Drug & supplement interaction

Laminaria + Dabrafenib

Dabrafenib brand name: Tafinlar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Laminaria and Dabrafenib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Dabrafenib states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Laminaria and Dabrafenib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dabrafenib and Laminaria in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Laminaria safety at a glance

Laminaria overall Use caution Generally safe as food, but supplements can deliver very high, variable amounts of iodine that may affect the thyroid.
Pregnancy Possibly Unsafe When used intravaginally for cervical ripening; there is an increased risk of parental and neonatal infection. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally because of potential toxicity. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dabrafenib and Laminaria? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Dabrafenib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dabrafenib is filed under 4 classifications — including cytochrome p450 2c8 (cyp2c8) substrates, cytochrome p450 3a4 (cyp3a4) inducers, cytochrome p450 3a4 (cyp3a4) substrates. Laminaria has documented interactions with 6 drug classes — the most serious being ace inhibitors (aceis) (moderate), amiodarone (cordarone) (moderate) and antithyroid drugs (moderate) — and none of Dabrafenib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Laminaria Does Interact With Other Medications

Laminaria has 69 moderate known drug interactions in our database — Dabrafenib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 69 No known interaction 2,761 (incl. Dabrafenib)
Taking anything else?

Check Another of Your Medications Against Laminaria

Covers the 2,830 medications we’ve checked against Laminaria. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Laminaria and Dabrafenib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • Bleeding or bruising Worth acting on Additional detail

    Laminaria

    “Intravaginally, laminaria used for cervical ripening can cause pelvic cramps and cervical bleeding. Uterine contractions associated with laminaria use have been implicated in fetal hypoxia and subsequent intrauterine death (6). Use of endocervical laminaria tents has been associated with possible rupture of the cervical wall and subsequent neonatal and parental infection (6,8945).”

    Laminaria · Natural Medicines adverse-effect record, reported in bleeding.

    2 sources cited
    1. 8945. Kazzi GM, Bottoms SF, Rosen MG. Efficacy and safety of Laminaria digitata for preinduction ripening of the cervix. Obstet Gynecol 1982;60:440-3..
    2. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

    Dabrafenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Dabrafenib. Read the label on DailyMed ›

  • A higher chance of infection Worth acting on Additional detail

    Laminaria

    Recorded for Laminaria in the same Natural Medicines adverse-effect record shown under Bleeding or bruising above.

    Dabrafenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Dabrafenib. Read the label on DailyMed ›

  • Acne Additional detail

    Laminaria

    “Orally, laminaria has been linked to a report of induced or exacerbated acne.”

    Laminaria · Natural Medicines adverse-effect record, reported in acne.

    1 source cited
    1. 9555. Harrell BL, Rudolph AH. Letter: Kelp diet: A cause of acneform eruption. Arch Dermatol 1976;112:560.

    Dabrafenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Dabrafenib. Read the label on DailyMed ›

  • Tiredness / Diarrhea / A skin rash / Vomiting / Headache Additional detail

    Laminaria

    “Laminaria concentrates arsenic from the ocean. In one case, use of an oral laminaria supplement for several months resulted in symptoms of arsenic poisoning including headache, weakness, fatigue, worsening memory loss, rash, nail damage, diarrhea, and vomiting. Urinary arsenic levels were elevated.”

    Laminaria · Natural Medicines adverse-effect record, reported in arsenic poisoning.

    3 sources cited
    1. 15588. Amster E, Tiwary A, Schenker MB. Case report: potential arsenic toxicosis secondary to herbal kelp supplement. Environ Health Perspect 2007;115:606-8. PubMed
    2. 645. Pye KG, Kelsey SM, House IM, et al. Severe dyserythropoeisis and autoimmune thrombocytopenia associated with ingestion of kelp supplement. Lancet 1992;339:1540.
    3. 10275. Norman JA, Pickford CJ, Sanders TW, Waller M. Human intake of arsenic and iodine from seaweed-based food supplements and health foods available in the UK. Food Addit Contam 1988;5:103-9.. PubMed

    Dabrafenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Dabrafenib. Read the label on DailyMed ›

Reported for Laminaria but not commonly for Dabrafenib: a change in thyroid levels, memory problems and a severe allergic reaction.

