Drug & supplement interaction

Mountain Ash + Interferon Beta-1a

Interferon Beta-1a brand names: Rebif, Avonex.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Mountain Ash and Interferon Beta-1a in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mountain Ash and Interferon Beta-1a

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Interferon Beta-1a and Mountain Ash in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mountain Ash safety at a glance

Mountain Ash overall Use caution Cooked berries are generally well tolerated in food amounts, but raw berries can cause stomach upset and evidence for medicinal use is limited.

Pregnancy Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full pregnancy detail

Breastfeeding Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Interferon Beta-1a and Mountain Ash? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Interferon Beta-1a

Interactions in our licensed database are recorded against drug classes, not just single drug names. Interferon Beta-1a is filed under 2 classifications — photosensitizing drugs, hepatotoxic drugs. Mountain Ash has documented interactions with 1 drug class — the most serious being nephrotoxic drugs (moderate) — and none of Interferon Beta-1a’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Mountain Ash Does Interact With Other Medications

Mountain Ash has 355 moderate known drug interactions in our database — Interferon Beta-1a isn’t one of them. If you take anything else, check it against the full list below.

Moderate 355 No known interaction 2,475 (incl. Interferon Beta-1a)

Taking anything else?

Check Another of Your Medications Against Mountain Ash

Covers the 2,830 medications we’ve checked against Mountain Ash. Pick one to open its full report.

What to actually watch for

What Mountain Ash Itself Has Been Linked To

This is not an interaction — nothing below involves Interferon Beta-1a. It is the side-effect record for Mountain Ash on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Mountain Ash, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

Kidney problems Worth acting on Additional detail
“Orally, consuming large amounts of fresh mountain ash berries can cause serious adverse effects due to its parasorbic acid constituent. These adverse effects include gastroenteritis, vomiting, queasiness, gastric pain, diarrhea, kidney damage, and polymorphic xanthomas (18).”

Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
“Orally, large amounts of fresh mountain ash berries may cause kidney damage, including albuminuria and glycosuria, due to its parasorbic acid constituent (18).”

Mountain Ash · Natural Medicines adverse-effect record, reported in albuminuria.
1 source cited

18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Diarrhea / Vomiting / Nausea Additional detail
“Orally, large amounts of fresh mountain ash berries may cause gastroenteritis, vomiting, queasiness, gastric pain, and diarrhea due to its parasorbic acid constituent (18).”

Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Mountain Ash — expand a row for the licensed statement it rests on. We haven’t matched Interferon Beta-1a to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Interferon Beta-1a.

Special populations

Mountain Ash in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Interferon Beta-1a

This page covers Mountain Ash only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Interferon Beta-1a page lists 57 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Alfalfa (moderate) and Angelica Archangelica (moderate).

By severity: 3 major · 53 moderate · 1 minor.

From our pharmacist’s overview on the Interferon Beta-1a page

“Siberian cocklebur, an herb tied to documented cases of liver failure, is the first name to know for anyone injecting interferon beta-1a (Rebif, Avonex) for multiple sclerosis. Interferon beta-1a can strain the liver on its own, which is why prescribers order routine liver blood tests, and 38 of the 57 supplements on file carry that sa…”

Reviewed by 2 · Jul 18, 2026

Open the Interferon Beta-1a interaction page

One more smart check

Taking Mountain Ash as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mountain Ash, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mountain Ash. Even though Mountain Ash itself has no known interaction with Interferon Beta-1a, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mountain Ash and Interferon Beta-1a Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mountain Ash

Steady interest

#778 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Interferon Beta-1a

Steady interest

#2,320 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mountain Ash reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Mountain Ash and Interferon Beta-1a records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Mountain Ash

What is Mountain Ash?

Sore throat and hoarseness
Digestive upset and constipation
Cough and chest congestion
Mild urinary complaints
Source of vitamin C in folk medicine

Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas. There is very little reliable human research to support any medical use, and raw berries contain compounds that can cause stomach upset, so cooking is important. If you want to try it, talk with your pharmacist or doctor first.

Sorbus aucuparia · Rosaceae · Fruit (berries), and sometimes the flowers and bark · Cooked berries, jam or jelly, juice, syrup, tea, tincture

An interaction check asks whether these two react with each other — it does not ask whether Mountain Ash is a good idea for someone in your situation. Here is what our Mountain Ash record says about it on its own.

Mountain Ash: dosing

There is no established or standardized medicinal dose for mountain ash. It is most often consumed as cooked berries, jam, syrup, or tea rather than as a measured supplement.If you use a commercial product, follow the directions on the label and do not exceed the suggested amount.

From our Mountain Ash monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mountain Ash monograph & all interactions

Medication

About Interferon Beta-1a Intramuscular Injection

What Is Interferon Beta-1a Intramuscular Injection Used For?

Brand names: Rebif, Avonex

Interferon beta-1a intramuscular injection is used to treat adults with various forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control) including:
- clinically isolated syndrome (CIS; nerve symptom episodes that last at least 24 hours),
- relapsing-remitting forms (course of disease where symptoms flare up from time to time), or
- secondary progressive forms (course of disease where relapses occur more often).
Interferon beta-1a is in a class of medications called immunomodulators. It works by decreasing inflammation and preventing nerve damage that may cause symptoms of multiple sclerosis.

Most-Reported Side Effects for Interferon Beta-1a

From FAERS, the FDA’s public side-effect reporting system (192,069 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Multiple sclerosis relapse 15,851 reports

Influenza like illness 13,253 reports

Fatigue 11,554 reports

Fall 10,604 reports

Multiple sclerosis 9,358 reports

See full Interferon Beta-1a Intramuscular Injection drug information

Keep checking

Other Drugs & Mountain Ash

Browse every other medication we’ve checked against Mountain Ash — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

355Moderate

0Minor

2,474No known interaction

355 Moderate 2,474 No interaction

Moderate

355 interactions

Showing 60 of 355 moderate interactions — see all 355 on the Mountain Ash page.

No interaction 2,474 drugs checked — show the list

We also checked Mountain Ash against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,474 medications checked with no known interaction — see the full Mountain Ash list.

See the full Mountain Ash interactions page

See every supplement checked against Interferon Beta-1a, ranked by severity

Evidence & sources

Mountain Ash References

The 1 references that drive our Mountain Ash monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mountain Ash and Interferon Beta-1a Together: Common Questions

Is it safe to take Mountain Ash with Interferon Beta-1a?

We do not list a known interaction between Mountain Ash and Interferon Beta-1a. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Mountain Ash and Interferon Beta-1a combination checked?

Interactions in our licensed database are recorded against drug classes. Interferon Beta-1a is filed under 2 classifications, and Mountain Ash has documented interactions with 1 drug class — none of Interferon Beta-1a's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Mountain Ash interact with any other medications?

Yes. Mountain Ash has 355 documented drug interactions in our database — Interferon Beta-1a is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Interferon Beta-1a interact with any supplements?

Yes. Interferon Beta-1a has documented interactions with 57 supplements in our database — Mountain Ash is not one of them. The Interferon Beta-1a interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Mountain Ash monograph Uses, safety profile, and every drug interaction in one place Interferon Beta-1a Intramuscular Injection drug information The full plain-English guide to this medication Interferon Beta-1a supplement interactions Every supplement checked against Interferon Beta-1a, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Interferon Beta-1a and Mountain Ash?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.