Drug & supplement interaction

Sessile Oak + Trimipramine

Trimipramine brand names: Surmontil, Trimip, Rhotrimine, Tripramine, Trimp.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Sessile Oak and Trimipramine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Sessile Oak and Trimipramine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Trimipramine and Sessile Oak in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sessile Oak at all — not against Trimipramine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sessile Oak safety at a glance

Sessile Oak overall Use caution Generally used short term; high tannin content can irritate the stomach and should not be used on large or broken skin areas for long.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Trimipramine and Sessile Oak? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Trimipramine’s Own FDA Label Lists

This is not an interaction — none of it involves Sessile Oak. These are the most notable effects listed in the ADVERSE REACTIONS section of Trimipramine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Dependence or withdrawal symptoms Worth acting on
  • A bowel blockage Worth acting on
  • Trouble passing urine Worth acting on
  • Unsteadiness Worth acting on
  • A heart attack Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on

Showing the 10 most notable of 49 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Trimipramine. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,449 voluntary FDA FAERS reports for Trimipramine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Sessile Oak’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Sessile Oak side to compare — that is a limit of the record, not a statement that Sessile Oak has no side effects.

Everything else you take

See Every Supplement That Interacts With Trimipramine

This page covers Sessile Oak only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Trimipramine page lists 139 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 9 major · 100 moderate · 30 minor.

From our pharmacist’s overview on the Trimipramine page

“If you take trimipramine (Surmontil), a tricyclic antidepressant, read this list carefully. Nine of the 139 supplements and herbs on file are rated major, and most touch the heart: several, grapefruit among them, can stretch the QT interval, the heart's electrical reset time, and raise the risk of a dangerous rhythm.”

Reviewed by 2 · Jul 18, 2026

Open the Trimipramine interaction page

How much people look this up

Where Sessile Oak and Trimipramine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sessile Oak
Steady interest

#1,257 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Trimipramine
Steady interest

#1,960 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Sessile Oak is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sessile Oak reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Sessile Oak and Trimipramine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sessile Oak

What is Sessile Oak?

  • Diarrhea
  • Sore throat and mouth inflammation
  • Minor skin irritation and weeping skin conditions
  • Hemorrhoids (sitz baths)
  • Mild wounds and inflammation (topical wash)

Sessile oak is a European oak tree whose tannin-rich bark has a long history in traditional medicine, mainly as an astringent for diarrhea, sore throat, and skin problems. Human evidence is very limited, and it is best used short term and externally; talk to a pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding due to lack of safety data.

Quercus petraea · Fagaceae · Bark, and sometimes leaves and acorns · Dried bark, tea (decoction), liquid extract, and topical washes or baths

An interaction check asks whether these two react with each other — it does not ask whether Sessile Oak is a good idea for someone in your situation. Here is what our Sessile Oak record says about it on its own.

Sessile Oak: dosing

There is no single standardized dose of sessile oak that has been established by strong clinical research. Traditional uses include drinking a bark tea, gargling with a cooled bark tea, applying a wash to the skin, or adding a bark preparation to a bath.The safest approach is to follow the directions on the product label and to use it only for a short period.

From our Sessile Oak monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sessile Oak monograph & all interactions
Medication

About Trimipramine

What Is Trimipramine Used For?

Brand names: Surmontil, Trimip, Rhotrimine, Tripramine, Trimp

Trimipramine capsules are indicated for the relief of symptoms of depression. Endogenous depression — depression that arises from within, rather than from an obvious outside cause — is more likely to respond to treatment than other types.

In clinical studies, trimipramine worked as well as imipramine in hospitalized patients with depression, and was comparable to amitriptyline in less severely depressed outpatients.

See full Trimipramine drug information
Keep checking

Other Drugs & Sessile Oak

Browse every other medication we’ve checked against Sessile Oak — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Sessile Oak against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Sessile Oak list.

See the full Sessile Oak interactions page
See every supplement checked against Trimipramine, ranked by severity
Evidence & sources

Sessile Oak References

The 1 sources that drive our Sessile Oak monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Sessile Oak is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Sessile Oak and Trimipramine Together: Common Questions

Is it safe to take Sessile Oak with Trimipramine?
We do not list a known interaction between Sessile Oak and Trimipramine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Trimipramine interact with any supplements?
Yes. Trimipramine has documented interactions with 139 supplements in our database — Sessile Oak is not one of them. The Trimipramine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Sessile Oak monograph Uses, safety profile, and every drug interaction in one place Trimipramine drug information The full plain-English guide to this medication Trimipramine supplement interactions Every supplement checked against Trimipramine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Trimipramine and Sessile Oak?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.