with extremely high concentrations of THC, is thought to increase the risk of anxiety, agitation, paranoia, and psychosis.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in anxiety.

    6 sources cited
    1. 96384. Whiting PF, Wolff RF, Deshpande S, et al. Cannabinoids for medical use: A systematic review and meta-analysis. JAMA. 2015;313(24):2456-73. PubMed
    2. 110252. Murray CH, Glazer JE, Lee R, Nusslock R, de Wit H. ?9-THC reduces reward-related brain activity in healthy adults. Psychopharmacology (Berl) 2022;239(9):2829-2840. PubMed
    3. 110257. Pisani S, McGoohan K, Velayudhan L, Bhattacharyya S. Safety and Tolerability of Natural and Synthetic Cannabinoids in Older Adults: A Systematic Review and Meta-Analysis of Open-Label Trials and Observational Studies. Drugs Aging 2021;38(10):887-910. PubMed
    4. 108341. Mullins MF. Cannabis dabbing: An emerging trend. Nursing. 2021;51(5):46-50.
    5. 91914. Hancock-Allen JB, Barker L, VanDyke M, Holmes DB. Notes from the Field: Death Following Ingestion of an Edible Marijuana Product--Colorado, March 2014. MMWR Morb Mortal Wkly Rep. 2015;64(28):771-2. PubMed
    6. 103796. Monte AA, K Shelton SK, Mills E., Acute Illness Associated With Cannabis Use, by Route of Exposure: An Observational Study. Ann Intern Med. 2019 Apr 16;170(8):531-537. PubMed

    “Meta-analyses of clinical and observational research involving adults with a mean age of at least 50 years show that increasing the dose of natural or synthetic THC in cannabinoid-based medicines is associated with a modest increase in overall adverse effects, including dizziness/light-headedness, mobility/balance/coordination difficulties, somnolence, disorientation, memory impairment, fatigue, and euphoria.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in cluster headache.

    6 sources cited
    1. 105559. Velayudhan L, McGoohan K, Bhattacharyya S. Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis. PLoS Med. 2021;18(3):e1003524. PubMed
    2. 110257. Pisani S, McGoohan K, Velayudhan L, Bhattacharyya S. Safety and Tolerability of Natural and Synthetic Cannabinoids in Older Adults: A Systematic Review and Meta-Analysis of Open-Label Trials and Observational Studies. Drugs Aging 2021;38(10):887-910. PubMed
    3. 110249. Zubcevic K, Petersen M, Bach FW, et al. Oral capsules of tetra-hydro-cannabinol (THC), cannabidiol (CBD) and their combination in peripheral neuropathic pain treatment. Eur J Pain 2022.
    4. 61759. Rog, D. J., Nurmikko, T. J., Friede, T., and Young, C. A. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 9-27-2005;65(6):812-819. PubMed
    5. 61764. Perras, C. Sativex for the management of multiple sclerosis symptoms. Issues Emerg.Health Technol. 2005;(72):1-4.
    6. 61820. Rog, D. J., Nurmikko, T. J., and Young, C. A. Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. Clin Ther. 2007;29(9):2068-2079.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • A severe skin reaction Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “Cannabis containing THC has been associated with dermatologic adverse effects, including erythema multiforme-like recurrent drug eruption. However, it is unclear if these adverse effects are due to the THC constituent of cannabis, other constituents, or a combination.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in erythema.

    1 source cited
    1. 110258. Highlights of prescribing information. MARINOL (dronabinol) capsules, for oral use, CIII. August 2017. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018651s029lbl.pdf. Accessed April 10, 2023.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Kidney problems Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “A case of acute kidney injury has been reported in a 94-year-old adult after consumption of cannabis containing THC; it was likely caused by pre-existing mild dehydration related to a lack of fluid intake, followed by cannabis-induced diarrhea.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 111071. Moussa MK, Hall MAK, Akwe J. Cannabis-induced acute encephalopathy in a 94-year-old woman due to family administration of cannabidiol (CBD) products: A case report. Cureus 2023;15(4):e37927.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Hives / An allergic reaction Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “Taking a prescription drug called dronabinol (Marinol), a synthetic form of THC, has been associated with hypersensitivity reactions, including lip swelling and oral lesions, skin hives, rash, or flushing, or throat tightness.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in urinary tract infections (utis).

