Drug & supplement interaction

Krill Oil + Finerenone

Finerenone brand name: Kerendia.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Krill Oil and Finerenone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Krill Oil and Finerenone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Finerenone and Krill Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Krill Oil safety at a glance

Krill Oil overall Use caution Generally well tolerated, but avoid if you have a shellfish allergy and use caution if you have a bleeding disorder.
Pregnancy Use caution Not enough reliable safety data; talk to your doctor before using during pregnancy.
Breastfeeding Use caution Not enough reliable safety data; talk to your doctor before using while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Finerenone and Krill Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Finerenone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Finerenone is filed under 3 classifications — potassium-sparing diuretics, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Krill Oil has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and antidiabetes drugs (moderate) — and none of Finerenone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Krill Oil Does Interact With Other Medications

Krill Oil has 208 moderate known drug interactions in our database — Finerenone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 208 No known interaction 2,622 (incl. Finerenone)
Taking anything else?

Check Another of Your Medications Against Krill Oil

Covers the 2,830 medications we’ve checked against Krill Oil. Pick one to open its full report.

What to actually watch for

What Krill Oil Itself Has Been Linked To

This is not an interaction — nothing below involves Finerenone. It is the side-effect record for Krill Oil on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Krill Oil, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Raised blood pressure Worth acting on Additional detail

    “Orally, krill oil may cause hypertension, but this effect has only been observed for one patient in one clinical trial.”

    Krill Oil · Natural Medicines adverse-effect record, reported in hypertension.

    1 source cited
    1. 91600. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  • Heartburn / Bloating or gas / Reduced appetite / Stomach upset / Diarrhea Additional detail

    “Orally, krill oil may cause gastrointestinal side effects including stomach discomfort or upset, decreased appetite, taste change, heartburn, fishy burps, bloating, flatulence, diarrhea, vomiting, and nausea. However, these effects seem to be less severe or occur less often with krill oil compared to fish oil.”

    Krill Oil · Natural Medicines adverse-effect record, reported in diarrhea.

    6 sources cited
    1. 57836. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
    2. 91599. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
    3. 91600. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
    4. 110372. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
    5. 110374. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed
    6. 15754. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  • Sore throat Additional detail

    “When taken orally, sore throat has been reported rarely in clinical research.”

    Krill Oil · Natural Medicines adverse-effect record, reported in pharyngitis.

    2 sources cited
    1. 110372. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
    2. 110374. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed
  • Tiredness / Dizziness Additional detail

    “When taken orally, headache, tiredness, and dizziness have been reported rarely in clinical research.”

    Krill Oil · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 110372. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
    2. 110374. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed
  • Vomiting Additional detail

    Recorded for Krill Oil in the same Natural Medicines adverse-effect record shown under Heartburn / Bloating or gas / Reduced appetite / Stomach upset / Diarrhea above.

Showing the 10 most notable of 12 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Krill Oil — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Finerenone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Finerenone column appears here.

Overlapping uses

What Finerenone Is Prescribed For, and What Krill Oil Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Finerenone is a prescription medicine with approved uses on its FDA label. Krill Oil is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Finerenone is prescribed for: Kerendia (finerenone) is used in adults with chronic kidney disease (CKD) linked to type 2 diabetes. It helps reduce the risk of kidney function decline, end-stage kidney disease, cardiovascular death, non-fatal heart attack, and hospitalization for heart failure in these patients. Kerendia is also used in adults with heart failure who have a left ventricular ejection fraction (LVEF) — a measure of how well the heart pumps — of 40% or higher. In this group, it reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits.

Krill Oil has been studied for:

  • Diabetes studied, not established Krill Oil has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Krill Oil for diabetes

    It is unclear if oral krill oil is beneficial for glycemic control.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Finerenone on your own; if you are taking Krill Oil for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Krill Oil or Finerenone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Krill Oil or Finerenone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Finerenone

This page covers Krill Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Finerenone page lists 146 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 101 moderate · 42 minor.