Effects for Dabrafenib come from the ADVERSE REACTIONS section of its FDA label; effects for Laminaria come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Laminaria in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used intravaginally for cervical ripening; there is an increased risk of parental and neonatal infection.

Pregnancy Likely Unsafe

When used intravaginally to induce labor; use has been associated with endometriosis, neonatal sepsis, fetal hypoxia, and intrauterine death.

Pregnancy Unsafe

When used orally due to potential hormonal effects; avoid using.

Lactation Likely Unsafe

When used orally because of potential toxicity.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Dabrafenib Products Have a Food Rule — Laminaria Should Not Break It

At least one FDA label for a product containing Dabrafenib says to take it on an empty stomach. Most supplements — Laminaria included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Dabrafenib on its own and move Laminaria to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Dabrafenib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

TAFINLAR Capsules Take TAFINLAR capsules on an empty stomach (at least 1 hour before or 2 hours after a meal) [see Clinical Pharmacology (12.3)] .

From the Dosage and Administration section of the FDA label we read for Dabrafenib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Dabrafenib Is Prescribed For, and What Laminaria Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Dabrafenib is a prescription medicine with approved uses on its FDA label. Laminaria is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Dabrafenib is prescribed for: Dabrafenib is used to treat cancers that carry a specific change (mutation) in the BRAF gene — most often called a BRAF V600E or V600K mutation. These mutations cause cancer cells to grow out of control. Before starting this medicine, a tumor test must confirm the mutation is present. It can be used alone or — more commonly — paired with another targeted drug, trametinib.

Read the rest of what Dabrafenib is prescribed for

Conditions it treats include advanced or inoperable melanoma (skin cancer), certain lung cancers, anaplastic thyroid cancer, low-grade brain tumors (glioma) in children, and other solid tumors with the same mutation that haven't responded to prior treatment.

Laminaria has been studied for:

  • Cancer studied, not established Laminaria has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Laminaria for cancer

    Although there has been interest in using oral laminaria for cancer prevention, there is insufficient reliable information about the clinical effects of laminaria for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Dabrafenib on your own; if you are taking Laminaria for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Dabrafenib

This page covers Laminaria only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dabrafenib page lists 154 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 112 moderate · 39 minor.

Open the Dabrafenib interaction page

One more smart check

Taking Laminaria as Part of a Dietary Supplement Product? Check It for Interactions

We hold 229 real supplement products containing Laminaria, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Laminaria. Even though Laminaria itself has no known interaction with Dabrafenib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Laminaria and Dabrafenib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Laminaria
Top half

#633 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dabrafenib
Steady interest

#1,464 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Laminaria reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Laminaria and Dabrafenib records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Laminaria

What is Laminaria?

  • Source of dietary iodine
  • Thyroid support
  • Cervical dilation (medical procedure)
  • Weight management
  • Digestive and detox supplements
  • General nutrition (vitamins and minerals)

Laminaria is a type of brown seaweed (kelp) that is very rich in iodine and is also used in medical settings as a natural cervical dilator. Because its iodine content can be high and variable, supplements may upset thyroid function, so it should be used cautiously and under professional guidance. Always talk with your pharmacist or doctor before using kelp products, especially if you have a thyroid condition.

Laminaria spp. · Laminariaceae · Whole thallus (dried seaweed/kelp); processed stems used for cervical dilators · Dried seaweed (food), powder, capsules, tablets, and medical cervical dilator sticks

An interaction check asks whether these two react with each other — it does not ask whether Laminaria is a good idea for someone in your situation. Here is what our Laminaria record says about it on its own.

Laminaria: dosing

There is no well-established standard supplement dose for Laminaria, and because iodine content varies so much between products, a "safe" amount is hard to define. The main safety limit to keep in mind is total daily iodine intake, which can be easy to exceed with kelp supplements.If you choose to use a kelp product, follow the directions on the label and pick a brand that lists its iodine content and is tested for heavy metals. Do not assume more is better. Medical Laminaria dilators are not dosed by the patient; they are placed and managed entirely by a healthcare professional.

