Medication interaction hub

What Supplements Interact with Dipyridamole?

Dipyridamole brand names: Persantine, Dipyridamole, Persantin, Persantin Injection, Persantin Retard. Every interaction below applies to the brands too.

219 Interactions 4 Major 190 Moderate 25 Minor

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Dipyridamole (Persantine) keeps platelets from clumping so clots don't form, often after a stroke or heart valve surgery, and that job is exactly why the 219 supplements on this page warrant real vigilance. The bulk of the list, including most of the 190 moderate entries, adds its own blood-thinning or antiplatelet effect on top of the drug's, stacking the bleeding risk. Four rate major, and danshen sits there for that very reason.

Two other patterns are easy to miss. Caffeine, coffee and tea included, can blunt the blood-vessel-widening effect dipyridamole relies on and should be stopped 24 hours before a dipyridamole stress test. Activated charcoal, another of the four majors, can soak up the drug before it reaches your blood, so keep it and bulky fiber supplements well apart from your dose. The 25 minor entries carry lower stakes, but read the majors first.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Dipyridamole: Top Interactions at a Glance

The Dipyridamole supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 219 interacting ingredients — plus 1,233 more checked with no known interaction. See the complete ranked list.

The complete list

Every Supplement Checked Against Dipyridamole

All 1,452 ingredients in our database, ranked by severity — 219 with a Dipyridamole interaction on file and 1,233 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Straight answers

Can You Take It With Dipyridamole?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Adenosine with Dipyridamole?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Dipyridamole can increase the therapeutic and toxic effects of adenosine.

Full Adenosine + Dipyridamole answer

Can you take Goldenseal with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goldenseal might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Goldenseal + Dipyridamole answer

Can you take Melatonin with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, melatonin may have anticoagulant effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet dru...

Full Melatonin + Dipyridamole answer

Can you take Clove with Dipyridamole?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, clove oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Clove + Dipyridamole answer

Can you take Asafoetida with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, asafoetida might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.

Full Asafoetida + Dipyridamole answer

Can you take Rose Hip with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.

Full Rose Hip + Dipyridamole answer

Can you take Rosemary with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Rosemary + Dipyridamole answer

Can you take Safflower with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Safflower + Dipyridamole answer

Can you take Saw Palmetto with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.

Full Saw Palmetto + Dipyridamole answer

Can you take Sea Buckthorn with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Sea Buckthorn + Dipyridamole answer

Can you take Selenium with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Selenium + Dipyridamole answer

Can you take Serrapeptase with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleedi...

Full Serrapeptase + Dipyridamole answer

Can you take Slippery Elm with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Dipyridamole answer

Can you take Sorrel with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.

Full Sorrel + Dipyridamole answer

Can you take Strawberry with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro and animal research suggests that strawberry extract can inhibit platelet aggregation due to its phenolic content.

Full Strawberry + Dipyridamole answer

Can you take Summer Savory with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that summer savory extract inhibits platelet aggregation and adhesion.

Full Summer Savory + Dipyridamole answer

Can you take Swallowroot with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, swallowroot might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Swallowroot + Dipyridamole answer

Can you take Sweet Clover with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fresh sweet clover might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Sweet Clover + Dipyridamole answer

Can you take Sweet Vernal Grass with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hay prepared from dried sweet vernal grass contains an anticoagulant, dicoumarol, which has been associated with fatal hemorrhages in animal...

Full Sweet Vernal Grass + Dipyridamole answer

Can you take Tarragon with Dipyridamole?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that tarragon extract inhibits platelet aggregation and adhesion.

Full Tarragon + Dipyridamole answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Dipyridamole is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Dipyridamole, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Dipyridamole sits in 3 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Dipyridamole through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Dipyridamole through this category.

Dipyridamole (Persantine) 13 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

13 of the supplement ingredients on this page reach Dipyridamole through this category.

About Dipyridamole

Dipyridamole is a platelet-inhibiting medication used to help prevent blood clots after cardiac valve replacement surgery and, as an injection, to assist in heart imaging tests.

Generic name: Dipyridamole  ·  Brand names: Persantine, Dipyridamole, Persantin, Persantin Injection, Persantin Retard.

See the full Dipyridamole drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Dipyridamole

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Dipyridamole.

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Pharmacist Counseling Corner

Dipyridamole & Supplements: Common Questions

What supplements interact with Dipyridamole?
Our database currently documents 219 ingredients with a known Dipyridamole interaction (4 major, 190 moderate, 25 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 219. The highest-ranked right now: Adenosine, Activated Charcoal, Danshen.
Which Dipyridamole supplement interactions are the most serious?
Focus on the major group: Adenosine, Activated Charcoal, Danshen and Piracetam. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Dipyridamole?
Plenty of supplements coexist fine with Dipyridamole; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Persantine have the same supplement interactions as Dipyridamole?
Yes — Persantine, Dipyridamole, Persantin, Persantin Injection, Persantin Retard all contain Dipyridamole, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Dipyridamole and my other medications?
This page covers Dipyridamole against supplements and herbal ingredients. Checking Dipyridamole against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Dipyridamole drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 25, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.