    2 sources cited
    1. 110258. Highlights of prescribing information. MARINOL (dronabinol) capsules, for oral use, CIII. August 2017. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018651s029lbl.pdf. Accessed April 10, 2023.
    2. 110257. Pisani S, McGoohan K, Velayudhan L, Bhattacharyya S. Safety and Tolerability of Natural and Synthetic Cannabinoids in Older Adults: A Systematic Review and Meta-Analysis of Open-Label Trials and Observational Studies. Drugs Aging 2021;38(10):887-910. PubMed

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • A higher chance of infection Worth acting on Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    Recorded for Delta-9-tetrahydrocannabinol (thc) in the same Natural Medicines adverse-effect record shown under Hives / An allergic reaction above.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Sore throat Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    “Using a specific oromucosal spray that contains THC 2.7 mg and cannabidiol 2.5 mg per actuation (Sativex, GW Pharmaceuticals) may cause pharyngitis, hoarseness, and throat irritation.”

    Delta-9-tetrahydrocannabinol (thc) · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 61759. Rog, D. J., Nurmikko, T. J., Friede, T., and Young, C. A. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 9-27-2005;65(6):812-819. PubMed

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Sweating Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    Recorded for Delta-9-tetrahydrocannabinol (thc) in the same Natural Medicines adverse-effect record shown under Confusion above.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

  • Low blood pressure Additional detail

    Delta-9-tetrahydrocannabinol (thc)

    Recorded for Delta-9-tetrahydrocannabinol (thc) in the same Natural Medicines adverse-effect record shown under Fainting above.

    Cefaclor

    Listed in the ADVERSE REACTIONS section of the FDA label for Cefaclor. Read the label on DailyMed ›

Showing the 10 most notable of 24 shared effects — ranked by how unusual each one is, not just whether both lists mention it.

Reported for Delta-9-tetrahydrocannabinol (thc) but not commonly for Cefaclor: raised blood pressure, an irregular heartbeat, a heart attack and memory problems.

Effects for Cefaclor come from the ADVERSE REACTIONS section of its FDA label; effects for Delta-9-tetrahydrocannabinol (thc) come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Delta-9-tetrahydrocannabinol (thc) in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally or inhaled. Cannabinoid constituents in cannabis, such as THC, pass through the placenta and can reduce fetal growth and increase the risk for preterm birth. Cannabis use during pregnancy is also associated with placental abruption, stillbirth, preterm delivery, fetal abnormalities, low birth weight, small for gestational age, increased need for neonatal intensive care, and childhood leukemia. Prenatal cannabis use has also been associated with long-term adverse developmental effects in the offspring, such as worsened cognition, increased risk for neurodevelopmental disorders such as autism spectrum disorder, and increased risk for psychological issues during adolescence. Due to the observational nature of these studies, it is unclear if cannabis causes these adverse effects. Umbilical artery Doppler scans also show that cannabis use can increase placental vascular resistance. Cannabis use during pregnancy has been associated with increased risk of anemia and hypertension in the mother. Although the safety of pure THC has not been investigated during pregnancy, it is likely that THC is at least partially responsible for these safety concerns. The rate of negative fetal outcomes due to cannabis use during pregnancy may have been previously underestimated due to reliance on maternal self-reporting of use. Recent programs requiring maternal urine toxicology testing have increased awareness of maternal cannabis use and suggest that negative fetal outcomes occur more frequently than previously recorded.

Lactation Likely Unsafe

When used orally or inhaled. THC is concentrated and excreted in breast milk for longer than 6 weeks after cessation of use; prolonged use of cannabis containing THC during lactation has been associated with delayed motor development. Observational research in mothers who successfully abstained from cannabis use for 6 weeks (confirmed by a negative THC urine screen) after smoking cannabis prenatally at least twice weekly, found that THC levels in breastmilk increased during the first 2 weeks of abstinence and then decreased but remained detectable at 6 weeks. For patients planning to breastfeed, recommend abstaining from THC use prenatally and during lactation. Recommendations to discard breastmilk until THC levels are undetectable are not practical, as this may take more than 6 weeks.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Cefaclor Products Have a Food Rule — Delta-9-tetrahydrocannabinol (thc) Should Not Break It

At least one FDA label for a product containing Cefaclor says to take it with food. If you take Delta-9-tetrahydrocannabinol (thc) on an empty stomach out of habit, keep them separate — and take Cefaclor with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Cefaclor products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

DOSAGE AND ADMINISTRATION The absorption of cefaclor extended-release tablets is enhanced when it is administered with food.

