Herb & supplement monograph

Trichopus Zeylanicus Drug Interactions, Uses, Effectiveness, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines

Trichopus Zeylanicus Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Trichopus Zeylanicus drug interaction appears low for most people. None of the listed interactions are rated major, and the entire profile rests on a single theoretical concern that has only been studied in animals.

Interactions deserving the most attention

The one group who should pay attention is people taking immunosuppressants, such as medicines used after an organ transplant or for autoimmune conditions. Animal research suggests Trichopus zeylanicus may stimulate the immune system, which could in theory work against drugs meant to calm it down. Because these medicines depend on keeping the immune system reliably suppressed, even an unproven effect deserves caution in this group.

What the rest of the list means

Although a long list of medications is flagged, they all trace back to this one immune-related concern rather than many separate problems. The evidence comes from animal studies, not human trials, so the effect is theoretical and has not been confirmed to cause meaningful changes in people. For those not taking immune-suppressing medicines, the data does not point to any documented interaction.

Check your medications against Trichopus Zeylanicus

Based on HelloPharmacist’s Trichopus Zeylanicus interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Trichopus Zeylanicus

121 medications have a known interaction with Trichopus Zeylanicus, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
6-mercaptopurinePurinethol› AbrocitinibCibinqo› AdalimumabHumira› Adalimumab-adazHyrimoz› Adalimumab-adbmCyltezo› Adalimumab-afzbAbrilada› Adalimumab-attoAmjevita› Adalimumab-bwwdHadlima› Adalimumab-fkjpHulio› AlefaceptAmevive› AlemtuzumabCampath› Anifrolumab-fniaSaphnelo› Antithymocyte GlobulinThymoglobulin› AtezolizumabTecentriq› AzamuneImmunoprin› AzathioprineAzamune, Imuran› BasiliximabSimulect› Beclometasone DipropionateBecotide› BeclomethasoneBeclovent, Vanceril› Beclomethasone DipropionateQNASL, Qvar› BetamethasoneCelestone, Diprolene AF, Diprosone› Betamethasone DipropionateSernivo› Betamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora› Betamethasone ValerateLuxiq› Bimekizumab-bkzxBimzelx› CiclesonideAlvesco, Omnaris, Zetonna› CisplatinPlatinol-AQ› CladribineLeustatin, Mavenclad› CopanlisibAliqopa› Cortisone AcetateCortisone Tablets, Cortone›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Trichopus Zeylanicus combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Trichopus Zeylanicus affects

Every type of medication (drug category) Trichopus Zeylanicus is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 1 drug category Trichopus Zeylanicus interacts with
Immunosuppressants
Immunosuppressants

Theoretically, Trichopus zeylanicus might reduce the effects of immunosuppressants. Animal research suggests that Trichopus zeylanicus might have immunostimulant effects.

Likelihood Possible Evidence D
Monograph

Trichopus Zeylanicus: Uses, Safety & Side Effects

The bottom line

Trichopus zeylanicus is a tropical herb traditionally used as a tonic to boost energy and resist stress, but human evidence is very limited and mostly based on animal or laboratory studies. Because little is known about its safety, talk with a pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding.

Scientific name
Trichopus zeylanicus
Family
Dioscoreaceae
Part used
Leaves (and sometimes whole plant)
Common forms
Capsules, powder, extracts, teas
People commonly use it for
  • Fatigue and energy
  • Physical stamina
  • Stress and adaptation
  • General tonic/well-being
  • Immune support

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLimited data

Human safety data are very limited, so use cautiously and under professional guidance.

PregnancyBest avoided

Safety has not been established, so avoid use during pregnancy.

BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Trichopus zeylanicus is a small herb that grows in tropical regions, including parts of India and Sri Lanka. In India it is closely linked to a plant the Kani tribal people of the Western Ghats traditionally chewed for stamina, sometimes called "arogyapacha."

The leaves and whole plant have long been used in folk traditions as a tonic to fight tiredness and improve the body's ability to handle stress. Today it is sometimes sold as capsules, powders, or extracts marketed for energy and overall well-being.

