Drug & supplement interaction

Lactobacillus Delbrueckii + Losartan Potassium

Losartan Potassium brand name: Cozaar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Lactobacillus Delbrueckii and Losartan Potassium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Lactobacillus Delbrueckii and Losartan Potassium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Losartan Potassium and Lactobacillus Delbrueckii in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactobacillus Delbrueckii safety at a glance

Lactobacillus Delb... overall Use caution Generally well tolerated in healthy people, but people who are very ill or immunocompromised should be cautious.
Pregnancy Use caution Probiotics in food are likely fine, but supplement safety in pregnancy is not well studied, so check with your doctor.
Breastfeeding Use caution Limited specific data, so use only with guidance from your healthcare provider.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Losartan Potassium and Lactobacillus Delbrueckii? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Losartan Potassium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Losartan Potassium is filed under 7 classifications — including angiotensin receptor blockers (arbs), cytochrome p450 2c9 (cyp2c9) substrates, antihypertensive drugs. Lactobacillus Delbrueckii has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Losartan Potassium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactobacillus Delbrueckii Does Interact With Other Medications

Lactobacillus Delbrueckii has 182 moderate known drug interactions in our database — Losartan Potassium isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. Losartan Potassium)
Taking anything else?

Check Another of Your Medications Against Lactobacillus Delbrueckii

Covers the 2,830 medications we’ve checked against Lactobacillus Delbrueckii. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Lactobacillus Delbrueckii and Losartan Potassium May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    Lactobacillus Delbrueckii

    “Since Lactobacillus delbrueckii preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Lactobacillus Delbrueckii · Natural Medicines adverse-effect record, reported in prostatitis.

    6 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
    6. 112553. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed

    Losartan Potassium

    Listed in the ADVERSE REACTIONS section of the FDA label for Losartan Potassium. Read the label on DailyMed ›

Reported for Lactobacillus Delbrueckii but not commonly for Losartan Potassium: trouble passing urine.

Effects for Losartan Potassium come from the ADVERSE REACTIONS section of its FDA label; effects for Lactobacillus Delbrueckii come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Losartan Potassium Is Prescribed For, and What Lactobacillus Delbrueckii Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Losartan Potassium is a prescription medicine with approved uses on its FDA label. Lactobacillus Delbrueckii is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Losartan Potassium is prescribed for: Losartan treats high blood pressure (hypertension) in adults and children 6 years and older. Keeping blood pressure under control lowers the risk of serious events like stroke and heart attack. It is also used to reduce the risk of stroke in people who have high blood pressure and left ventricular hypertrophy (an enlarged heart muscle). Note: evidence suggests this stroke-risk benefit may not apply to Black patients.

Read the rest of what Losartan Potassium is prescribed for

Additionally, losartan treats diabetic nephropathy — kidney damage caused by type 2 diabetes — in people who also have high blood pressure.

Lactobacillus Delbrueckii has been studied for:

  • Diabetes studied, not established Lactobacillus Delbrueckii has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Lactobacillus Delbrueckii for diabetes

    Oral Lactobacillus delbrueckii has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Losartan Potassium on your own; if you are taking Lactobacillus Delbrueckii for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Lactobacillus Delbrueckii or Losartan Potassium

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lactobacillus Delbrueckii or Losartan Potassium, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Losartan Potassium

This page covers Lactobacillus Delbrueckii only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Losartan Potassium page lists 253 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and St. John's Wort (major).

By severity: 6 major · 205 moderate · 42 minor.

From our pharmacist’s overview on the Losartan Potassium page

“Losartan potassium (Cozaar) treats high blood pressure, and this is a list to respect, because six of its 253 supplement interactions carry a major rating. Most entries do one of two things.”

Reviewed by 2 · Jul 18, 2026

Open the Losartan Potassium interaction page

One more smart check

Taking Lactobacillus Delbrueckii as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,200 real supplement products containing Lactobacillus Delbrueckii, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lactobacillus Delbrueckii. Even though Lactobacillus Delbrueckii itself has no known interaction with Losartan Potassium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lactobacillus Delbrueckii and Losartan Potassium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactobacillus Delbrueckii
Top 25%

#273 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Losartan Potassium
Top 1%

#12 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactobacillus Delbrueckii reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Lactobacillus Delbrueckii and Losartan Potassium records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactobacillus Delbrueckii

What is Lactobacillus Delbrueckii?

