Drug & supplement interaction

Kinetin + Frovatriptan

Frovatriptan brand name: Frova.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Kinetin and Frovatriptan in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Kinetin and Frovatriptan

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Frovatriptan and Kinetin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Kinetin safety at a glance

Kinetin overall Use caution Generally used topically in cosmetics; oral supplement use is not well studied and not recommended.
Pregnancy Avoid There is not enough safety information, so it is best to avoid during pregnancy unless your doctor approves.
Breastfeeding Avoid Safety during breastfeeding has not been established, so caution or avoidance is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Frovatriptan and Kinetin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Frovatriptan

Interactions in our licensed database are recorded against drug classes, not just single drug names. Frovatriptan is filed under 3 classifications — serotonergic drugs, serotonergic drugs, oral drugs. Kinetin has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Frovatriptan’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Kinetin Does Interact With Other Medications

Kinetin has 122 moderate known drug interactions in our database — Frovatriptan isn’t one of them. If you take anything else, check it against the full list below.

Moderate 122 No known interaction 2,708 (incl. Frovatriptan)
Taking anything else?

Check Another of Your Medications Against Kinetin

Covers the 2,830 medications we’ve checked against Kinetin. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Kinetin and Frovatriptan May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Ringing in the ears Additional detail

    Kinetin

    “Orally, the most common adverse effect reported from kinetin is nausea. Headache, diarrhea, tinnitus, flushing, and rash are less common. Topically, kinetin seems to be well tolerated. Erythema, dryness, peeling, burning, stinging, and itching have been reported. However, it is unknown if these symptoms are related to kinetin or other ingredients in the products used.”

    Kinetin · Natural Medicines adverse-effect record, reported in cluster headache.

    3 sources cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
    2. 100044. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed
    3. 100050. Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clin Exp Dermatol. 2007;32(6):693-5. PubMed

    “Orally, kinetin has been reported to cause tinnitus rarely. Limited research suggests that this reaction is not dose-dependent.”

    Kinetin · Natural Medicines adverse-effect record, reported in tinnitus.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Frovatriptan

    Listed in the ADVERSE REACTIONS section of the FDA label for Frovatriptan. Read the label on DailyMed ›

  • Flushing Additional detail

    Kinetin

    “Orally, kinetin has been reported to cause flushing and rash rarely. Limited research suggests that these reactions are not dose-dependent. Topically, kinetin has been reported to cause erythema, dryness, peeling, burning, stinging, and itching. However, it is unknown if these symptoms are related to kinetin or other ingredients in the products used.”

    Kinetin · Natural Medicines adverse-effect record, reported in erythema.

    2 sources cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
    2. 100044. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed

    Frovatriptan

    Listed in the ADVERSE REACTIONS section of the FDA label for Frovatriptan. Read the label on DailyMed ›

  • Diarrhea Additional detail

    Kinetin

    “Orally, the most common adverse effect reported from kinetin is nausea. Lower doses generally cause mild nausea; however, doses of 16.8 mg/kg to 23.5 mg/kg daily increase the chance of severe nausea. Kinetin has also been reported to cause diarrhea, although at a lower rate.”

    Kinetin · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Frovatriptan

    Listed in the ADVERSE REACTIONS section of the FDA label for Frovatriptan. Read the label on DailyMed ›

  • Headache Additional detail

    Kinetin

    “Orally, kinetin has been reported to cause headache rarely. Limited research suggests that this reaction is not dose-dependent.”

    Kinetin · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Frovatriptan

    Listed in the ADVERSE REACTIONS section of the FDA label for Frovatriptan. Read the label on DailyMed ›

Reported for Kinetin but not commonly for Frovatriptan: itching, nausea and a skin rash.

Effects for Frovatriptan come from the ADVERSE REACTIONS section of its FDA label; effects for Kinetin come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Kinetin or Frovatriptan

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Kinetin or Frovatriptan, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Frovatriptan

This page covers Kinetin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Frovatriptan page lists 38 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Lithium (major), 5-htp (moderate), Acetyl-l-carnitine (moderate) and Ayahuasca (moderate).

By severity: 2 major · 25 moderate · 11 minor.

From our pharmacist’s overview on the Frovatriptan page

“If you take frovatriptan (Frova) for migraine attacks, lithium is the interaction to understand first. Frovatriptan itself works through serotonin, and lithium, one of two major-rated entries among the 38 supplements on file, can both mask and raise the risk of serotonin syndrome.”

