Drug & supplement interaction

Quince + Clomiphene

Clomiphene brand names: Serophene, Clomid.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Quince and Clomiphene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Quince and Clomiphene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clomiphene and Quince in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quince at all — not against Clomiphene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quince safety at a glance

Quince overall Use caution Quince as a food is generally well tolerated, but concentrated supplements are not well studied.
Pregnancy Use caution Quince as food is likely fine, but concentrated extracts or seed products lack safety data, so use caution.
Breastfeeding Use caution There is not enough reliable information on quince supplements during breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clomiphene and Quince? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Clomiphene’s Own FDA Label Lists

This is not an interaction — none of it involves Quince. These are the most notable effects listed in the ADVERSE REACTIONS section of Clomiphene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Loss of vision Worth acting on
  • A change in thyroid levels Worth acting on
  • Hearing loss Worth acting on
  • Blood clots Worth acting on
  • Hallucinations Worth acting on
  • Pancreatitis Worth acting on
  • Fainting Worth acting on
  • An irregular heartbeat Worth acting on
  • A severe skin reaction Worth acting on
  • Seizures Worth acting on

Showing the 10 most notable of 45 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Clomiphene. Read the label on DailyMed › Quince’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Quince side to compare — that is a limit of the record, not a statement that Quince has no side effects.

Everything else you take

See Every Supplement That Interacts With Clomiphene

This page covers Quince only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clomiphene page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Clomiphene page

“Clomiphene (Clomid, Serophene) is taken as a short, precisely timed course to trigger ovulation, so anything that weakens a dose can cost someone trying to conceive a whole cycle. That is why the 17 supplements listed here deserve genuine care, since every one of them can change how much of the pill the gut actually absorbs.”

Reviewed by 2 · Jul 18, 2026

Open the Clomiphene interaction page

One more smart check

Taking Quince as Part of a Dietary Supplement Product? Check It for Interactions

We hold 25 real supplement products containing Quince, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quince. Even though Quince itself has no known interaction with Clomiphene, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Quince and Clomiphene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quince
Steady interest

#952 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clomiphene
Top half

#1,030 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Quince and Clomiphene records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quince

What is Quince?

  • Digestive upset and diarrhea
  • Acid reflux and heartburn
  • Sore throat and cough
  • Skin soothing and wound care
  • Nausea

Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.

Cydonia oblonga · Rosaceae · Fruit, seeds, and leaves · Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Quince is a good idea for someone in your situation. Here is what our Quince record says about it on its own.

Quince: dosing

There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds.

From our Quince monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quince monograph & all interactions
Medication

About Clomiphene

What Is Clomiphene Used For?

Brand names: Serophene, Clomid

Clomiphene tablets are indicated for women who are not ovulating normally and want to become pregnant. It is most likely to help women with polycystic ovary syndrome (PCOS), amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea (absent periods of unknown cause).

Before starting treatment, other barriers to pregnancy — such as thyroid disorders, adrenal disorders, high prolactin levels, or male factor infertility — must be ruled out or treated. Clomiphene is not recommended for use in combination with other ovulation-inducing drugs or for IVF programs, and it is not approved for treating male infertility.

See full Clomiphene drug information
Keep checking

Other Drugs & Quince

Browse every other medication we’ve checked against Quince — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Sources

Sources & How We Checked

We checked Quince against Clomiphene in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Quince and Clomiphene Together: Common Questions

Is it safe to take Quince with Clomiphene?
We do not list a known interaction between Quince and Clomiphene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Clomiphene interact with any supplements?
Yes. Clomiphene has documented interactions with 17 supplements in our database — Quince is not one of them. The Clomiphene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Clomiphene and Quince?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.