Drug & supplement interaction

Dragon's Blood + Pantoprazole

Pantoprazole brand names: Protonix, Pantoloc, Protonix IV.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Dragon's Blood and Pantoprazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Dragon's Blood and Pantoprazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pantoprazole and Dragon's Blood in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Dragon's Blood at all — not against Pantoprazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dragon's Blood safety at a glance

Dragon's Blood overall Use caution Topical use is generally considered low-risk for most people, but human safety data are limited and product sources vary.
Pregnancy Avoid There is not enough safety information, so it is best to avoid use during pregnancy.
Breastfeeding Avoid Safety has not been established while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pantoprazole and Dragon's Blood? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Pantoprazole’s Own FDA Label Lists

This is not an interaction — none of it involves Dragon's Blood. These are the most notable effects listed in the ADVERSE REACTIONS section of Pantoprazole’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Low magnesium Worth acting on
  • Bone thinning Worth acting on
  • Severe muscle breakdown Worth acting on
  • Low sodium Worth acting on
  • Low potassium Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Confusion Worth acting on
  • A severe skin reaction Worth acting on
  • Low mood Worth acting on

Showing the 10 most notable of 40 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Pantoprazole. Read the label on DailyMed › Dragon's Blood’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Dragon's Blood side to compare — that is a limit of the record, not a statement that Dragon's Blood has no side effects.

From our Q&A

Questions About Dragon's Blood or Pantoprazole

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Dragon's Blood or Pantoprazole, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Pantoprazole

This page covers Dragon's Blood only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pantoprazole page lists 152 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 100 moderate · 49 minor.

From our pharmacist’s overview on the Pantoprazole page

“Pantoprazole (Protonix) is a stomach acid reducer for reflux and ulcers, generally an easy drug to live with, but three of the 152 supplements and herbs on this list earn genuine caution. Grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Pantoprazole interaction page

One more smart check

Taking Dragon's Blood as Part of a Dietary Supplement Product? Check It for Interactions

We hold 21 real supplement products containing Dragon's Blood, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dragon's Blood. Even though Dragon's Blood itself has no known interaction with Pantoprazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dragon's Blood and Pantoprazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dragon's Blood
Steady interest

#1,233 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pantoprazole
Top 25%

#399 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Dragon's Blood is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dragon's Blood reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Dragon's Blood and Pantoprazole records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dragon's Blood

What is Dragon's Blood?

Dragon's Blood
  • Wound healing and skin care
  • Digestive upset and diarrhea
  • Minor cuts and insect bites
  • Sore throat and mouth sores
  • Anti-inflammatory skincare

Dragon's Blood is a red plant resin used in traditional medicine for wound healing, skin problems, and digestive complaints. Some early research on certain types (especially Croton lechleri "Sangre de Drago") is promising for the gut and skin, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially while pregnant or breastfeeding.

Red resin (sap) from the bark, stem, or fruit, depending on the source plant · Resin powder, capsules, tinctures, topical liquids, creams, and skincare products

An interaction check asks whether these two react with each other — it does not ask whether Dragon's Blood is a good idea for someone in your situation. Here is what our Dragon's Blood record says about it on its own.

Dragon's Blood: dosing

There is no established standard dose for Dragon's Blood. The right amount depends on the specific plant source, the product type (resin, tincture, capsule, or cream), and how it is being used.If you choose to use a Dragon's Blood product, follow the directions on the label and do not exceed the suggested amount.

From our Dragon's Blood monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dragon's Blood monograph & all interactions
Medication

About Pantoprazole

What Is Pantoprazole Used For?

Brand names: Protonix, Pantoloc, Protonix IV

Pantoprazole delayed-release tablets and oral suspension are used in adults and children 5 years and older to heal erosive esophagitis (EE) — damage to the esophagus caused by stomach acid — and to relieve GERD symptoms short-term (up to 8 weeks). In adults, they are also used to maintain that healing and reduce heartburn relapse, and to treat conditions where the stomach makes too much acid, including Zollinger-Ellison (ZE) Syndrome.

Intravenous (IV) pantoprazole — given by injection or infusion in a clinical setting — is approved in adults for short-term treatment of GERD with a history of erosive esophagitis (up to 10 days) and for pathological hypersecretory conditions including ZE Syndrome. PROTONIX I.V. is also approved for GERD/EE in pediatric patients 3 months and older (up to 7 days). IV pantoprazole is not approved for treating upper gastrointestinal bleeding.

Most-Reported Side Effects for Pantoprazole

From FAERS, the FDA’s public side-effect reporting system (330,179 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Chronic kidney disease 29,250 reports
Fatigue 24,670 reports
Nausea 22,675 reports
Acute kidney injury 21,404 reports
Diarrhea 21,213 reports
See full Pantoprazole drug information
Keep checking

Other Drugs & Dragon's Blood

Browse every other medication we’ve checked against Dragon's Blood — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Dragon's Blood against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Dragon's Blood list.

See the full Dragon's Blood interactions page
See every supplement checked against Pantoprazole, ranked by severity
Evidence & sources

Dragon's Blood References

The 2 sources that drive our Dragon's Blood monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Dragon's Blood is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dragon's Blood and Pantoprazole Together: Common Questions

Is it safe to take Dragon's Blood with Pantoprazole?
We do not list a known interaction between Dragon's Blood and Pantoprazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Pantoprazole interact with any supplements?
Yes. Pantoprazole has documented interactions with 152 supplements in our database — Dragon's Blood is not one of them. The Pantoprazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Dragon's Blood monograph Uses, safety profile, and every drug interaction in one place Pantoprazole drug information The full plain-English guide to this medication Pantoprazole supplement interactions Every supplement checked against Pantoprazole, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pantoprazole and Dragon's Blood?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.