Osha + Atazanavir, Cobicistat
Atazanavir, Cobicistat brand name: Evotaz.
We found no known interaction between Osha and Atazanavir, Cobicistat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Atazanavir, Cobicistat states a food rule worth keeping to.
Osha and Atazanavir, Cobicistat
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Atazanavir, Cobicistat and Osha in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Osha at all — not against Atazanavir, Cobicistat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Osha safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Osha in Pregnancy & Breastfeeding
When used orally. Osha has been used to stimulate menstruation and is reported to have abortifacient activity; contraindicated.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Atazanavir, Cobicistat Products Have a Food Rule — Osha Should Not Break It
At least one FDA label for a product containing Atazanavir, Cobicistat says to take it with food. If you take Osha on an empty stomach out of habit, keep them separate — and take Atazanavir, Cobicistat with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Atazanavir, Cobicistat products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
(2.1) • Recommended dosage: One tablet once daily, taken orally with food in adults and pediatric patients weighing at least 35 kg.
From the Dosage and Administration section of the FDA label we read for Atazanavir, Cobicistat — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Atazanavir, Cobicistat
This page covers Osha only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Atazanavir, Cobicistat page lists 152 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 107 moderate · 42 minor.
From our pharmacist’s overview on the Atazanavir, Cobicistat page
“Evotaz (atazanavir with cobicistat) treats HIV, and its effectiveness depends on steady blood levels, so I read this list of 152 supplements and herbs carefully rather than casually. Only three carry a major rating, but those three deserve your attention first: St.”
Reviewed by 2 · Jul 18, 2026
Taking Osha as Part of a Dietary Supplement Product? Check It for Interactions
We hold 336 real supplement products containing Osha, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Osha. Even though Osha itself has no known interaction with Atazanavir, Cobicistat, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Osha and Atazanavir, Cobicistat Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#463 of 1,452 supplements looked up here in the last 7 days
#381 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Osha reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Osha and Atazanavir, Cobicistat records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Osha
What is Osha?
- Cough and sore throat
- Respiratory infections and colds
- Immune support
- Digestive upset
- Bronchitis and congestion
Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats. Solid human research is lacking, so its benefits remain unproven, and it should be avoided during pregnancy and breastfeeding. Talk to your pharmacist or doctor before trying it.
Ligusticum porteri · Apiaceae · Root · Tea, tincture, capsules, lozenges, chewed raw root
An interaction check asks whether these two react with each other — it does not ask whether Osha is a good idea for someone in your situation. Here is what our Osha record says about it on its own.
Osha: dosing
There is no established standard dose for osha. The right amount depends on the form (tea, tincture, capsule, or lozenge) and the product's strength.If you choose to use osha, follow the directions on the product label and do not exceed them.
From our Osha monograph — the full record covers uses, side effects and every documented interaction.
About Atazanavir and Cobicistat
What Is Atazanavir and Cobicistat Used For?
Brand name: Evotaz
Evotaz (atazanavir/cobicistat) is used to treat HIV-1 infection. It must always be taken together with other antiretroviral medicines — it is not a complete regimen on its own. It is approved for adults and for pediatric patients who weigh at least 35 kg.
In patients who have been on HIV treatment before (treatment-experienced), how well Evotaz works depends on how much resistance to protease inhibitors the virus has already developed. Your prescriber will review this before starting you on Evotaz.
Other Drugs & Osha
Browse every other medication we’ve checked against Osha — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Osha against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Bendamustine ›
- Methotrexate ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Osha list.
Osha References
The 2 references that drive our Osha monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Osha and Atazanavir, Cobicistat Together: Common Questions
Is it safe to take Osha with Atazanavir, Cobicistat?
Should I take Osha and Atazanavir, Cobicistat at the same time of day?
Does Atazanavir, Cobicistat interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Atazanavir, Cobicistat and Osha?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.