Drug & supplement interaction

Gras + Lemborexant

Lemborexant brand name: Dayvigo.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Gras and Lemborexant in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Gras and Lemborexant

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lemborexant and Gras in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Gras at all — not against Lemborexant, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Gras safety at a glance

Gras overall Not established We cannot confirm what "Gras" is, so its safety is unknown.
Pregnancy Avoid Because the product is unidentified, avoid it during pregnancy unless a doctor confirms it is safe.
Breastfeeding Avoid With no reliable information, avoid it while breastfeeding unless cleared by your doctor.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lemborexant and Gras? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lemborexant’s Own FDA Label Lists

This is not an interaction — none of it involves Gras. These are the most notable effects listed in the ADVERSE REACTIONS section of Lemborexant’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • Thoughts of self-harm Worth acting on mentioned in 10.1% of FDA reports for Lemborexant
  • Hallucinations Worth acting on
  • Low mood Worth acting on
  • Vivid dreams or nightmares
  • Drowsiness mentioned in 5.1% of FDA reports for Lemborexant
  • A fast or pounding heartbeat
  • Trouble sleeping
  • Tiredness
  • Headache mentioned in 3.4% of FDA reports for Lemborexant

From the ADVERSE REACTIONS section of the FDA label for Lemborexant. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,745 voluntary FDA FAERS reports for Lemborexant that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Gras’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Gras side to compare — that is a limit of the record, not a statement that Gras has no side effects.

Everything else you take

See Every Supplement That Interacts With Lemborexant

This page covers Gras only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lemborexant page lists 195 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 9 major · 147 moderate · 39 minor.

From our pharmacist’s overview on the Lemborexant page

“Lemborexant (Dayvigo) works by quieting the brain's wake signals, so the biggest risks on this list come from anything else that sedates you. Alcohol sits at the top; a drink layered over a dose can deepen drowsiness into real impairment, and a few entries carry the added danger of slowed breathing.”

Reviewed by 2 · Jul 18, 2026

Open the Lemborexant interaction page

How much people look this up

Where Gras and Lemborexant Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Gras
Steady interest

#821 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lemborexant
Steady interest

#2,080 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Gras is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Gras reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Gras and Lemborexant records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Gras

What is Gras?

We could not find reliable information about a dietary supplement or herb called "Gras." The name may be a misspelling, a brand name, or a local/regional term, so we cannot confirm what it is, what it does, or whether it is safe. Please double-check the name with your pharmacist or the product label before using it.

An interaction check asks whether these two react with each other — it does not ask whether Gras is a good idea for someone in your situation. Here is what our Gras record says about it on its own.

Gras: dosing

There is no established or recommended dose for "Gras" because the product cannot be reliably identified. We will not guess an amount. If you have a labeled product, follow the manufacturer's instructions only after confirming the actual ingredient with a pharmacist or doctor.

From our Gras monograph — the full record covers uses, side effects and every documented interaction.

Read the full Gras monograph & all interactions
Medication

About Lemborexant

What Is Lemborexant Used For?

Brand name: Dayvigo

Dayvigo (lemborexant) is used to treat insomnia in adults. It helps people who have trouble falling asleep, staying asleep, or both.

It is not approved for use in children. Only the oral tablet form is available under the brand name Dayvigo.

Most-Reported Side Effects for Lemborexant

From FAERS, the FDA’s public side-effect reporting system (2,745 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Suicide attempt 148 reports
Somnolence 140 reports
Suicidal ideation 130 reports
Fall 105 reports
Nausea 95 reports
See full Lemborexant drug information
Keep checking

Other Drugs & Gras

Browse every other medication we’ve checked against Gras — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Gras References

The 3 sources that drive our Gras monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Gras is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary and Herbal Supplements — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
  3. Generally Recognized as Safe (GRAS) — U.S. Food and Drug Administration Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Gras and Lemborexant Together: Common Questions

Is it safe to take Gras with Lemborexant?
We do not list a known interaction between Gras and Lemborexant. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Lemborexant interact with any supplements?
Yes. Lemborexant has documented interactions with 195 supplements in our database — Gras is not one of them. The Lemborexant interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Lemborexant and Gras?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.