How it works

The plant contains natural compounds such as flavonoids, glycolipids, and other plant chemicals that may have antioxidant activity. Researchers have suggested it may act as an adaptogen — a substance thought to help the body resist physical and mental stress.

It is important to know that these proposed mechanisms are based mostly on test-tube and animal experiments. How (or whether) these effects translate to people is not well understood.

Effectiveness

Does Trichopus Zeylanicus work?

Evidence overview · 3 uses evaluated
3 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Trichopus Zeylanicus, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 3 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral Trichopus zeylanicus for weight loss, there is insufficient reliable information about the clinical effects of Trichopus zeylanicus for this purpose.

Insufficient Reliable Evidence To Rate Peptic ulcers
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral Trichopus zeylanicus for peptic ulcers, there is insufficient reliable information about the clinical effects of Trichopus zeylanicus for this purpose.

Insufficient Reliable Evidence To Rate Sexual dysfunction
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral Trichopus zeylanicus for sexual dysfunction, there is insufficient reliable information about the clinical effects of Trichopus zeylanicus for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

There is not enough reliable information about how safe Trichopus zeylanicus is when taken by humans, especially over the long term. Because of this, it should be used cautiously and ideally under the guidance of a healthcare professional.

People who are pregnant or breastfeeding should avoid it, since its safety has not been studied in these groups. Children, older adults, and people with chronic health conditions or those taking prescription medicines should check with a pharmacist or doctor first. Quality and purity of supplements can also vary widely between brands.

Side effects

The side effects of Trichopus zeylanicus in humans are not well documented because formal studies are lacking. As with many herbal products, possible reactions could include stomach upset, nausea, or allergic reactions in sensitive people.

If you notice a rash, swelling, trouble breathing, or any other concerning symptoms after taking it, stop using it and seek medical care promptly.

Dosing

There is no established standard dose for Trichopus zeylanicus. Because reliable human studies are lacking, no safe and effective amount has been confirmed.

If you choose to use a product, follow the directions on the label and do not exceed the recommended amount. It is best to check with a pharmacist or doctor before starting, especially if you take other medicines or have a health condition.

Pregnancy & Breastfeeding

Trichopus Zeylanicus & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Trichopus Zeylanicus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Singh B, Chandan BK, Sharma N, et al. Adaptogenic activity of glyco-peptido-lipid fraction from the alcoholic extract of Trichopus zeylanicus Gaerten (part II). Phytomedicine 2005;12:468-81. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Trichopus Zeylanicus

2 brands in our database make a supplement containing Trichopus Zeylanicus.

Pharmacist Counseling Corner

Trichopus Zeylanicus: Common Questions

What is Trichopus Zeylanicus used for, and does it work?
People use Trichopus Zeylanicus for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Trichopus Zeylanicus interact with prescription medications?
Yes. We list 121 medications with a known interaction with Trichopus Zeylanicus. Use the checker above to see how Trichopus Zeylanicus interacts with a specific drug.
How are Trichopus Zeylanicus interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Trichopus Zeylanicus with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Trichopus Zeylanicus interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Trichopus Zeylanicus used for?
It is traditionally used as a tonic to fight tiredness, boost stamina, and help the body handle stress. These uses are based mostly on folk tradition, not strong scientific proof.
Does Trichopus Zeylanicus really boost energy?
Some animal and lab studies suggest possible energy or anti-fatigue effects, but there is very little human research to confirm this. The evidence is currently too limited to say it works.
Is Trichopus Zeylanicus safe to take?
Its safety in humans has not been well studied. Use it cautiously and talk with a pharmacist or doctor first, especially if you have a health condition or take other medicines.
Can I take it while pregnant or breastfeeding?
No reliable safety data exist for these situations, so it is best to avoid Trichopus Zeylanicus during pregnancy and breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Trichopus Zeylanicus

A rotating sample of real supplements in our database that list Trichopus Zeylanicus — open any to see its full ingredients and every drug interaction we check.

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