Queen's Delight + Medroxyprogesterone
Medroxyprogesterone brand names: Provera, Amen, Depo-Provera, Depo-subQ Provera 104.
We found no known interaction between Queen's Delight and Medroxyprogesterone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Queen's Delight and Medroxyprogesterone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Medroxyprogesterone and Queen's Delight in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Queen's Delight at all — not against Medroxyprogesterone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Queen's Delight safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Queen's Delight in Pregnancy & Breastfeeding
When the dried root preparations are used orally. ...when the dried or fresh root is used topically; avoid using.
When the fresh root preparations are used orally.
When the dried or fresh root are used topically.
When used orally; contraindicated.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Questions About Queen's Delight or Medroxyprogesterone
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Queen's Delight or Medroxyprogesterone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Medroxyprogesterone
This page covers Queen's Delight only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Medroxyprogesterone page lists 139 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 95 moderate · 41 minor.
From our pharmacist’s overview on the Medroxyprogesterone page
“Medroxyprogesterone (Provera, Depo-Provera) only works if its blood level holds steady, and 121 of the 139 supplements and herbs on file can shift that level through a single liver enzyme, CYP3A4. That makes this a list to respect, with three entries rated major.”
Reviewed by 2 · Jul 18, 2026
Taking Queen's Delight as Part of a Dietary Supplement Product? Check It for Interactions
We hold 14 real supplement products containing Queen's Delight, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Queen's Delight. Even though Queen's Delight itself has no known interaction with Medroxyprogesterone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Queen's Delight and Medroxyprogesterone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#876 of 1,452 supplements looked up here in the last 7 days
#1,181 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Queen's Delight reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Queen's Delight and Medroxyprogesterone records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Queen's Delight
What is Queen's Delight?
- Skin conditions and 'blood purifying'
- Chronic skin eruptions (eczema, psoriasis)
- Syphilis and other infections (historical use)
- Sore throat and respiratory complaints
- Constipation (as a laxative)
Queen's Delight (Stillingia sylvatica) is a traditional North American herb once used as a 'blood purifier' and for skin and throat problems. There is very little modern scientific evidence to support these uses, and the plant contains irritating compounds that can cause significant side effects. Talk with a pharmacist or doctor before trying it.
Stillingia sylvatica · Euphorbiaceae · Root and dried root (sometimes the root resin/oil) · Dried root, tincture, fluid extract, capsules, and as part of traditional herbal blends
An interaction check asks whether these two react with each other — it does not ask whether Queen's Delight is a good idea for someone in your situation. Here is what our Queen's Delight record says about it on its own.
Queen's Delight: dosing
There is no well-established, standardized dose for Queen's Delight. Traditional herbalists used small amounts of the dried root, tincture, or fluid extract, but these doses were not tested in modern clinical studies.If you choose to use a product, follow the directions on the label and do not exceed them. Because the herb can be irritating, starting low and using it only briefly is wise.
From our Queen's Delight monograph — the full record covers uses, side effects and every documented interaction.
About Medroxyprogesterone
What Is Medroxyprogesterone Used For?
Brand names: Provera, Amen, Depo-Provera, Depo-subQ Provera 104
Medroxyprogesterone is used for different conditions depending on the product form. The injectable forms — including Depo-Provera and intramuscular medroxyprogesterone acetate injectable suspension — are used to prevent pregnancy. Depo-subQ Provera 104 (the subcutaneous injection) is also approved to manage pain associated with endometriosis.
The oral tablets — sold under the brand Provera and as generic medroxyprogesterone acetate tablets — treat secondary amenorrhea (periods that have stopped) and abnormal uterine bleeding caused by hormonal imbalance. The tablets are also used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking daily conjugated estrogens.
Most-Reported Side Effects for Medroxyprogesterone
From FAERS, the FDA’s public side-effect reporting system (60,501 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Queen's Delight
Browse every other medication we’ve checked against Queen's Delight — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Queen's Delight against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Queen's Delight list.
Queen's Delight References
The 4 references that drive our Queen's Delight monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Queen's Delight and Medroxyprogesterone Together: Common Questions
Is it safe to take Queen's Delight with Medroxyprogesterone?
Do Queen's Delight and Medroxyprogesterone have any of the same side effects?
Does Medroxyprogesterone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Medroxyprogesterone and Queen's Delight?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.