Drug & supplement interaction

Mountain Ash + Tolbutamide

Tolbutamide brand name: Orinase.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Mountain Ash and Tolbutamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Mountain Ash and Tolbutamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolbutamide and Mountain Ash in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mountain Ash safety at a glance

Mountain Ash overall Use caution Cooked berries are generally well tolerated in food amounts, but raw berries can cause stomach upset and evidence for medicinal use is limited.
Pregnancy Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolbutamide and Mountain Ash? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tolbutamide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tolbutamide is filed under 5 classifications — including antidiabetes drugs, cytochrome p450 2c9 (cyp2c9) substrates, photosensitizing drugs. Mountain Ash has documented interactions with 1 drug class — the most serious being nephrotoxic drugs (moderate) — and none of Tolbutamide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Mountain Ash Does Interact With Other Medications

Mountain Ash has 355 moderate known drug interactions in our database — Tolbutamide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 355 No known interaction 2,475 (incl. Tolbutamide)
Taking anything else?

Check Another of Your Medications Against Mountain Ash

Covers the 2,830 medications we’ve checked against Mountain Ash. Pick one to open its full report.

What to actually watch for

What Mountain Ash Itself Has Been Linked To

This is not an interaction — nothing below involves Tolbutamide. It is the side-effect record for Mountain Ash on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Mountain Ash, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    “Orally, consuming large amounts of fresh mountain ash berries can cause serious adverse effects due to its parasorbic acid constituent. These adverse effects include gastroenteritis, vomiting, queasiness, gastric pain, diarrhea, kidney damage, and polymorphic xanthomas (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, large amounts of fresh mountain ash berries may cause kidney damage, including albuminuria and glycosuria, due to its parasorbic acid constituent (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in albuminuria.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  • Diarrhea / Vomiting / Nausea Additional detail

    “Orally, large amounts of fresh mountain ash berries may cause gastroenteritis, vomiting, queasiness, gastric pain, and diarrhea due to its parasorbic acid constituent (18).”

    Mountain Ash · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Mountain Ash — expand a row for the licensed statement it rests on. We haven’t matched Tolbutamide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tolbutamide.

Special populations

Mountain Ash in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When large amounts of fresh berries are ingested. There is insufficient reliable information available about the safety of dried or cooked berries; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tolbutamide

This page covers Mountain Ash only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolbutamide page lists 305 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 255 moderate · 48 minor.

From our pharmacist’s overview on the Tolbutamide page

“People take tolbutamide (Orinase) to lower blood sugar in type 2 diabetes, and diabetes is exactly the condition supplement shelves target, which is why this list runs to 305 ingredients and deserves real caution. Of those, 239 also push glucose around, most often downward, so combining them can drive sugar lower than intended.”

Reviewed by 2 · Jul 18, 2026

Open the Tolbutamide interaction page

One more smart check

Taking Mountain Ash as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mountain Ash, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mountain Ash. Even though Mountain Ash itself has no known interaction with Tolbutamide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mountain Ash and Tolbutamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mountain Ash
Top half

#697 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolbutamide
Steady interest

#2,107 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mountain Ash reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Mountain Ash and Tolbutamide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Mountain Ash

What is Mountain Ash?

Mountain Ash
  • Sore throat and hoarseness
  • Digestive upset and constipation
  • Cough and chest congestion
  • Mild urinary complaints
  • Source of vitamin C in folk medicine

Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas. There is very little reliable human research to support any medical use, and raw berries contain compounds that can cause stomach upset, so cooking is important. If you want to try it, talk with your pharmacist or doctor first.

Sorbus aucuparia · Rosaceae · Fruit (berries), and sometimes the flowers and bark · Cooked berries, jam or jelly, juice, syrup, tea, tincture

An interaction check asks whether these two react with each other — it does not ask whether Mountain Ash is a good idea for someone in your situation. Here is what our Mountain Ash record says about it on its own.

Mountain Ash: dosing

There is no established or standardized medicinal dose for mountain ash. It is most often consumed as cooked berries, jam, syrup, or tea rather than as a measured supplement.If you use a commercial product, follow the directions on the label and do not exceed the suggested amount.

From our Mountain Ash monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mountain Ash monograph & all interactions
Medication

About Tolbutamide

What Is Tolbutamide Used For?

Brand name: Orinase

  • Tolbutamide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Tolbutamide is in a class of medications called sulfonylureas. Tolbutamide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Tolbutamide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

  • Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

See full Tolbutamide drug information
Keep checking

Other Drugs & Mountain Ash

Browse every other medication we’ve checked against Mountain Ash — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
355Moderate
0Minor
2,474No known interaction
355 Moderate 2,474 No interaction
Moderate

355 interactions

Showing 60 of 355 moderate interactions — see all 355 on the Mountain Ash page.

No interaction 2,474 drugs checked — show the list

We also checked Mountain Ash against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,474 medications checked with no known interaction — see the full Mountain Ash list.

See the full Mountain Ash interactions page
See every supplement checked against Tolbutamide, ranked by severity
Evidence & sources

Mountain Ash References

The 1 references that drive our Mountain Ash monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mountain Ash and Tolbutamide Together: Common Questions

Is it safe to take Mountain Ash with Tolbutamide?
We do not list a known interaction between Mountain Ash and Tolbutamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Mountain Ash and Tolbutamide combination checked?
Interactions in our licensed database are recorded against drug classes. Tolbutamide is filed under 5 classifications, and Mountain Ash has documented interactions with 1 drug class — none of Tolbutamide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Mountain Ash interact with any other medications?
Yes. Mountain Ash has 355 documented drug interactions in our database — Tolbutamide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tolbutamide interact with any supplements?
Yes. Tolbutamide has documented interactions with 305 supplements in our database — Mountain Ash is not one of them. The Tolbutamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Mountain Ash monograph Uses, safety profile, and every drug interaction in one place Tolbutamide drug information The full plain-English guide to this medication Tolbutamide supplement interactions Every supplement checked against Tolbutamide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tolbutamide and Mountain Ash?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.