Drug & supplement interaction

Diacylglycerol + Cephalexin

Cephalexin brand names: Keflex, Keftab, Cephalex, Lexin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Diacylglycerol and Cephalexin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Diacylglycerol and Cephalexin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cephalexin and Diacylglycerol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Diacylglycerol at all — not against Cephalexin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Diacylglycerol safety at a glance

Diacylglycerol overall Use caution Considered a normal dietary fat, but health-benefit claims are unproven and one commercial product faced a contaminant recall.
Pregnancy Likely Safe When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amou... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amou... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cephalexin and Diacylglycerol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Cephalexin’s Own FDA Label Lists

This is not an interaction — none of it involves Diacylglycerol. These are the most notable effects listed in the ADVERSE REACTIONS section of Cephalexin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on

Showing the 10 most notable of 23 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Cephalexin. Read the label on DailyMed › Diacylglycerol’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Diacylglycerol side to compare — that is a limit of the record, not a statement that Diacylglycerol has no side effects.

Special populations

Diacylglycerol in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amounts during pregnancy and lactation.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Diacylglycerol or Cephalexin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Diacylglycerol or Cephalexin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Cephalexin

This page covers Diacylglycerol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cephalexin page lists 61 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 47 moderate · 11 minor.

From our pharmacist’s overview on the Cephalexin page

“Cephalexin (Keflex) is one of the most commonly prescribed oral antibiotics, usually for skin and urinary infections, and its supplement list warrants genuine care rather than a quick skim. Three of the 61 ingredients on file rate major.”

Reviewed by 2 · Jul 18, 2026

Open the Cephalexin interaction page

One more smart check

Taking Diacylglycerol as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Diacylglycerol, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Diacylglycerol. Even though Diacylglycerol itself has no known interaction with Cephalexin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Diacylglycerol and Cephalexin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Diacylglycerol
Steady interest

#1,382 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cephalexin
Top 5%

#76 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Diacylglycerol is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Diacylglycerol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Diacylglycerol and Cephalexin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Diacylglycerol

What is Diacylglycerol?

  • Weight management
  • Reducing body fat
  • Lowering blood triglycerides
  • Healthy cooking oil substitute

Diacylglycerol (DAG) is a type of fat found naturally in small amounts in many edible oils and was once sold as a specialty cooking oil marketed for weight and fat management. Evidence for meaningful weight-loss benefits over regular cooking oils is weak and mixed, and one major DAG oil product was pulled from the market over a processing-related contaminant concern. Talk with your pharmacist or doctor before relying on it for any health purpose.

Edible oil component (derived from vegetable oils such as soybean and rapeseed) · Cooking oil, salad dressings, and processed food products

An interaction check asks whether these two react with each other — it does not ask whether Diacylglycerol is a good idea for someone in your situation. Here is what our Diacylglycerol record says about it on its own.

Diacylglycerol: dosing

There is no established or standardized dose of diacylglycerol for any health benefit. When sold as a cooking oil, it was simply used in place of regular oil in everyday cooking.If you come across a diacylglycerol product, follow the label directions and do not assume that using more will give you any extra benefit.

From our Diacylglycerol monograph — the full record covers uses, side effects and every documented interaction.

Read the full Diacylglycerol monograph & all interactions
Medication

About Cephalexin

What Is Cephalexin Used For?

Brand names: Keflex, Keftab, Cephalex, Lexin

Cephalexin treats bacterial infections caused by susceptible strains of bacteria. It is used for respiratory tract infections, ear infections (otitis media), skin and skin structure infections, bone infections, and genitourinary tract infections — including acute prostatitis.

It works only against bacterial infections — not viruses like colds or flu. Your prescriber should use it only when a bacterial infection is confirmed or strongly suspected, to help prevent antibiotic resistance.

Most-Reported Side Effects for Cephalexin

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Chronic kidney disease 2,157 reports
Renal failure 1,558 reports
Acute kidney injury 1,550 reports
Diarrhea 1,405 reports
Fatigue 1,303 reports
See full Cephalexin drug information
Keep checking

Other Drugs & Diacylglycerol

Browse every other medication we’ve checked against Diacylglycerol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Diacylglycerol References

The 1 sources that drive our Diacylglycerol monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Diacylglycerol is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Fats Explained — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Diacylglycerol and Cephalexin Together: Common Questions

Is it safe to take Diacylglycerol with Cephalexin?
We do not list a known interaction between Diacylglycerol and Cephalexin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Cephalexin interact with any supplements?
Yes. Cephalexin has documented interactions with 61 supplements in our database — Diacylglycerol is not one of them. The Cephalexin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cephalexin and Diacylglycerol?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.