Drug & supplement interaction

Rupturewort + Aminophylline, Amobarbital, Ephedrine

Aminophylline, Amobarbital, Ephedrine brand name: Amesec.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rupturewort and Aminophylline, Amobarbital, Ephedrine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Rupturewort and Aminophylline, Amobarbital, Ephedrine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aminophylline, Amobarbital, Ephedrine and Rupturewort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rupturewort safety at a glance

Rupturewort overall Use caution Limited safety data exist, so use carefully and under professional guidance.
Pregnancy Avoid Not enough safety information; traditional diuretic use makes it best avoided in pregnancy.
Breastfeeding Avoid No reliable safety data, so it is best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aminophylline, Amobarbital, Ephedrine and Rupturewort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Aminophylline, Amobarbital, Ephedrine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Aminophylline, Amobarbital, Ephedrine is filed under 8 classifications — including ephedrine, methylxanthines, barbiturates. Rupturewort has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Aminophylline, Amobarbital, Ephedrine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Rupturewort Does Interact With Other Medications

Rupturewort has 1 moderate known drug interaction in our database — Aminophylline, Amobarbital, Ephedrine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Rupturewort

Covers the 2,830 medications we’ve checked against Rupturewort. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Aminophylline, Amobarbital, Ephedrine

This page covers Rupturewort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aminophylline, Amobarbital, Ephedrine page lists 151 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Black Tea (major) and Caffeine (major).

By severity: 21 major · 108 moderate · 22 minor.

From our pharmacist’s overview on the Aminophylline, Amobarbital, Ephedrine page

“Amesec is an unusual mix, a sedative barbiturate (amobarbital) plus the stimulant ephedrine and the asthma drug aminophylline, so its interaction list pulls hard in both directions and deserves real care, with 21 of the 151 ingredients rated major. The most everyday hazard is caffeine.”

Reviewed by 2 · Jul 18, 2026

Open the Aminophylline, Amobarbital, Ephedrine interaction page

One more smart check

Taking Rupturewort as Part of a Dietary Supplement Product? Check It for Interactions

We hold 19 real supplement products containing Rupturewort, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rupturewort. Even though Rupturewort itself has no known interaction with Aminophylline, Amobarbital, Ephedrine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rupturewort and Aminophylline, Amobarbital, Ephedrine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rupturewort
Steady interest

#807 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aminophylline, Amobarbital, Ephedrine
Top 5%

#99 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rupturewort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Rupturewort and Aminophylline, Amobarbital, Ephedrine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rupturewort

What is Rupturewort?

  • Urinary tract complaints
  • Mild fluid retention (as a diuretic)
  • Kidney and bladder support
  • Wound healing and inflammation (topical, traditional)
  • Spasms or cramping (traditional)

Rupturewort is a traditional European herb mainly used as a mild diuretic and for urinary complaints. Solid human research is very limited, so its true benefits and long-term safety are not well established. Talk to a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Herniaria glabra · Caryophyllaceae · Aerial parts (the above-ground flowering herb) · Tea, dried herb, tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Rupturewort is a good idea for someone in your situation. Here is what our Rupturewort record says about it on its own.

Rupturewort: dosing

There is no well-established or standardized dose for rupturewort. Traditional use involves brewing the dried herb as a tea, but reliable dosing guidance from clinical research does not exist.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Rupturewort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rupturewort monograph & all interactions
Keep checking

Other Drugs & Rupturewort

Browse every other medication we’ve checked against Rupturewort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list
Evidence & sources

Rupturewort References

The 1 references that drive our Rupturewort monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hakim EM, Sivak KV, Kaukhova IE. Evaluation of the diuretic effect of crude ethanol and saponin-rich extracts of Herniaria glabra L. in rats. J Ethnopharmacol. 2021 Jun 12;273:113942. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rupturewort and Aminophylline, Amobarbital, Ephedrine Together: Common Questions

Is it safe to take Rupturewort with Aminophylline, Amobarbital, Ephedrine?
We do not list a known interaction between Rupturewort and Aminophylline, Amobarbital, Ephedrine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Rupturewort and Aminophylline, Amobarbital, Ephedrine combination checked?
Interactions in our licensed database are recorded against drug classes. Aminophylline, Amobarbital, Ephedrine is filed under 8 classifications, and Rupturewort has documented interactions with 1 drug class — none of Aminophylline, Amobarbital, Ephedrine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Rupturewort interact with any other medications?
Yes. Rupturewort has 1 documented drug interaction in our database — Aminophylline, Amobarbital, Ephedrine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Aminophylline, Amobarbital, Ephedrine interact with any supplements?
Yes. Aminophylline, Amobarbital, Ephedrine has documented interactions with 151 supplements in our database — Rupturewort is not one of them. The Aminophylline, Amobarbital, Ephedrine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Aminophylline, Amobarbital, Ephedrine and Rupturewort?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.