Drug & supplement interaction

Lactobacillus Delbrueckii + Sevelamer

Sevelamer brand name: Renagel.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Lactobacillus Delbrueckii and Sevelamer in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Sevelamer states a food rule worth keeping to.

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Interaction report

Lactobacillus Delbrueckii and Sevelamer

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sevelamer and Lactobacillus Delbrueckii in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactobacillus Delbrueckii safety at a glance

Lactobacillus Delb... overall Use caution Generally well tolerated in healthy people, but people who are very ill or immunocompromised should be cautious.
Pregnancy Use caution Probiotics in food are likely fine, but supplement safety in pregnancy is not well studied, so check with your doctor.
Breastfeeding Use caution Limited specific data, so use only with guidance from your healthcare provider.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sevelamer and Lactobacillus Delbrueckii? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Sevelamer

Interactions in our licensed database are recorded against drug classes, not just single drug names. Sevelamer is filed under 2 classifications — including oral drugs. Lactobacillus Delbrueckii has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Sevelamer’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactobacillus Delbrueckii Does Interact With Other Medications

Lactobacillus Delbrueckii has 182 moderate known drug interactions in our database — Sevelamer isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. Sevelamer)
Taking anything else?

Check Another of Your Medications Against Lactobacillus Delbrueckii

Covers the 2,830 medications we’ve checked against Lactobacillus Delbrueckii. Pick one to open its full report.

What to actually watch for

What Lactobacillus Delbrueckii Itself Has Been Linked To

This is not an interaction — nothing below involves Sevelamer. It is the side-effect record for Lactobacillus Delbrueckii on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactobacillus Delbrueckii, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Trouble passing urine / A higher chance of infection Worth acting on Additional detail

    “Since Lactobacillus delbrueckii preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Lactobacillus Delbrueckii · Natural Medicines adverse-effect record, reported in prostatitis.

    6 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
    6. 112553. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Lactobacillus Delbrueckii — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Sevelamer’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Sevelamer column appears here.

How to take them

Some Sevelamer Products Have a Food Rule — Lactobacillus Delbrueckii Should Not Break It

At least one FDA label for a product containing Sevelamer says to take it with food. If you take Lactobacillus Delbrueckii on an empty stomach out of habit, keep them separate — and take Sevelamer with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Sevelamer products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Starting dose of Renvela is 0.8 or 1.6 grams administered orally three times per day with meals based on serum phosphorus levels for adult patients and based on body surface area (BSA) category for pediatric patients.

From the Dosage and Administration section of the FDA label we read for Sevelamer — where that label names a specific product, the instruction is that product's. See the Sevelamer drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Sevelamer

This page covers Lactobacillus Delbrueckii only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sevelamer page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 10 minor.

From our pharmacist’s overview on the Sevelamer page

“Kidney patients who take sevelamer (Renagel) to control phosphorus have a real reason to pause over this page, and activated charcoal is why. It carries the only major rating here because it can trap medicines in the gut and sharply cut the amount the body actually gets.”

Reviewed by 2 · Jul 18, 2026

Open the Sevelamer interaction page

One more smart check

Taking Lactobacillus Delbrueckii as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,200 real supplement products containing Lactobacillus Delbrueckii, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lactobacillus Delbrueckii. Even though Lactobacillus Delbrueckii itself has no known interaction with Sevelamer, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lactobacillus Delbrueckii and Sevelamer Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactobacillus Delbrueckii
Top 25%

#267 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sevelamer
Steady interest

#2,703 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactobacillus Delbrueckii reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lactobacillus Delbrueckii and Sevelamer records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactobacillus Delbrueckii

What is Lactobacillus Delbrueckii?

  • Digestive health
  • Lactose digestion support
  • Diarrhea
  • Gut microbiome balance
  • Immune support

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy people, but solid human evidence for most specific health claims is limited. Talk to a pharmacist or doctor before using it, especially if you have a weakened immune system or serious illness.

Lactobacillus delbrueckii · Lactobacillaceae · Live bacterial cultures (the whole microorganism) · Capsules, tablets, powders, fermented dairy products (yogurt, cheese), and multi-strain probiotic blends

An interaction check asks whether these two react with each other — it does not ask whether Lactobacillus Delbrueckii is a good idea for someone in your situation. Here is what our Lactobacillus Delbrueckii record says about it on its own.

Lactobacillus Delbrueckii: dosing

There is no standardized, official dose of Lactobacillus delbrueckii. Probiotic products are usually measured in colony-forming units (CFU), and the amount varies widely between products.The best approach is to follow the directions on the product label and not exceed the recommended amount. Storing the product as directed (some need refrigeration) helps keep the bacteria alive and effective.

From our Lactobacillus Delbrueckii monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactobacillus Delbrueckii monograph & all interactions
Medication

About Sevelamer

What Is Sevelamer Used For?

Brand name: Renagel

Sevelamer is used to control serum phosphorus (the level of phosphorus in your blood) in people with chronic kidney disease (CKD) who are on dialysis. High phosphorus is a serious problem for dialysis patients and needs to be managed with medication and diet.

Sevelamer carbonate tablets and Renvela® (sevelamer carbonate) oral suspension are approved for adults and children 6 years of age and older. Sevelamer hydrochloride tablets are indicated for adults with CKD on dialysis; their safety and effectiveness in CKD patients not on dialysis have not been studied.

See full Sevelamer drug information
Keep checking

Other Drugs & Lactobacillus Delbrueckii

Browse every other medication we’ve checked against Lactobacillus Delbrueckii — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactobacillus Delbrueckii page.

No interaction 2,647 drugs checked — show the list

We also checked Lactobacillus Delbrueckii against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Lactobacillus Delbrueckii list.

See the full Lactobacillus Delbrueckii interactions page
See every supplement checked against Sevelamer, ranked by severity
Evidence & sources

Lactobacillus Delbrueckii References

The 9 references that drive our Lactobacillus Delbrueckii monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
  8. Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
  9. Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactobacillus Delbrueckii and Sevelamer Together: Common Questions

Is it safe to take Lactobacillus Delbrueckii with Sevelamer?
We do not list a known interaction between Lactobacillus Delbrueckii and Sevelamer. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Lactobacillus Delbrueckii and Sevelamer at the same time of day?
At least one FDA label for a product containing Sevelamer says to take it with food. If you take Lactobacillus Delbrueckii on an empty stomach out of habit, keep them separate and take Sevelamer with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Sevelamer products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Lactobacillus Delbrueckii and Sevelamer combination checked?
Interactions in our licensed database are recorded against drug classes. Sevelamer is filed under 2 classifications, and Lactobacillus Delbrueckii has documented interactions with 1 drug class — none of Sevelamer's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactobacillus Delbrueckii interact with any other medications?
Yes. Lactobacillus Delbrueckii has 182 documented drug interactions in our database — Sevelamer is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Sevelamer interact with any supplements?
Yes. Sevelamer has documented interactions with 18 supplements in our database — Lactobacillus Delbrueckii is not one of them. The Sevelamer interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lactobacillus Delbrueckii monograph Uses, safety profile, and every drug interaction in one place Sevelamer drug information The full plain-English guide to this medication Sevelamer supplement interactions Every supplement checked against Sevelamer, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sevelamer and Lactobacillus Delbrueckii?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.