Drug & supplement interaction

Pulsed Electromagnetic Field (pemf) Therapy + Pregabalin

Pregabalin brand names: Lyrica, Lyrica CR.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pregabalin and Pulsed Electromagnetic Field (pemf) Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Pulsed Electromagnetic Field (pemf) Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Pulsed Electromagnetic Field (pemf) Therapy at all — not against Pregabalin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Pulsed Electromagnetic Field (pemf) Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pulsed Electromagnetic Field (pemf) Therapy safety at a glance

Pulsed Electromagn... overall Use caution Generally well tolerated for most people, but not appropriate for everyone, especially those with implanted electronic devices.
Pregnancy Avoid Safety during pregnancy has not been established, so it is best avoided unless directed by a doctor.
Breastfeeding Not established There is little research on PEMF use while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pregabalin and Pulsed Electromagnetic Field (pemf) Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Pulsed Electromagnetic Field (pemf) Therapy while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Raised blood pressure Worth acting on Additional detail

    Pulsed Electromagnetic Field (pemf) Therapy

    “In one study, two patients given PEMF treatment had orthostatic hypertension which resolved upon treatment discontinuation.”

    Pulsed Electromagnetic Field (pemf) Therapy · Natural Medicines adverse-effect record, reported in hypertension.

    1 source cited
    1. 109144. Sutbeyaz ST, Sezer N, Koseoglu F, Kibar S. Low-frequency pulsed electromagnetic field therapy in fibromyalgia: a randomized, double-blind, sham-controlled clinical study. Clin J Pain. 2009;25(8):722-8. PubMed

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

Effects for Pregabalin come from the ADVERSE REACTIONS section of its FDA label; effects for Pulsed Electromagnetic Field (pemf) Therapy come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Pregabalin Is Prescribed For, and What Pulsed Electromagnetic Field (pemf) Therapy Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Pregabalin is a prescription medicine with approved uses on its FDA label. Pulsed Electromagnetic Field (pemf) Therapy is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Pregabalin is prescribed for: Pregabalin is used to manage several types of nerve pain, including neuropathic pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) and postherpetic neuralgia (lingering nerve pain after shingles). It is also used to treat fibromyalgia and neuropathic pain associated with spinal cord injury. Lyrica (capsule and oral solution), pregabalin capsules, and pregabalin oral solution are also approved as add-on therapy for partial-onset seizures — Lyrica for patients 1 month and older, and pregabalin capsules for patients 17 years and older. Lyrica CR and pregabalin extended-release tablets are approved only for diabetic peripheral neuropathy pain and postherpetic neuralgia — their effectiveness for fibromyalgia or as seizure add-on therapy has not been established.

Pulsed Electromagnetic Field (pemf) Therapy has been studied for:

  • Fibromyalgia studied, not established Pulsed Electromagnetic Field (pemf) Therapy has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Pulsed Electromagnetic Field (pemf) Therapy for fibromyalgia

    It is unclear if PEMF therapy is beneficial for fibromyalgia.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Pregabalin on your own; if you are taking Pulsed Electromagnetic Field (pemf) Therapy for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Pulsed Electromagnetic Field (pemf) Therapy or Pregabalin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Pulsed Electromagnetic Field (pemf) Therapy or Pregabalin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Pregabalin

This page covers Pulsed Electromagnetic Field (pemf) Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pregabalin page lists 95 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 73 moderate · 15 minor.

From our pharmacist’s overview on the Pregabalin page

“Pregabalin (Lyrica) calms overactive nerves, which is how it eases nerve pain, seizures, and anxiety, and that calming action stacks with almost everything on this list. Of the 95 supplements and herbs, the large majority add their own sedation on top of pregabalin's, and a few can tip that into genuine danger, with deep sedation and s…”

Reviewed by 2 · Jul 18, 2026

Open the Pregabalin interaction page

How much people look this up

Where Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pulsed Electromagnetic Field (pemf) Therapy
Steady interest

#1,371 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pregabalin
Top 5%

#40 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pulsed Electromagnetic Field (pemf) Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Pulsed Electromagnetic Field (pemf) Therapy

What is Pulsed Electromagnetic Field (pemf) Therapy?