From our pharmacist’s overview on the Finerenone page

“Kerendia (finerenone) protects the kidneys and heart in people with type 2 diabetes and chronic kidney disease, and because the body clears it through one main enzyme, CYP3A4, its supplement list calls for genuine care. Of the 146 ingredients on file, 121 can push that enzyme up or down, letting finerenone drift too high or too low.”

Reviewed by 2 · Jul 18, 2026

Open the Finerenone interaction page

One more smart check

Taking Krill Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 605 real supplement products containing Krill Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Krill Oil. Even though Krill Oil itself has no known interaction with Finerenone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Krill Oil and Finerenone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Krill Oil
Top 25%

#300 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Finerenone
Steady interest

#2,437 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Krill Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Krill Oil and Finerenone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Krill Oil

What is Krill Oil?

Krill Oil
  • Heart and cholesterol support
  • High triglycerides
  • Joint pain and inflammation
  • Brain and eye health
  • PMS symptoms
  • General omega-3 supplementation

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but the evidence for many other uses is limited. It is generally well tolerated, but people with shellfish allergy should avoid it, and anyone pregnant, breastfeeding, or on blood thinners should check with a pharmacist or doctor first.

Euphausia superba · Euphausiidae · Oil extracted from the whole krill · Softgel capsules, liquid

An interaction check asks whether these two react with each other — it does not ask whether Krill Oil is a good idea for someone in your situation. Here is what our Krill Oil record says about it on its own.

Krill Oil: dosing

There is no single official or standardized dose of krill oil. Products vary in how much EPA and DHA they provide per capsule, so two products may not be equal even at the same number of capsules.The best approach is to follow the directions on the product label and to choose a reputable brand.

From our Krill Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Krill Oil monograph & all interactions
Medication

About Finerenone

What Is Finerenone Used For?

Brand name: Kerendia

Kerendia (finerenone) is used in adults with chronic kidney disease (CKD) linked to type 2 diabetes. It helps reduce the risk of kidney function decline, end-stage kidney disease, cardiovascular death, non-fatal heart attack, and hospitalization for heart failure in these patients.

Kerendia is also used in adults with heart failure who have a left ventricular ejection fraction (LVEF) — a measure of how well the heart pumps — of 40% or higher. In this group, it reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits.

Most-Reported Side Effects for Finerenone

From FAERS, the FDA’s public side-effect reporting system (2,960 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Glomerular filtration rate decreased 308 reports
Hyperkalaemia 261 reports
Blood creatinine increased 226 reports
Blood potassium increased 180 reports
Renal impairment 140 reports
See full Finerenone drug information
Keep checking

Other Drugs & Krill Oil

Browse every other medication we’ve checked against Krill Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
208Moderate
0Minor
2,621No known interaction
208 Moderate 2,621 No interaction
Moderate

208 interactions

Showing 60 of 208 moderate interactions — see all 208 on the Krill Oil page.

No interaction 2,621 drugs checked — show the list

We also checked Krill Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,621 medications checked with no known interaction — see the full Krill Oil list.

See the full Krill Oil interactions page
See every supplement checked against Finerenone, ranked by severity
Evidence & sources

Krill Oil References

The 13 references that drive our Krill Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Krill Oil and Finerenone Together: Common Questions

Is it safe to take Krill Oil with Finerenone?
We do not list a known interaction between Krill Oil and Finerenone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Krill Oil and Finerenone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Krill Oil in each. That is a conversation for your prescriber, especially if Finerenone is being adjusted to a target.
How was the Krill Oil and Finerenone combination checked?
Interactions in our licensed database are recorded against drug classes. Finerenone is filed under 3 classifications, and Krill Oil has documented interactions with 2 drug classes — none of Finerenone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Krill Oil interact with any other medications?
Yes. Krill Oil has 208 documented drug interactions in our database — Finerenone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Finerenone interact with any supplements?
Yes. Finerenone has documented interactions with 146 supplements in our database — Krill Oil is not one of them. The Finerenone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Krill Oil monograph Uses, safety profile, and every drug interaction in one place Finerenone drug information The full plain-English guide to this medication Finerenone supplement interactions Every supplement checked against Finerenone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 13 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Finerenone and Krill Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.