Drug & supplement interaction

Lactiplantibacillus Plantarum + Brompheniramine

Brompheniramine brand names: Lodrane, Dimetane.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Lactiplantibacillus Plantarum and Brompheniramine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lactiplantibacillus Plantarum and Brompheniramine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Brompheniramine and Lactiplantibacillus Plantarum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactiplantibacillus Plantarum safety at a glance

Lactiplantibacillu... overall Use caution Generally well tolerated in healthy people, but people with weak immune systems or serious illness should be cautious.
Pregnancy Possibly Safe When used orally and appropriately. Lactiplantibacillus plantarum (Lp299v, DSM 9843) has been used with apparent safety in doses of 10 billion colony-forming un... Read the full pregnancy detail
Breastfeeding Use caution Limited safety data exist, so use only with guidance from your healthcare provider.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Brompheniramine and Lactiplantibacillus Plantarum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Brompheniramine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Brompheniramine is filed under 3 classifications — photosensitizing drugs, seizure threshold lowering drugs, oral drugs. Lactiplantibacillus Plantarum has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Brompheniramine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactiplantibacillus Plantarum Does Interact With Other Medications

Lactiplantibacillus Plantarum has 182 moderate known drug interactions in our database — Brompheniramine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. Brompheniramine)
Taking anything else?

Check Another of Your Medications Against Lactiplantibacillus Plantarum

Covers the 2,830 medications we’ve checked against Lactiplantibacillus Plantarum. Pick one to open its full report.

What to actually watch for

What Lactiplantibacillus Plantarum Itself Has Been Linked To

This is not an interaction — nothing below involves Brompheniramine. It is the side-effect record for Lactiplantibacillus Plantarum on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactiplantibacillus Plantarum, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Lactiplantibacillus plantarum preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Lactobacilli species, including L. plantarum, have been isolated in some cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis. Most cases of L.”

    Lactiplantibacillus Plantarum · Natural Medicines adverse-effect record, reported in cancer.

    3 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 107551. Matsuura H, Kiura Y, Ito T, et al. Lactobacillus bacteremia: a diagnostic clue of rectal cancer. QJM. 2021;114(2):122-123. PubMed
    3. 96890. Topcuoglu S, Gursoy T, Ovali F, Serce O, Karatekin G. A new risk factor for neonatal vancomycin-resistant Enterococcus colonisation: bacterial probiotics. J Matern Fetal Neonatal Med. 2015;28(12):1491-4. PubMed
  • Bloating or gas / Stomach pain / Diarrhea / Nausea Additional detail

    “Orally, taking Lactiplantibacillus plantarum may cause gastrointestinal side effects including diarrhea, loose stools, nausea, stomach pain, rumbling, bloating, and flatulence; however, these events are uncommon.”

    Lactiplantibacillus Plantarum · Natural Medicines adverse-effect record, reported in diarrhea.

    6 sources cited
    1. 90271. Krag A, Munkholm P, Israelsen H, von Ryberg B, Andersen KK, Bendtsen F. Profermin is efficacious in patients with active ulcerative colitis--a randomized controlled trial. Inflamm Bowel Dis. 2013;19(12):2584-92. PubMed
    2. 107497. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
    3. 107556. Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N. Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, doub
    4. 107557. Busch R, Gruenwald J, Dudek S. Randomized, double blind and placebo controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold. Food Nutr Sci 2013;4(11A):13-2. DOI
    5. 112064. Canaviri-Paz P, Oscarsson E, Kjellström A, Olsson H, Jois C, Håkansson Å. Effects on Microbiota Composition after Consumption of Quinoa Beverage Fermented by a Novel Xylose-Metabolizing L. plantarum Strain. Nutrients 2021;13(10):3318. PubMed
    6. 111993. Bengtsson J, Adlerberth I, Östblom A, Saksena P, Öresland T, Börjesson L. Effect of probiotics (Lactobacillus plantarum 299 plus Bifidobacterium Cure21) in patients with poor ileal pouch function: a randomised controlled trial. Scand J Gastroenterol 2016;
  • Dizziness Additional detail

    “Orally, use of Lactiplantibacillus plantarum 299v 10 billion colony-forming units daily has been associated with one case of transient vertigo in one clinical trial.”

