Medication interaction hub

What Supplements Interact with Aminophylline, Amobarbital, Ephedrine?

Aminophylline, Amobarbital, Ephedrine brand name: Amesec. Every interaction below applies to the brands too.

151 Interactions 21 Major 108 Moderate 22 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aminophylline, Amobarbital, Ephedrine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aminophylline, Amobarbital, Ephedrine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Amesec is an unusual mix, a sedative barbiturate (amobarbital) plus the stimulant ephedrine and the asthma drug aminophylline, so its interaction list pulls hard in both directions and deserves real care, with 21 of the 151 ingredients rated major. The most everyday hazard is caffeine. Coffee, green tea, guarana and similar products can push ephedrine toward dangerous blood pressure spikes, even heart attack or stroke. On the sedative side, alcohol and kava deepen the barbiturate's drowsiness, and at worst can slow breathing.

Most of the list falls into those two camps: 78 ingredients add sedation and 44 add stimulation, while 108 entries overall are moderate and 22 minor. Activated charcoal is different, since it can soak up the medication itself and blunt the dose, so space it well apart from your pills. With a combination this touchy, run every supplement, even a caffeinated one, past your pharmacist first.

— , Clinical Pharmacist · July 18, 2026

Major 21 Moderate 108 Minor 22 No known interaction 1,301

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aminophylline, Amobarbital, Ephedrine: Top Interactions at a Glance

The Aminophylline, Amobarbital, Ephedrine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 151 interacting ingredients — plus 1,301 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Aminophylline, Amobarbital, Ephedrine Combinations Today

The Aminophylline, Amobarbital, Ephedrine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Major Likelihood Probable Coffee + Aminophylline, Amobarbital, Ephedrinei

Theoretically, concomitant use might increase the risk of stimulant adverse effects.

Read the full interaction Major Likelihood Probable Green Tea + Aminophylline, Amobarbital, Ephedrinei

Theoretically, concomitant use might increase the risk for stimulant adverse effects.

Read the full interaction Major Likelihood Probable Caffeine + Aminophylline, Amobarbital, Ephedrinei

Theoretically, concomitant use might increase the risk for stimulant adverse effects.

Read the full interaction Moderate Likelihood Possible Glutamine + Aminophylline, Amobarbital, Ephedrinei

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Read the full interaction Minor Likelihood Possible Adenosine + Aminophylline, Amobarbital, Ephedrinei

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.

Read the full interaction Major Likelihood Probable Black Tea + Aminophylline, Amobarbital, Ephedrinei

Theoretically, concomitant use might increase the risk for simulant adverse effects.

Read the full interaction
The complete list

Every Supplement Checked Against Aminophylline, Amobarbital, Ephedrine

All 1,452 ingredients in our database, ranked by severity — 151 with a Aminophylline, Amobarbital, Ephedrine interaction on file and 1,301 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aminophylline, Amobarbital, Ephedrine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Coffee with Aminophylline, Amobarbital, Ephedrine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use might increase the risk of stimulant adverse effects.

Full Coffee + Aminophylline, Amobarbital, Ephedrine answer

Can you take Green Tea with Aminophylline, Amobarbital, Ephedrine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use might increase the risk for stimulant adverse effects.

Full Green Tea + Aminophylline, Amobarbital, Ephedrine answer

Can you take Caffeine with Aminophylline, Amobarbital, Ephedrine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use might increase the risk for stimulant adverse effects.

Full Caffeine + Aminophylline, Amobarbital, Ephedrine answer

Can you take Glutamine with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Full Glutamine + Aminophylline, Amobarbital, Ephedrine answer

Can you take Adenosine with Aminophylline, Amobarbital, Ephedrine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.

Full Adenosine + Aminophylline, Amobarbital, Ephedrine answer

Can you take Cocoa with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase stimulant adverse effects.

Full Cocoa + Aminophylline, Amobarbital, Ephedrine answer

Can you take Coffee Charcoal with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Aminophylline, Amobarbital, Ephedrine answer

Can you take Cola Nut with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase stimulant adverse effects.

Full Cola Nut + Aminophylline, Amobarbital, Ephedrine answer

Can you take European Mandrake with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Aminophylline, Amobarbital, Ephedrine answer

Can you take Fever Bark with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fever bark might increase or decrease the effects of stimulant drugs.

