Drug & supplement interaction

Laminaria + Amiloride

Amiloride brand names: Midamor, Amilamont.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Laminaria has a moderate interaction with Amiloride. Theoretically, laminaria might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Laminaria and Amiloride

Here is the interaction we found between these two, with the evidence behind it.

Moderate

POTASSIUM-SPARING DIURETICS

Why this applies to Amiloride

Amiloride falls under POTASSIUM-SPARING DIURETICS — the group Laminaria interacts with.

Theoretically, laminaria might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Laminaria contains potassium.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing to know about pairing kelp (Laminaria) with amiloride. Amiloride is a potassium-sparing water pill, which means it helps your body hold onto potassium instead of flushing it out. Kelp naturally contains some potassium of its own, so in theory, stacking the two together could nudge your potassium level up too high, a state called hyperkalemia.

If potassium climbs too far, it can cause muscle weakness, tingling, a slow or irregular heartbeat, or feeling unusually tired. To be fair, this concern is mostly theoretical and based on how these things work, not on strong studies. Still, it's worth a quick chat with your pharmacist or doctor before starting a kelp supplement, especially since they may already be watching your potassium.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Laminaria Also Interacts With Other Medications

Laminaria has 68 moderate known drug interactions in our database — the Amiloride one above is one of them. If you take anything else, check it against the full list below.

Moderate 68 No known interaction 2,762 (incl. Amiloride)
Taking anything else?

Check Another of Your Medications Against Laminaria

Covers the 2,830 medications we’ve checked against Laminaria. Pick one to open its full report.

From our Q&A

Questions About Laminaria or Amiloride

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Laminaria or Amiloride, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amiloride

This page covers Laminaria only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amiloride page lists 143 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Tyramine (major) and Adrafinil (moderate).

By severity: 4 major · 116 moderate · 23 minor.

From our pharmacist’s overview on the Amiloride page

“Amiloride (Midamor) is a water pill that lowers blood pressure while holding onto potassium, and both of those jobs give supplements openings to cause trouble, so I would read this list with real care. Four of the 143 ingredients on file carry a major rating, including tyramine and American mistletoe, which can push blood pressure up a…”

Reviewed by 2 · Jul 18, 2026

Open the Amiloride interaction page

One more smart check

Taking Laminaria as Part of a Dietary Supplement Product? Check It for Interactions

We hold 229 real supplement products containing Laminaria, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Laminaria. Your product may carry other ingredients that interact with Amiloride too, on top of Laminaria — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Laminaria and Amiloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Laminaria
Steady interest

#1,017 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amiloride
Top half

#711 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Laminaria

What is Laminaria?

  • Source of dietary iodine
  • Thyroid support
  • Cervical dilation (medical procedure)
  • Weight management
  • Digestive and detox supplements
  • General nutrition (vitamins and minerals)

Laminaria is a type of brown seaweed (kelp) that is very rich in iodine and is also used in medical settings as a natural cervical dilator. Because its iodine content can be high and variable, supplements may upset thyroid function, so it should be used cautiously and under professional guidance. Always talk with your pharmacist or doctor before using kelp products, especially if you have a thyroid condition.

Read the full Laminaria monograph & all interactions
Medication

About Amiloride

What Is Amiloride Used For?

Brand names: Midamor, Amilamont

Amiloride is used together with other diuretics (water pills) to treat congestive heart failure and high blood pressure (hypertension). It is added to a thiazide or similar diuretic to either restore low potassium levels or prevent them from dropping dangerously in the first place.

It is especially useful for people who are at particular risk if their potassium falls too low — for example, those taking digoxin or those with significant heart rhythm problems. Amiloride is rarely used on its own, as its diuretic and blood-pressure-lowering effects are weak compared with other diuretics.

See full Amiloride drug information
Keep checking

Other Drugs & Laminaria

Browse every other medication we’ve checked against Laminaria — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
68Moderate
0Minor
2,761No known interaction
68 Moderate 2,761 No interaction
Moderate

68 interactions

Showing 60 of 68 moderate interactions — see all 68 on the Laminaria page.

No interaction 2,761 drugs checked — show the list

We also checked Laminaria against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,761 medications checked with no known interaction — see the full Laminaria list.

See the full Laminaria interactions page
See every supplement checked against Amiloride, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
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Pharmacist Counseling Corner

Taking Laminaria and Amiloride Together: Common Questions

Can you take Laminaria with Amiloride?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Laminaria and Amiloride interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Amiloride and Laminaria?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.