    Lactiplantibacillus Plantarum · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 90249. Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol 2012;18(30):4012-8.

Everything above comes from the Natural Medicines adverse-effect record for Lactiplantibacillus Plantarum — expand a row for the licensed statement it rests on. We haven’t matched Brompheniramine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Brompheniramine.

Special populations

Lactiplantibacillus Plantarum in Pregnancy & Breastfeeding

Pregnancy Possibly Safe

When used orally and appropriately. Lactiplantibacillus plantarum (Lp299v, DSM 9843) has been used with apparent safety in doses of 10 billion colony-forming units (CFUs) daily in combination with iron, ascorbic acid, and folic acid daily from 10-12 weeks' gestation until delivery.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Brompheniramine Is Prescribed For, and What Lactiplantibacillus Plantarum Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Brompheniramine is a prescription medicine with approved uses on its FDA label. Lactiplantibacillus Plantarum is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Brompheniramine is prescribed for: Brompheniramine temporarily relieves allergy symptoms. The CVS Pharmacy oral liquid and Dimetapp oral solution list the same uses. Runny nose Sneezing Itchy, watery eyes due to hay fever Itching of the nose or throat

Lactiplantibacillus Plantarum has been studied for:

  • Common cold Natural Medicines rates the evidence for Lactiplantibacillus Plantarum: Possibly Effective Read what the research shows

    Lactiplantibacillus Plantarum for common cold

    A combination of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei seems to be beneficial for reducing the incidence or severity of the common cold. The effects of L. plantarum alone are unclear.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Brompheniramine on your own; if you are taking Lactiplantibacillus Plantarum for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Lactiplantibacillus Plantarum or Brompheniramine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lactiplantibacillus Plantarum or Brompheniramine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Brompheniramine

This page covers Lactiplantibacillus Plantarum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Brompheniramine page lists 43 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Alfalfa (moderate), Angelica Archangelica (moderate), Arrach (moderate) and Bergamot (moderate).

By severity: 1 major · 32 moderate · 10 minor.

From our pharmacist’s overview on the Brompheniramine page

“Brompheniramine, the sedating antihistamine in Dimetane and many combination cold medicines, deserves genuine care around supplements rather than a quick scan. The single major-rated entry is activated charcoal, which binds drugs in the gut and can sharply cut how much brompheniramine reaches your bloodstream.”

Reviewed by 2 · Jul 18, 2026

Open the Brompheniramine interaction page

How much people look this up

Where Lactiplantibacillus Plantarum and Brompheniramine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactiplantibacillus Plantarum
Top half

#617 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Brompheniramine
Top half

#1,059 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactiplantibacillus Plantarum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Lactiplantibacillus Plantarum and Brompheniramine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactiplantibacillus Plantarum

What is Lactiplantibacillus Plantarum?

  • Digestive health and regularity
  • Irritable bowel syndrome (IBS) symptoms
  • Bloating and gas
  • Immune support
  • Restoring gut bacteria after antibiotics

Lactiplantibacillus plantarum is a 'friendly' bacterium (probiotic) found in fermented foods and many supplements, studied mainly for digestive health. It is generally well tolerated in healthy people, but evidence is mixed and strain-specific, so benefits are not guaranteed. Talk to your pharmacist or doctor before starting, especially if you have a weakened immune system.

Lactiplantibacillus plantarum · Lactobacillaceae · Live bacterial cells (probiotic culture) · Capsules, tablets, powders, fermented foods, drinks, and combination probiotic products

An interaction check asks whether these two react with each other — it does not ask whether Lactiplantibacillus Plantarum is a good idea for someone in your situation. Here is what our Lactiplantibacillus Plantarum record says about it on its own.

Lactiplantibacillus Plantarum: dosing

There is no single official dose for L. plantarum. Probiotic amounts are usually measured in colony-forming units (CFU), and products vary widely in how much they contain and which strain they use.The best approach is to follow the directions on the product label. They can help you choose a reputable product and check that it is appropriate for your health situation.