From our Laminaria monograph — the full record covers uses, side effects and every documented interaction.

Read the full Laminaria monograph & all interactions
Medication

About Dabrafenib

What Is Dabrafenib Used For?

Brand name: Tafinlar

Dabrafenib is used to treat cancers that carry a specific change (mutation) in the BRAF gene — most often called a BRAF V600E or V600K mutation. These mutations cause cancer cells to grow out of control. Before starting this medicine, a tumor test must confirm the mutation is present.

It can be used alone or — more commonly — paired with another targeted drug, trametinib. Conditions it treats include advanced or inoperable melanoma (skin cancer), certain lung cancers, anaplastic thyroid cancer, low-grade brain tumors (glioma) in children, and other solid tumors with the same mutation that haven't responded to prior treatment.

See full Dabrafenib drug information
Keep checking

Other Drugs & Laminaria

Browse every other medication we’ve checked against Laminaria — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
69Moderate
0Minor
2,760No known interaction
69 Moderate 2,760 No interaction
Moderate

69 interactions

Showing 60 of 69 moderate interactions — see all 69 on the Laminaria page.

No interaction 2,760 drugs checked — show the list

We also checked Laminaria against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,760 medications checked with no known interaction — see the full Laminaria list.

See the full Laminaria interactions page
See every supplement checked against Dabrafenib, ranked by severity
Evidence & sources

Laminaria References

The 9 references that drive our Laminaria monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Pye KG, Kelsey SM, House IM, et al. Severe dyserythropoeisis and autoimmune thrombocytopenia associated with ingestion of kelp supplement. Lancet 1992;339:1540.
  4. Kazzi GM, Bottoms SF, Rosen MG. Efficacy and safety of Laminaria digitata for preinduction ripening of the cervix. Obstet Gynecol 1982;60:440-3..
  5. Harrell BL, Rudolph AH. Letter: Kelp diet: A cause of acneform eruption. Arch Dermatol 1976;112:560.
  6. Eliason BC. Transient hyperthyroidism in a patient taking dietary supplements containing kelp. J Am Board Fam Pract 1998;11:478-80. PubMed
  7. Norman JA, Pickford CJ, Sanders TW, Waller M. Human intake of arsenic and iodine from seaweed-based food supplements and health foods available in the UK. Food Addit Contam 1988;5:103-9.. PubMed
  8. Amster E, Tiwary A, Schenker MB. Case report: potential arsenic toxicosis secondary to herbal kelp supplement. Environ Health Perspect 2007;115:606-8. PubMed
  9. Miyai K, Tokushige T, Kondo M; Iodine Research Group. Suppression of thyroid function during ingestion of seaweed "Kombu" (Laminaria japonoca) in normal Japanese adults. Endocr J. 2008 Dec;55(6):1103-8. Epub 2008 Aug 9.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Laminaria and Dabrafenib Together: Common Questions

Is it safe to take Laminaria with Dabrafenib?
We do not list a known interaction between Laminaria and Dabrafenib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Laminaria and Dabrafenib have any of the same side effects?
Yes — our sources link each of them separately to 8 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Laminaria and Dabrafenib at the same time of day?
At least one FDA label for a product containing Dabrafenib says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Dabrafenib on its own and move Laminaria to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Are Laminaria and Dabrafenib used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Laminaria in each. That is a conversation for your prescriber, especially if Dabrafenib is being adjusted to a target.
How was the Laminaria and Dabrafenib combination checked?
Interactions in our licensed database are recorded against drug classes. Dabrafenib is filed under 4 classifications, and Laminaria has documented interactions with 6 drug classes — none of Dabrafenib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Laminaria interact with any other medications?
Yes. Laminaria has 69 documented drug interactions in our database — Dabrafenib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Dabrafenib interact with any supplements?
Yes. Dabrafenib has documented interactions with 154 supplements in our database — Laminaria is not one of them. The Dabrafenib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Laminaria monograph Uses, safety profile, and every drug interaction in one place Dabrafenib drug information The full plain-English guide to this medication Dabrafenib supplement interactions Every supplement checked against Dabrafenib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dabrafenib and Laminaria?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.