Drug & supplement interaction

Laminaria + Amiodarone

Amiodarone brand names: Pacerone, Cordarone.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Laminaria has a moderate interaction with Amiodarone. Theoretically, combining laminaria with amiodarone might cause excessively high iodine levels.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Laminaria and Amiodarone

Here is the interaction we found between these two, with the evidence behind it.

Moderate

AMIODARONE (Cordarone)

Theoretically, combining laminaria with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with laminaria supplements, some of which may contain as much as 1000 mcg iodine, might increase the risk of adverse effects from iodine, including altered thyroid function.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's something a lot of people don't realize about amiodarone: it's loaded with iodine. By weight, it's roughly 37% iodine, so taking it already gives your body a big iodine load. Kelp like Laminaria is also very rich in iodine, and the amount can vary a lot from product to product. Stacking the two together means even more iodine going into your system.

The concern is that this combined iodine could throw off your thyroid, pushing it either too high (jitters, racing heart, weight loss) or too low (fatigue, weight gain, feeling cold). Amiodarone alone can already affect the thyroid, so adding kelp just piles on. This worry is theoretical, based on the iodine in both, not strong studies. Still, I'd skip the kelp supplement and check with your doctor or pharmacist first.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Eliason BC. Transient hyperthyroidism in a patient taking dietary supplements containing kelp. J Am Board Fam Pract 1998;11:478-80. PubMed
  2. Miyai K, Tokushige T, Kondo M; Iodine Research Group. Suppression of thyroid function during ingestion of seaweed "Kombu" (Laminaria japonoca) in normal Japanese adults. Endocr J. 2008 Dec;55(6):1103-8. Epub 2008 Aug 9.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Laminaria Also Interacts With Other Medications

Laminaria has 68 moderate known drug interactions in our database — the Amiodarone one above is one of them. If you take anything else, check it against the full list below.

Moderate 68 No known interaction 2,762 (incl. Amiodarone)
Taking anything else?

Check Another of Your Medications Against Laminaria

Covers the 2,830 medications we’ve checked against Laminaria. Pick one to open its full report.

From our Q&A

Questions About Laminaria or Amiodarone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Laminaria or Amiodarone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amiodarone

This page covers Laminaria only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amiodarone page lists 210 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).

By severity: 11 major · 163 moderate · 36 minor.

From our pharmacist’s overview on the Amiodarone page

“Amiodarone (Pacerone, Cordarone) treats dangerous heart rhythms, and this is one supplement list I would genuinely be careful with. Of the 210 ingredients on file, 11 carry a major rating, and the everyday one is grapefruit, which blocks the liver enzyme that clears amiodarone and can push the drug's level higher than intended.”

Reviewed by 2 · Jul 18, 2026

Open the Amiodarone interaction page

One more smart check

Taking Laminaria as Part of a Dietary Supplement Product? Check It for Interactions

We hold 229 real supplement products containing Laminaria, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Laminaria. Your product may carry other ingredients that interact with Amiodarone too, on top of Laminaria — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Laminaria and Amiodarone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Laminaria
Steady interest

#1,017 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amiodarone
Top half

#833 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Laminaria

What is Laminaria?

  • Source of dietary iodine
  • Thyroid support
  • Cervical dilation (medical procedure)
  • Weight management
  • Digestive and detox supplements
  • General nutrition (vitamins and minerals)

Laminaria is a type of brown seaweed (kelp) that is very rich in iodine and is also used in medical settings as a natural cervical dilator. Because its iodine content can be high and variable, supplements may upset thyroid function, so it should be used cautiously and under professional guidance. Always talk with your pharmacist or doctor before using kelp products, especially if you have a thyroid condition.

Read the full Laminaria monograph & all interactions
Medication

About Amiodarone

What Is Amiodarone Used For?

Brand names: Pacerone, Cordarone

Amiodarone is prescribed for adults with serious, life-threatening heart-rhythm problems that haven't responded to other medications. Specifically, it's used for two dangerous arrhythmias (abnormal heartbeats): recurrent ventricular fibrillation (a chaotic, potentially fatal heart rhythm) and recurrent ventricular tachycardia (a dangerously fast heart rhythm that causes unstable blood pressure).

Because amiodarone comes with significant risks, doctors reserve it for situations where other options haven't worked or can't be tolerated. It is not a first-choice medication — it's a last-resort tool for serious, life-threatening conditions.

See full Amiodarone drug information
Keep checking

Other Drugs & Laminaria

Browse every other medication we’ve checked against Laminaria — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
68Moderate
0Minor
2,761No known interaction
68 Moderate 2,761 No interaction
Moderate

68 interactions

Showing 60 of 68 moderate interactions — see all 68 on the Laminaria page.

No interaction 2,761 drugs checked — show the list

We also checked Laminaria against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,761 medications checked with no known interaction — see the full Laminaria list.

See the full Laminaria interactions page
See every supplement checked against Amiodarone, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Laminaria monograph › Uses, safety, and every drug interaction in one place Amiodarone supplement interactions › Every supplement checked against Amiodarone, ranked by severity Amiodarone drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Laminaria and Amiodarone Together: Common Questions

Can you take Laminaria with Amiodarone?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Laminaria and Amiodarone interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Amiodarone and Laminaria?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.