From the Dosage and Administration section of the FDA label we read for Cefaclor — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Cefaclor

This page covers Delta-9-tetrahydrocannabinol (thc) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cefaclor page lists 60 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 46 moderate · 11 minor.

From our pharmacist’s overview on the Cefaclor page

“The entries worth understanding before any others on this cefaclor (Ceclor) page are the kidney risks and charcoal. Cefaclor is a cephalosporin antibiotic, typically a short course for ear, sinus, throat, or skin infections, and two herbs here, Siberian cocklebur and asarabacca, can damage the kidneys on their own, so pairing either wi…”

Reviewed by 2 · Jul 18, 2026

Open the Cefaclor interaction page

How much people look this up

Where Delta-9-tetrahydrocannabinol (thc) and Cefaclor Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Delta-9-tetrahydrocannabinol (thc)
Top half

#513 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cefaclor
Top 10%

#219 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Delta-9-tetrahydrocannabinol (thc) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Delta-9-tetrahydrocannabinol (thc) and Cefaclor records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Delta-9-tetrahydrocannabinol (thc)

What is Delta-9-tetrahydrocannabinol (thc)?

Delta-9-tetrahydrocannabinol (thc)
  • Chronic or nerve pain
  • Nausea and vomiting from chemotherapy
  • Appetite loss and weight loss
  • Muscle spasticity
  • Sleep problems
  • Anxiety and stress

THC is the main mind-altering compound in cannabis and is best known for causing a 'high.' A prescription form (dronabinol) is approved for chemotherapy-related nausea and appetite loss, but for most other uses the evidence is mixed or limited, and THC can impair thinking and driving. It should be avoided in pregnancy and breastfeeding and used only with medical guidance.

Cannabis sativa · Cannabaceae · Flowering tops and resin of the cannabis plant (THC is a single cannabinoid isolated or concentrated from these) · Prescription oral capsules (dronabinol), oral oil/solution, dried flower, vape and concentrate products (such as butane hash oil/dabs), tinctures, and edibles

An interaction check asks whether these two react with each other — it does not ask whether Delta-9-tetrahydrocannabinol (thc) is a good idea for someone in your situation. Here is what our Delta-9-tetrahydrocannabinol (thc) record says about it on its own.

Delta-9-tetrahydrocannabinol (thc): dosing

There is no single standard dose of THC for general use, and the right amount varies widely from person to person based on tolerance, the product, and the reason for use. Concentrated products contain much more THC than dried flower, which makes accidental overuse easy.For prescription products such as dronabinol, a doctor sets the dose.

From our Delta-9-tetrahydrocannabinol (thc) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Delta-9-tetrahydrocannabinol (thc) monograph & all interactions
Medication

About Cefaclor

What Is Cefaclor Used For?

Brand names: Ceclor CD, Ceclor

Cefaclor treats a range of bacterial infections. Cefaclor capsules and oral suspension are used for ear infections (otitis media), lower respiratory tract infections including pneumonia, strep throat and tonsillitis, urinary tract infections (including kidney infections and bladder infections), and skin and skin structure infections.

Cefaclor extended-release tablets are approved for a narrower set of uses in adults: acute bacterial flare-ups of chronic bronchitis, strep throat and tonsillitis, and uncomplicated skin and skin structure infections. Not all formulations are approved for the same conditions, so the form matters.

See full Cefaclor drug information
Keep checking

Other Drugs & Delta-9-tetrahydrocannabinol (thc)

Browse every other medication we’ve checked against Delta-9-tetrahydrocannabinol (thc) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
762Moderate
336Minor
1,731No known interaction
762 Moderate 336 Minor 1,731 No interaction
Moderate

762 interactions

Showing 60 of 762 moderate interactions — see all 762 on the Delta-9-tetrahydrocannabinol (thc) page.

Minor

336 interactions

Showing 60 of 336 minor interactions — see all 336 on the Delta-9-tetrahydrocannabinol (thc) page.

No interaction 1,731 drugs checked — show the list

We also checked Delta-9-tetrahydrocannabinol (thc) against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,731 medications checked with no known interaction — see the full Delta-9-tetrahydrocannabinol (thc) list.