Full Fever Bark + Aminophylline, Amobarbital, Ephedrine answer

Can you take Glucomannan with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Aminophylline, Amobarbital, Ephedrine answer

Can you take Indian Snakeroot with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Indian snakeroot with ephedrine might alter the effects and side effects of ephedrine.

Full Indian Snakeroot + Aminophylline, Amobarbital, Ephedrine answer

Can you take Lithium with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lithium supplements with methylxanthines might decrease lithium levels.

Full Lithium + Aminophylline, Amobarbital, Ephedrine answer

Can you take Psilocybin with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of psilocybin with stimulant drugs might increase stimulant adverse effects.

Full Psilocybin + Aminophylline, Amobarbital, Ephedrine answer

Can you take Yerba Mansa with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might cause additive or prolonged sedative effects.

Full Yerba Mansa + Aminophylline, Amobarbital, Ephedrine answer

Can you take 1,3-dmaa with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,3-DMAA is thought to have stimulant effects.

Full 1,3-dmaa + Aminophylline, Amobarbital, Ephedrine answer

Can you take 1,3-dmba with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining 1,3-DMBA with other stimulant drugs might increase the risk of cardiovascular toxicity.

Full 1,3-dmba + Aminophylline, Amobarbital, Ephedrine answer

Can you take 1,4-dmaa with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,4-DMAA is thought to have stimulant and vasoconstrictive effects, which have been demonstrated in animal studies.

Full 1,4-dmaa + Aminophylline, Amobarbital, Ephedrine answer

Can you take 5-htp with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.

Full 5-htp + Aminophylline, Amobarbital, Ephedrine answer

Can you take Acacia Rigidula with Aminophylline, Amobarbital, Ephedrine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Acacia rigidula with stimulant drugs might increase the risk of adverse cardiovascular effects.

Full Acacia Rigidula + Aminophylline, Amobarbital, Ephedrine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aminophylline, Amobarbital, Ephedrine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aminophylline, Amobarbital, Ephedrine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aminophylline, Amobarbital, Ephedrine sits in 8 interaction categories. Open any one to see what the group means:

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Stimulant Drugs 44 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

44 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Anticonvulsants 15 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

15 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Ephedrine 14 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

14 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Barbiturates 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Methylxanthines 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aminophylline, Amobarbital, Ephedrine through this category.

Alpha-Adrenergic Agonists 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Aminophylline, Amobarbital, Ephedrine through this category.

Related: does Aminophylline, Amobarbital, Ephedrine deplete any nutrients?

Aminophylline, Amobarbital, Ephedrine has 2 reported nutrient associations in the research literature — see the Aminophylline, Amobarbital, Ephedrine nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aminophylline, Amobarbital, Ephedrine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aminophylline, Amobarbital, Ephedrine.

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Products that contain Aminophylline, Amobarbital, Ephedrine-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Aminophylline, Amobarbital, Ephedrine.

Marine Collagen by Number One Nutrition contains Black Tea LHC+ by Number One Nutrition contains Black Tea Energy Complex by Nutricost contains Black Tea Senolytic Complex by SuperSmart contains Black Tea
Pharmacist Counseling Corner

Aminophylline, Amobarbital, Ephedrine & Supplements: Common Questions

What supplements interact with Aminophylline, Amobarbital, Ephedrine?
In our interaction database, 151 supplement and herbal ingredients have an interaction with Aminophylline, Amobarbital, Ephedrine on file — 21 rated major, 108 moderate, and 22 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Beer, Wine, 1,4-butanediol.
Which Aminophylline, Amobarbital, Ephedrine supplement interactions are the most serious?
The 21 major-rated combinations — led by Beer, Wine, 1,4-butanediol, Activated Charcoal and Black Tea — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Aminophylline, Amobarbital, Ephedrine?
That depends entirely on which supplement. The honest answer for Aminophylline, Amobarbital, Ephedrine is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Amesec have the same supplement interactions as Aminophylline, Amobarbital, Ephedrine?
Yes — Amesec all contain Aminophylline, Amobarbital, Ephedrine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aminophylline, Amobarbital, Ephedrine deplete any vitamins or nutrients?
It might — Aminophylline, Amobarbital, Ephedrine has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aminophylline, Amobarbital, Ephedrine nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aminophylline, Amobarbital, Ephedrine and my other medications?
This page covers Aminophylline, Amobarbital, Ephedrine against supplements and herbal ingredients. Checking Aminophylline, Amobarbital, Ephedrine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.