Drug & supplement interaction

Energy Therapy + Imipramine

Imipramine brand names: Tofranil, Tofranil PM.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Energy Therapy and Imipramine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Energy Therapy and Imipramine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Imipramine and Energy Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Energy Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Energy Therapy at all — not against Imipramine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Energy Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Energy Therapy safety at a glance

Energy Therapy overall Use caution Generally low-risk as a complementary practice, but it should never replace proven medical treatment.
Pregnancy Use caution Gentle, non-invasive sessions are unlikely to harm, but discuss any therapy with your doctor first.
Breastfeeding Use caution No known direct harm, but it is not a treatment and should not replace medical care.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Imipramine and Energy Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Imipramine’s Own FDA Label Lists

This is not an interaction — none of it involves Energy Therapy. These are the most notable effects listed in the ADVERSE REACTIONS section of Imipramine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you have Energy Therapy and take the medicine. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Dependence or withdrawal symptoms Worth acting on
  • A bowel blockage Worth acting on
  • Trouble passing urine Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • A heart attack Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Heart failure Worth acting on

Showing the 10 most notable of 52 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Imipramine. Read the label on DailyMed › Energy Therapy’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Energy Therapy side to compare — that is a limit of the record, not a statement that Energy Therapy has no side effects.

From our Q&A

Questions About Energy Therapy or Imipramine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Energy Therapy or Imipramine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Imipramine

This page covers Energy Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Imipramine page lists 254 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 11 major · 190 moderate · 53 minor.

From our pharmacist’s overview on the Imipramine page

“Imipramine (Tofranil) is an older tricyclic antidepressant, and the supplements on this page deserve real scrutiny before you add one. Most of the list acts on the liver enzymes that process the drug, so an ingredient can quietly raise or lower imipramine levels: grapefruit pushes them up, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Imipramine interaction page

How much people look this up

Where Energy Therapy and Imipramine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Energy Therapy
Steady interest

#1,106 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Imipramine
Top half

#1,165 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Energy Therapy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Energy Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Energy Therapy and Imipramine records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Energy Therapy

What is Energy Therapy?

  • Stress and relaxation
  • Pain relief
  • Anxiety
  • Improved sense of well-being
  • Support during cancer or other illness
  • Better sleep

Energy therapy is a group of mind-body practices (such as Reiki, therapeutic touch, and healing touch) that aim to balance a person's "energy field" to support relaxation and well-being. There is no proven biological energy field, and high-quality evidence for medical benefits is limited, though many people find these sessions calming. It is generally low-risk when used alongside—not instead of—standard medical care.

Not applicable (a practice, not a plant or substance) · Hands-on or hands-near-body sessions, distance sessions, self-treatment techniques

An interaction check asks whether these two react with each other — it does not ask whether Energy Therapy is a good idea for someone in your situation. Here is what our Energy Therapy record says about it on its own.

Energy Therapy: dosing

There is no standardized "dose" for energy therapy. Sessions vary in length (often around 20–60 minutes) and frequency depending on the practitioner and your goals.If you choose to try it, look for a qualified, reputable practitioner, and consider it a complement to—not a substitute for—your medical care.

From our Energy Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Energy Therapy monograph & all interactions
Medication

About Imipramine

What Is Imipramine Used For?

Brand names: Tofranil, Tofranil PM

Imipramine is used to relieve symptoms of depression. Both Imipramine Hydrochloride tablets and Imipramine Pamoate capsules are approved for this use. Endogenous depression — the kind that seems to arise from within rather than a clear outside cause — tends to respond especially well. It may take one to three weeks before you notice the full benefit.

Imipramine Hydrochloride tablets are also approved as a short-term, add-on treatment to help reduce nighttime bedwetting (nocturnal enuresis) in children aged 6 and older, after a doctor has ruled out physical causes.

See full Imipramine drug information
Keep checking

Other Drugs & Energy Therapy

Browse every other medication we’ve checked against Energy Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Energy Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Energy Therapy list.

See the full Energy Therapy interactions page
See every supplement checked against Imipramine, ranked by severity
Evidence & sources

Energy Therapy References

The 2 sources that drive our Energy Therapy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Energy Therapy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Reiki: What You Need To Know — NIH NCCIH Source
  2. Complementary, Alternative, or Integrative Health: What's In a Name? — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Energy Therapy While Taking Imipramine: Common Questions

Is it safe to have Energy Therapy while taking Imipramine?
We do not list a known interaction between Energy Therapy and Imipramine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Imipramine interact with any supplements?
Yes. Imipramine has documented interactions with 254 supplements in our database — Energy Therapy is not one of them. The Imipramine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Energy Therapy monograph Uses, safety profile, and every drug interaction in one place Imipramine drug information The full plain-English guide to this medication Imipramine supplement interactions Every supplement checked against Imipramine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Imipramine and Energy Therapy?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.