Reviewed by 2 · Jul 18, 2026

Open the Frovatriptan interaction page

How much people look this up

Where Kinetin and Frovatriptan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Kinetin
Steady interest

#861 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Frovatriptan
Steady interest

#2,539 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Kinetin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Kinetin and Frovatriptan records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Kinetin

What is Kinetin?

  • Anti-aging skincare
  • Skin smoothing and texture
  • Reducing skin dryness and roughness
  • Evening skin tone
  • Cosmetic moisturizing

Kinetin is a plant growth hormone (a cytokinin) used mainly in topical anti-aging and skincare products, not as an oral dietary supplement. Early laboratory research and small studies suggest it may help skin texture and hydration, but high-quality human evidence is limited. If you want to try it, use it as a cosmetic skin product and check with a pharmacist or dermatologist, especially if you have sensitive skin.

Plant-derived cytokinin (a type of plant hormone); used as a purified compound · Topical creams, serums, lotions, and cosmetic skincare products

An interaction check asks whether these two react with each other — it does not ask whether Kinetin is a good idea for someone in your situation. Here is what our Kinetin record says about it on its own.

Kinetin: dosing

There is no established standard dose for kinetin, and it is not meant to be taken as an oral supplement. In cosmetic skincare, it appears as one ingredient among many, usually in low concentrations.The best approach is to follow the directions on the product label for how often to apply it. Do not assume that using more product more often will give better results.

From our Kinetin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Kinetin monograph & all interactions
Medication

About Frovatriptan

What Is Frovatriptan Used For?

Brand name: Frova

Frovatriptan succinate tablets are used to treat a migraine headache once it has already started — with or without aura (visual or sensory symptoms that can precede a migraine). It is approved for adults only.

It is not used to prevent migraines from happening in the first place, and it has not been proven effective for cluster headaches. A clear diagnosis of migraine should be established before use.

See full Frovatriptan drug information
Keep checking

Other Drugs & Kinetin

Browse every other medication we’ve checked against Kinetin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
0Minor
2,707No known interaction
122 Moderate 2,707 No interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Kinetin page.

No interaction 2,707 drugs checked — show the list

We also checked Kinetin against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,707 medications checked with no known interaction — see the full Kinetin list.

See the full Kinetin interactions page
See every supplement checked against Frovatriptan, ranked by severity
Evidence & sources

Kinetin References

The 7 references that drive our Kinetin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hsiao, G., Shen, M. Y., Lin, K. H., Chou, C. Y., Tzu, N. H., Lin, C. H., Chou, D. S., Chen, T. F., and Sheu, J. R. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol PubMed
  2. Adunka, O., Moustaklis, E., Weber, A., May, A., von Ilberg, C., Gstoettner, W., and Kierner, A. C. Labyrinth anesthesia--a forgotten but practical treatment option in Meniere's disease. ORL J Otorhinolaryngol.Relat Spec. 2003;65(2):84-90.
  3. Sheu, J. R., Hsiao, G., Shen, M. Y., Chou, C. Y., Lin, C. H., Chen, T. F., and Chou, D. S. Inhibitory mechanisms of kinetin, a plant growth-promoting hormone, in platelet aggregation. Platelets. 2003;14(3):189-196. PubMed
  4. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed
  5. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
  6. Chiu PC, Chan CC, Lin HM, Chiu HC. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. J Cosmet Dermatol. 2007;6(4):243-9. PubMed
  7. Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clin Exp Dermatol. 2007;32(6):693-5. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Kinetin and Frovatriptan Together: Common Questions

Is it safe to take Kinetin with Frovatriptan?
We do not list a known interaction between Kinetin and Frovatriptan. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Kinetin and Frovatriptan have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Kinetin and Frovatriptan combination checked?
Interactions in our licensed database are recorded against drug classes. Frovatriptan is filed under 3 classifications, and Kinetin has documented interactions with 1 drug class — none of Frovatriptan's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Kinetin interact with any other medications?
Yes. Kinetin has 122 documented drug interactions in our database — Frovatriptan is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Frovatriptan interact with any supplements?
Yes. Frovatriptan has documented interactions with 38 supplements in our database — Kinetin is not one of them. The Frovatriptan interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Kinetin monograph Uses, safety profile, and every drug interaction in one place Frovatriptan drug information The full plain-English guide to this medication Frovatriptan supplement interactions Every supplement checked against Frovatriptan, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 7 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Frovatriptan and Kinetin?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.