See the full Delta-9-tetrahydrocannabinol (thc) interactions page
See every supplement checked against Cefaclor, ranked by severity
Evidence & sources

Delta-9-tetrahydrocannabinol (thc) References

The 76 references that drive our Delta-9-tetrahydrocannabinol (thc) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
  3. Tyrey L. Delta 9-Tetrahydrocannabinol: a potent inhibitor of episodic luteinizing hormone secretion. J Pharmacol Exp Ther 1980;213:306-8. DOI
  4. Briggs GB, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 1998.
  5. Marinol Prescribing Information. Solvay Pharmaceuticals, Rev March 2008. Available at: http://www.solvaypharmaceuticals-us.com/static/wma/pdf/1/3/2/5/0/004InsertText500012RevMar2008.pdf (Accessed 2 July 2009).
  6. Yamreudeewong W, Wong HK, Brausch LM, Pulley KR. Probable interaction between warfarin and marijuana smoking. Ann Pharmacother 2009;43:1347-53. PubMed
  7. Pellinen, P., Honkakoski, P., Stenback, F., Niemitz, M., Alhava, E., Pelkonen, O., Lang, M. A., and Pasanen, M. Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors. Eur.J Pharmacol 1-3-1994;2 PubMed
  8. Johnson, E. M. Substance abuse and women's health. Public Health Rep. 1987;102(4 Suppl):42-48.
  9. Astley, S. J. and Little, R. E. Maternal marijuana use during lactation and infant development at one year. Neurotoxicol.Teratol. 1990;12(2):161-168. PubMed
  10. Levy, R., Schurr, A., Nathan, I., Dvilanski, A., and Livne, A. Impairment of ADP-induced platelet aggregation by hashish components. Thromb.Haemost. 12-31-1976;36(3):634-640. DOI
  11. Sheweita, S. A. Narcotic drugs change the expression of cytochrome P450 2E1 and 2C6 and other activities of carcinogen-metabolizing enzymes in the liver of male mice. Toxicology 9-30-2003;191(2-3):133-142. PubMed
  12. Rog, D. J., Nurmikko, T. J., Friede, T., and Young, C. A. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 9-27-2005;65(6):812-819. PubMed
  13. Perras, C. Sativex for the management of multiple sclerosis symptoms. Issues Emerg.Health Technol. 2005;(72):1-4.
  14. Zhu, H. J., Wang, J. S., Markowitz, J. S., Donovan, J. L., Gibson, B. B., Gefroh, H. A., and Devane, C. L. Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana. J Pharmacol Exp.Ther. 2006;317(2):850-857. PubMed
  15. Holland, M. L., Panetta, J. A., Hoskins, J. M., Bebawy, M., Roufogalis, B. D., Allen, J. D., and Arnold, J. C. The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. Biochem.Pharmacol 4-14-2006;71(8):1146-115 PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Delta-9-tetrahydrocannabinol (thc) and Cefaclor Together: Common Questions

Is it safe to take Delta-9-tetrahydrocannabinol (thc) with Cefaclor?
We do not list a known interaction between Delta-9-tetrahydrocannabinol (thc) and Cefaclor. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Delta-9-tetrahydrocannabinol (thc) and Cefaclor have any of the same side effects?
Yes — our sources link each of them separately to 10 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Delta-9-tetrahydrocannabinol (thc) and Cefaclor at the same time of day?
At least one FDA label for a product containing Cefaclor says to take it with food. If you take Delta-9-tetrahydrocannabinol (thc) on an empty stomach out of habit, keep them separate and take Cefaclor with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Cefaclor products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Delta-9-tetrahydrocannabinol (thc) and Cefaclor combination checked?
Interactions in our licensed database are recorded against drug classes. Cefaclor is filed under 6 classifications, and Delta-9-tetrahydrocannabinol (thc) has documented interactions with 16 drug classes — none of Cefaclor's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Delta-9-tetrahydrocannabinol (thc) interact with any other medications?
Yes. Delta-9-tetrahydrocannabinol (thc) has 1,098 documented drug interactions in our database — Cefaclor is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Cefaclor interact with any supplements?
Yes. Cefaclor has documented interactions with 60 supplements in our database — Delta-9-tetrahydrocannabinol (thc) is not one of them. The Cefaclor interaction page linked on this page lists every one, ranked by severity.

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Delta-9-tetrahydrocannabinol (thc) monograph Uses, safety profile, and every drug interaction in one place Cefaclor drug information The full plain-English guide to this medication Cefaclor supplement interactions Every supplement checked against Cefaclor, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 76 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.