  • Digestive health
  • Lactose digestion support
  • Diarrhea
  • Gut microbiome balance
  • Immune support

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy people, but solid human evidence for most specific health claims is limited. Talk to a pharmacist or doctor before using it, especially if you have a weakened immune system or serious illness.

Lactobacillus delbrueckii · Lactobacillaceae · Live bacterial cultures (the whole microorganism) · Capsules, tablets, powders, fermented dairy products (yogurt, cheese), and multi-strain probiotic blends

An interaction check asks whether these two react with each other — it does not ask whether Lactobacillus Delbrueckii is a good idea for someone in your situation. Here is what our Lactobacillus Delbrueckii record says about it on its own.

Lactobacillus Delbrueckii: dosing

There is no standardized, official dose of Lactobacillus delbrueckii. Probiotic products are usually measured in colony-forming units (CFU), and the amount varies widely between products.The best approach is to follow the directions on the product label and not exceed the recommended amount. Storing the product as directed (some need refrigeration) helps keep the bacteria alive and effective.

From our Lactobacillus Delbrueckii monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactobacillus Delbrueckii monograph & all interactions
Medication

About Losartan

What Is Losartan Used For?

Brand name: Cozaar

Losartan treats high blood pressure (hypertension) in adults and children 6 years and older. Keeping blood pressure under control lowers the risk of serious events like stroke and heart attack.

It is also used to reduce the risk of stroke in people who have high blood pressure and left ventricular hypertrophy (an enlarged heart muscle). Note: evidence suggests this stroke-risk benefit may not apply to Black patients. Additionally, losartan treats diabetic nephropathy — kidney damage caused by type 2 diabetes — in people who also have high blood pressure.

See full Losartan drug information
Keep checking

Other Drugs & Lactobacillus Delbrueckii

Browse every other medication we’ve checked against Lactobacillus Delbrueckii — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactobacillus Delbrueckii page.

No interaction 2,647 drugs checked — show the list

We also checked Lactobacillus Delbrueckii against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Lactobacillus Delbrueckii list.

See the full Lactobacillus Delbrueckii interactions page
See every supplement checked against Losartan Potassium, ranked by severity
Evidence & sources

Lactobacillus Delbrueckii References

The 9 references that drive our Lactobacillus Delbrueckii monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
  8. Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
  9. Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactobacillus Delbrueckii and Losartan Potassium Together: Common Questions

Is it safe to take Lactobacillus Delbrueckii with Losartan Potassium?
We do not list a known interaction between Lactobacillus Delbrueckii and Losartan Potassium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Lactobacillus Delbrueckii and Losartan Potassium have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Lactobacillus Delbrueckii and Losartan Potassium used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Lactobacillus Delbrueckii in each. That is a conversation for your prescriber, especially if Losartan Potassium is being adjusted to a target.
How was the Lactobacillus Delbrueckii and Losartan Potassium combination checked?
Interactions in our licensed database are recorded against drug classes. Losartan Potassium is filed under 7 classifications, and Lactobacillus Delbrueckii has documented interactions with 1 drug class — none of Losartan Potassium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactobacillus Delbrueckii interact with any other medications?
Yes. Lactobacillus Delbrueckii has 182 documented drug interactions in our database — Losartan Potassium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Losartan Potassium interact with any supplements?
Yes. Losartan Potassium has documented interactions with 253 supplements in our database — Lactobacillus Delbrueckii is not one of them. The Losartan Potassium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lactobacillus Delbrueckii monograph Uses, safety profile, and every drug interaction in one place Losartan drug information The full plain-English guide to this medication Losartan Potassium supplement interactions Every supplement checked against Losartan Potassium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Losartan Potassium and Lactobacillus Delbrueckii?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.