Drug & supplement interaction

Kinetin + Dipyridamole

Dipyridamole brand names: Persantine, Dipyridamole, Persantin, Persantin Injection, Persantin Retard.

Moderate Interaction
The bottom line Moderate

Kinetin has a moderate interaction with Dipyridamole. In vitro research suggests that kinetin inhibits human platelet aggregation and activation.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Kinetin and Dipyridamole

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTICOAGULANT/ANTIPLATELET DRUGS

Why this applies to Dipyridamole

Dipyridamole falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Kinetin interacts with.

In vitro research suggests that kinetin inhibits human platelet aggregation and activation. Also, evidence from animal research suggests that kinetin prolongs bleeding time. Theoretically, kinetin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version. Your dipyridamole already works by making platelets less likely to clump together, which is exactly how it lowers your clot risk after a heart valve replacement. In lab and animal studies, kinetin seems to do a similar thing, calming platelets and lengthening bleeding time. Stack the two and, in theory, you could nudge yourself toward easier bruising, nosebleeds, bleeding gums, or cuts that take longer to stop.

The big caveat: this concern comes only from test-tube and animal research, not from real people, so it's more theoretical than proven. Kinetin is also used mainly as a skin cream, which is unlikely to affect your blood. Still, before swallowing any kinetin product, please run it past your pharmacist or doctor first.

References
  1. Hsiao, G., Shen, M. Y., Lin, K. H., Chou, C. Y., Tzu, N. H., Lin, C. H., Chou, D. S., Chen, T. F., and Sheu, J. R. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol PubMed
  2. Sheu, J. R., Hsiao, G., Shen, M. Y., Chou, C. Y., Lin, C. H., Chen, T. F., and Chou, D. S. Inhibitory mechanisms of kinetin, a plant growth-promoting hormone, in platelet aggregation. Platelets. 2003;14(3):189-196. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Kinetin Also Interacts With Other Medications

Kinetin has 121 moderate known drug interactions in our database — the Dipyridamole one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Kinetin

Covers the 2,830 medications we’ve checked against Kinetin. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Dipyridamole

This page covers Kinetin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dipyridamole page lists 219 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Adenosine (major), Danshen (major), Piracetam (major) and Aconite (moderate).

By severity: 4 major · 190 moderate · 25 minor.

From our pharmacist’s overview on the Dipyridamole page

“Dipyridamole (Persantine) keeps platelets from clumping so clots don't form, often after a stroke or heart valve surgery, and that job is exactly why the 219 supplements on this page warrant real vigilance. The bulk of the list, including most of the 190 moderate entries, adds its own blood-thinning or antiplatelet effect on top of the…”

Reviewed by 2 · Jul 18, 2026

Open the Dipyridamole interaction page

How much people look this up

Where Kinetin and Dipyridamole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Kinetin
Steady interest

#1,386 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dipyridamole
Top 25%

#590 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Kinetin

What is Kinetin?

  • Anti-aging skincare
  • Skin smoothing and texture
  • Reducing skin dryness and roughness
  • Evening skin tone
  • Cosmetic moisturizing

Kinetin is a plant growth hormone (a cytokinin) used mainly in topical anti-aging and skincare products, not as an oral dietary supplement. Early laboratory research and small studies suggest it may help skin texture and hydration, but high-quality human evidence is limited. If you want to try it, use it as a cosmetic skin product and check with a pharmacist or dermatologist, especially if you have sensitive skin.

Read the full Kinetin monograph & all interactions
Medication

About Dipyridamole

What Is Dipyridamole Used For?

Brand names: Persantine, Dipyridamole, Persantin, Persantin Injection, Persantin Retard

Dipyridamole tablets are used alongside warfarin (a blood thinner) to help prevent dangerous blood clots from forming after cardiac valve replacement surgery. It is not used alone for this purpose — it works as an add-on to anticoagulant therapy.

Dipyridamole Injection is used as an alternative to exercise during thallium myocardial perfusion imaging — a type of heart scan that checks blood flow through the coronary arteries. It is given to patients who are unable to exercise adequately for the test.

See full Dipyridamole drug information
Keep checking

Other Drugs & Kinetin

Browse every other medication we’ve checked against Kinetin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
121Moderate
0Minor
2,708No known interaction
Moderate

121 interactions

Showing 60 of 121 moderate interactions — see all 121 on the Kinetin page.

No interaction 2,708 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Kinetin and Dipyridamole Together: Common Questions

Can you take Kinetin with Dipyridamole?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Kinetin and Dipyridamole interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.