Drug & supplement interaction

English Adder's Tongue + Bleomycin

Bleomycin brand name: Blenoxane.

No Known Interaction
The bottom line No known interaction

We found no known interaction between English Adder's Tongue and Bleomycin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

English Adder's Tongue and Bleomycin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Bleomycin and English Adder's Tongue in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for English Adder's Tongue at all — not against Bleomycin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

English Adder's Tongue safety at a glance

English Adder's To... overall Not established Very little modern safety data exists, so caution is warranted, especially when taken by mouth.
Pregnancy Avoid There is no reliable safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Bleomycin and English Adder's Tongue? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Bleomycin’s Own FDA Label Lists

This is not an interaction — none of it involves English Adder's Tongue. These are the most notable effects listed in the ADVERSE REACTIONS section of Bleomycin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Low magnesium Worth acting on
  • A stroke or mini-stroke Worth acting on
  • A heart attack Worth acting on
  • Wheezing Worth acting on
  • Confusion Worth acting on
  • Chest pain Worth acting on
  • Shortness of breath Worth acting on
  • A severe allergic reaction Worth acting on
  • Weight loss
  • Fever mentioned in 12.5% of FDA reports for Bleomycin

Showing the 10 most notable of 20 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Bleomycin. Read the label on DailyMed › Where a percentage is shown, it is the share of 10,271 voluntary FDA FAERS reports for Bleomycin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. English Adder's Tongue’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no English Adder's Tongue side to compare — that is a limit of the record, not a statement that English Adder's Tongue has no side effects.

From our Q&A

Questions About English Adder's Tongue or Bleomycin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers English Adder's Tongue or Bleomycin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Bleomycin

This page covers English Adder's Tongue only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bleomycin page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coffee Charcoal (moderate) and European Mandrake (moderate).

By severity: 1 major · 13 moderate · 9 minor.

Open the Bleomycin interaction page

How much people look this up

Where English Adder's Tongue and Bleomycin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement English Adder's Tongue
Steady interest

#1,426 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Bleomycin
Top 25%

#302 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. English Adder's Tongue is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every English Adder's Tongue reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The English Adder's Tongue and Bleomycin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About English Adder's Tongue

What is English Adder's Tongue?

  • Minor wounds and skin irritation
  • Bruises and swelling
  • Insect bites
  • Soothing inflamed skin
  • Traditional eye washes (historical)

English Adder's Tongue is a small fern long used in folk medicine as a topical remedy for wounds, bruises, and skin irritation. There is very little modern scientific research to show whether it works or how safe it is, so use it cautiously and treat any health claims with skepticism.

Ophioglossum vulgatum · Ophioglossaceae · Leaves (fronds), sometimes the whole plant · Fresh leaves, salve or ointment, poultice, infused oil, tea

An interaction check asks whether these two react with each other — it does not ask whether English Adder's Tongue is a good idea for someone in your situation. Here is what our English Adder's Tongue record says about it on its own.

English Adder's Tongue: dosing

There is no established standardized dose for English Adder's Tongue. Traditional use focused on topical salves and poultices made from the fresh leaves, with no precise measured amounts.If you find a commercial product, follow the directions on the label and do not exceed them.

From our English Adder's Tongue monograph — the full record covers uses, side effects and every documented interaction.

Read the full English Adder's Tongue monograph & all interactions
Medication

About Bleomycin

What Is Bleomycin Used For?

Brand name: Blenoxane

Bleomycin injection is used as a palliative (disease-managing, not curative) treatment for several cancers. It can be used alone or combined with other chemotherapy drugs to treat squamous cell carcinoma of the head and neck (including the mouth, tongue, tonsil, larynx, and other sites), as well as squamous cell carcinomas of the penis, cervix, and vulva. It also treats Hodgkin's disease and non-Hodgkin's lymphoma, and testicular carcinoma (including embryonal cell, choriocarcinoma, and teratocarcinoma subtypes).

When given as an intrapleural injection (directly into the chest cavity), Bleomycin acts as a sclerosing agent — it seals off the space around the lungs to treat malignant pleural effusion and help prevent fluid from coming back.

Most-Reported Side Effects for Bleomycin

From FAERS, the FDA’s public side-effect reporting system (10,271 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Febrile neutropenia 826 reports
Neutropenia 600 reports
Fever 463 reports
Pulmonary toxicity 415 reports
Vomiting 370 reports
See full Bleomycin drug information
Keep checking

Other Drugs & English Adder's Tongue

Browse every other medication we’ve checked against English Adder's Tongue — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

English Adder's Tongue References

The 2 sources that drive our English Adder's Tongue monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. English Adder's Tongue is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking English Adder's Tongue and Bleomycin Together: Common Questions

Is it safe to take English Adder's Tongue with Bleomycin?
We do not list a known interaction between English Adder's Tongue and Bleomycin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Bleomycin interact with any supplements?
Yes. Bleomycin has documented interactions with 23 supplements in our database — English Adder's Tongue is not one of them. The Bleomycin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Bleomycin and English Adder's Tongue?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.