Drug & supplement interaction

Maidenhair Fern + Zolmitriptan

Zolmitriptan brand name: Zomig.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Maidenhair Fern and Zolmitriptan in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Maidenhair Fern and Zolmitriptan

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Zolmitriptan and Maidenhair Fern in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Maidenhair Fern at all — not against Zolmitriptan, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Maidenhair Fern safety at a glance

Maidenhair Fern overall Use caution Used traditionally in foods and teas, but modern safety data in humans are limited.
Pregnancy Unsafe When used orally. Maidenhair fern is contraindicated in pregnancy. Read the full pregnancy detail
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Zolmitriptan and Maidenhair Fern? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Zolmitriptan’s Own FDA Label Lists

This is not an interaction — none of it involves Maidenhair Fern. These are the most notable effects listed in the ADVERSE REACTIONS section of Zolmitriptan’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Serotonin syndrome Worth acting on
  • Memory problems Worth acting on
  • Trouble swallowing Worth acting on
  • A heart attack Worth acting on
  • Hallucinations Worth acting on
  • Fainting Worth acting on
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • Raised blood pressure Worth acting on
  • A severe allergic reaction Worth acting on

Showing the 10 most notable of 29 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Zolmitriptan. Read the label on DailyMed › Maidenhair Fern’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Maidenhair Fern side to compare — that is a limit of the record, not a statement that Maidenhair Fern has no side effects.

Special populations

Maidenhair Fern in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally. Maidenhair fern is contraindicated in pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Zolmitriptan

This page covers Maidenhair Fern only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Zolmitriptan page lists 50 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 31 moderate · 11 minor.

From our pharmacist’s overview on the Zolmitriptan page

“Zolmitriptan (Zomig) treats migraines by working on serotonin and tightening blood vessels, and that mechanism is exactly why this list deserves real vigilance. Twenty of the 50 supplements on file, including everyday items like 5-HTP and black cohosh, also raise serotonin, and stacking them on a triptan can push someone toward seroton…”

Reviewed by 2 · Jul 18, 2026

Open the Zolmitriptan interaction page

One more smart check

Taking Maidenhair Fern as Part of a Dietary Supplement Product? Check It for Interactions

We hold 18 real supplement products containing Maidenhair Fern, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Maidenhair Fern. Even though Maidenhair Fern itself has no known interaction with Zolmitriptan, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Maidenhair Fern and Zolmitriptan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Maidenhair Fern
Steady interest

#1,278 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Zolmitriptan
Steady interest

#2,087 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Maidenhair Fern reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Maidenhair Fern and Zolmitriptan records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Maidenhair Fern

What is Maidenhair Fern?

  • Cough and respiratory complaints
  • Hair and scalp health
  • Cold and flu symptoms
  • Mild urinary complaints
  • Menstrual complaints

Maidenhair fern is a traditional herb used mainly in teas and syrups for coughs and respiratory complaints, but high-quality human studies are lacking. Because its safety has not been well studied, it is best to use it cautiously and to avoid it during pregnancy and breastfeeding.

Adiantum capillus-veneris · Pteridaceae · Fronds (leaves) and the whole above-ground plant · Tea (infusion), syrup, dried herb, liquid extract, and as an ingredient in traditional cough preparations

An interaction check asks whether these two react with each other — it does not ask whether Maidenhair Fern is a good idea for someone in your situation. Here is what our Maidenhair Fern record says about it on its own.

Maidenhair Fern: dosing

There is no standardized or well-established dose for maidenhair fern. Traditional use is mostly as a tea made from the dried fronds or as a syrup, but exact safe and effective amounts have not been confirmed by research.If you choose to use it, follow the directions on the product label and do not exceed the suggested amount. A pharmacist can help you decide whether it is appropriate for you and review it alongside your other medicines and supplements.

From our Maidenhair Fern monograph — the full record covers uses, side effects and every documented interaction.

Read the full Maidenhair Fern monograph & all interactions
Medication

About Zolmitriptan

What Is Zolmitriptan Used For?

Brand name: Zomig

Zolmitriptan is used to treat migraine headaches as they happen — it is not a daily preventive medication. Tablets (including Zomig tablets) and orally disintegrating tablets are approved for acute migraine treatment in adults. Zolmitriptan nasal spray and Zomig Nasal Spray are also approved for adults and for adolescents 12 years of age and older.

It works for migraines with or without aura (the visual or sensory changes some people get before a headache). It is not approved for cluster headaches, and it should only be used once a migraine diagnosis has been clearly established by a healthcare provider.

See full Zolmitriptan drug information
Keep checking

Other Drugs & Maidenhair Fern

Browse every other medication we’ve checked against Maidenhair Fern — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Maidenhair Fern References

The 2 references that drive our Maidenhair Fern monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Maidenhair Fern and Zolmitriptan Together: Common Questions

Is it safe to take Maidenhair Fern with Zolmitriptan?
We do not list a known interaction between Maidenhair Fern and Zolmitriptan. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Zolmitriptan interact with any supplements?
Yes. Zolmitriptan has documented interactions with 50 supplements in our database — Maidenhair Fern is not one of them. The Zolmitriptan interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Zolmitriptan and Maidenhair Fern?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.