  • Bone healing (fractures and non-unions)
  • Osteoarthritis and joint pain
  • General pain and inflammation
  • Muscle recovery and stiffness
  • Wound healing
  • Sleep and relaxation

PEMF therapy uses pulsing electromagnetic fields from a device to try to ease pain and support tissue or bone healing. The strongest evidence is for certain bone-healing uses, where it is FDA-cleared; for most other claims the evidence is limited or mixed. It is generally well tolerated, but people with implanted electronic devices and those who are pregnant should avoid it unless a doctor approves.

Not applicable (a device-based therapy, not an herb or supplement) · Mats, pads, rings, handheld wands, and full-body devices that deliver electromagnetic pulses

An interaction check asks whether these two react with each other — it does not ask whether Pulsed Electromagnetic Field (pemf) Therapy is a good idea for someone in your situation. Here is what our Pulsed Electromagnetic Field (pemf) Therapy record says about it on its own.

Pulsed Electromagnetic Field (pemf) Therapy: dosing

There is no single standard dose for PEMF therapy. Settings such as frequency, intensity, session length, and how often to use the device vary widely between products and conditions.For medical-grade devices used for bone healing, the doctor or device maker provides a specific treatment schedule.

From our Pulsed Electromagnetic Field (pemf) Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pulsed Electromagnetic Field (pemf) Therapy monograph & all interactions
Medication

About Pregabalin

What Is Pregabalin Used For?

Brand names: Lyrica, Lyrica CR

Pregabalin is used to manage several types of nerve pain, including neuropathic pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) and postherpetic neuralgia (lingering nerve pain after shingles). It is also used to treat fibromyalgia and neuropathic pain associated with spinal cord injury.

Lyrica (capsule and oral solution), pregabalin capsules, and pregabalin oral solution are also approved as add-on therapy for partial-onset seizures — Lyrica for patients 1 month and older, and pregabalin capsules for patients 17 years and older. Lyrica CR and pregabalin extended-release tablets are approved only for diabetic peripheral neuropathy pain and postherpetic neuralgia — their effectiveness for fibromyalgia or as seizure add-on therapy has not been established.

Most-Reported Side Effects for Pregabalin

From FAERS, the FDA’s public side-effect reporting system (270,557 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 15,629 reports
Dizziness 14,844 reports
Nausea 14,507 reports
Headache 13,067 reports
Malaise 12,884 reports
See full Pregabalin drug information
Keep checking

Other Drugs & Pulsed Electromagnetic Field (pemf) Therapy

Browse every other medication we’ve checked against Pulsed Electromagnetic Field (pemf) Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Pulsed Electromagnetic Field (pemf) Therapy References

The 1 references that drive our Pulsed Electromagnetic Field (pemf) Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sutbeyaz ST, Sezer N, Koseoglu F, Kibar S. Low-frequency pulsed electromagnetic field therapy in fibromyalgia: a randomized, double-blind, sham-controlled clinical study. Clin J Pain. 2009;25(8):722-8. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Pulsed Electromagnetic Field (pemf) Therapy While Taking Pregabalin: Common Questions

Is it safe to have Pulsed Electromagnetic Field (pemf) Therapy while taking Pregabalin?
We do not list a known interaction between Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Pulsed Electromagnetic Field (pemf) Therapy and Pregabalin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Pulsed Electromagnetic Field (pemf) Therapy in each. That is a conversation for your prescriber, especially if Pregabalin is being adjusted to a target.
Does Pregabalin interact with any supplements?
Yes. Pregabalin has documented interactions with 95 supplements in our database — Pulsed Electromagnetic Field (pemf) Therapy is not one of them. The Pregabalin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Pregabalin and Pulsed Electromagnetic Field (pemf) Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.