From our Lactiplantibacillus Plantarum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactiplantibacillus Plantarum monograph & all interactions
Medication

About Brompheniramine

What Is Brompheniramine Used For?

Brand names: Lodrane, Dimetane

Brompheniramine temporarily relieves allergy symptoms. The CVS Pharmacy oral liquid and Dimetapp oral solution list the same uses.

  • Runny nose
  • Sneezing
  • Itchy, watery eyes due to hay fever
  • Itching of the nose or throat
See full Brompheniramine drug information
Keep checking

Other Drugs & Lactiplantibacillus Plantarum

Browse every other medication we’ve checked against Lactiplantibacillus Plantarum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactiplantibacillus Plantarum page.

No interaction 2,647 drugs checked — show the list

We also checked Lactiplantibacillus Plantarum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Lactiplantibacillus Plantarum list.

See the full Lactiplantibacillus Plantarum interactions page
See every supplement checked against Brompheniramine, ranked by severity
Evidence & sources

Lactiplantibacillus Plantarum References

The 12 references that drive our Lactiplantibacillus Plantarum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol 2012;18(30):4012-8.
  3. Krag A, Munkholm P, Israelsen H, von Ryberg B, Andersen KK, Bendtsen F. Profermin is efficacious in patients with active ulcerative colitis--a randomized controlled trial. Inflamm Bowel Dis. 2013;19(12):2584-92. PubMed
  4. Topcuoglu S, Gursoy T, Ovali F, Serce O, Karatekin G. A new risk factor for neonatal vancomycin-resistant Enterococcus colonisation: bacterial probiotics. J Matern Fetal Neonatal Med. 2015;28(12):1491-4. PubMed
  5. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  6. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  7. Axling U, Önning G, Martinsson Niskanen T, Larsson N, Hansson SR, Hulthén L. The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial. Acta Obstet Gynecol Scand
  8. Matsuura H, Kiura Y, Ito T, et al. Lactobacillus bacteremia: a diagnostic clue of rectal cancer. QJM. 2021;114(2):122-123. PubMed
  9. Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N. Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, doub
  10. Busch R, Gruenwald J, Dudek S. Randomized, double blind and placebo controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold. Food Nutr Sci 2013;4(11A):13-2. DOI
  11. Bengtsson J, Adlerberth I, Östblom A, Saksena P, Öresland T, Börjesson L. Effect of probiotics (Lactobacillus plantarum 299 plus Bifidobacterium Cure21) in patients with poor ileal pouch function: a randomised controlled trial. Scand J Gastroenterol 2016;
  12. Canaviri-Paz P, Oscarsson E, Kjellström A, Olsson H, Jois C, Håkansson Å. Effects on Microbiota Composition after Consumption of Quinoa Beverage Fermented by a Novel Xylose-Metabolizing L. plantarum Strain. Nutrients 2021;13(10):3318. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactiplantibacillus Plantarum and Brompheniramine Together: Common Questions

Is it safe to take Lactiplantibacillus Plantarum with Brompheniramine?
We do not list a known interaction between Lactiplantibacillus Plantarum and Brompheniramine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Lactiplantibacillus Plantarum and Brompheniramine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Lactiplantibacillus Plantarum in each. That is a conversation for your prescriber, especially if Brompheniramine is being adjusted to a target.
How was the Lactiplantibacillus Plantarum and Brompheniramine combination checked?
Interactions in our licensed database are recorded against drug classes. Brompheniramine is filed under 3 classifications, and Lactiplantibacillus Plantarum has documented interactions with 1 drug class — none of Brompheniramine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactiplantibacillus Plantarum interact with any other medications?
Yes. Lactiplantibacillus Plantarum has 182 documented drug interactions in our database — Brompheniramine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Brompheniramine interact with any supplements?
Yes. Brompheniramine has documented interactions with 43 supplements in our database — Lactiplantibacillus Plantarum is not one of them. The Brompheniramine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lactiplantibacillus Plantarum monograph Uses, safety profile, and every drug interaction in one place Brompheniramine drug information The full plain-English guide to this medication Brompheniramine supplement interactions Every supplement checked against Brompheniramine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Brompheniramine and Lactiplantibacillus Plantarum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.