Monterey Pine + Riociguat
Riociguat brand name: Adempas.
We found no known interaction between Monterey Pine and Riociguat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Monterey Pine and Riociguat
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Riociguat and Monterey Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Monterey Pine at all — not against Riociguat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Monterey Pine safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Riociguat
This page covers Monterey Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Riociguat page lists 230 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and St. John's Wort (major).
By severity: 6 major · 187 moderate · 37 minor.
From our pharmacist’s overview on the Riociguat page
“Riociguat (Adempas) works by relaxing the blood vessels in your lungs, which also lowers blood pressure, so I read this list of 230 supplements and herbs with real concern, and the six rated major are what to understand first. Grapefruit can push riociguat levels up and intensify its effect, while St.”
Reviewed by 2 · Jul 18, 2026
Taking Monterey Pine as Part of a Dietary Supplement Product? Check It for Interactions
We hold 43 real supplement products containing Monterey Pine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Monterey Pine. Even though Monterey Pine itself has no known interaction with Riociguat, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Monterey Pine and Riociguat Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#686 of 1,452 supplements looked up here in the last 7 days
#2,123 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Monterey Pine reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Monterey Pine and Riociguat records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Monterey Pine
What is Monterey Pine?
- Antioxidant support
- Skin and aging concerns
- Circulation support
- Inflammation
- Respiratory comfort
Monterey Pine is mainly a timber tree, and human evidence for its use as a supplement is very limited. Some pine bark extracts are studied for antioxidant effects, but most claims specific to Monterey Pine are not well proven. Talk to a pharmacist or doctor before using any pine-based product.
Pinus radiata · Pinaceae · Bark, needles, and essential oil · Bark extract supplements, essential oil, needle tea
An interaction check asks whether these two react with each other — it does not ask whether Monterey Pine is a good idea for someone in your situation. Here is what our Monterey Pine record says about it on its own.
Monterey Pine: dosing
There is no established standard dose for Monterey Pine. Because products vary widely in strength and form, a safe, proven amount has not been set.If you choose to use a pine-derived product, follow the directions on the label and do not exceed them. Essential oils are for external or aromatherapy use only unless a professional advises otherwise.
From our Monterey Pine monograph — the full record covers uses, side effects and every documented interaction.
About Riociguat
What Is Riociguat Used For?
Brand name: Adempas
Riociguat tablets — sold as Adempas and under the generic name Riociguat — are used to treat adults with two types of pulmonary hypertension (high blood pressure in the lungs).
The first is chronic thromboembolic pulmonary hypertension (CTEPH), a condition caused by blood clots in the lung arteries, either after surgery or when surgery is not an option. The second is pulmonary arterial hypertension (PAH), where the arteries carrying blood to the lungs are narrowed or blocked. In both conditions, riociguat helps improve exercise ability and functional status, and in PAH it also helps slow the disease from getting worse.
Most-Reported Side Effects for Riociguat
From FAERS, the FDA’s public side-effect reporting system (32,415 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Monterey Pine
Browse every other medication we’ve checked against Monterey Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Monterey Pine against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Monterey Pine list.
Monterey Pine References
The 1 references that drive our Monterey Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Burry, J. N. Environmental dermatitis: contact dermatitis from Pinus radiata. Med J Aust. 7-2-1977;2(1):13-14. DOI
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Riociguat Is Linked to Lower Levels of One Nutrient
Natural Medicines records Riociguat as a medicine that can lower these. This is not an interaction with Monterey Pine — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Riociguat nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Monterey Pine and Riociguat Together: Common Questions
Is it safe to take Monterey Pine with Riociguat?
Does Riociguat interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Riociguat and Monterey Pine?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.