Watercress + Cefaclor
Cefaclor brand names: Ceclor CD, Ceclor.
We found no known interaction between Watercress and Cefaclor in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Cefaclor states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Watercress and Cefaclor
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Cefaclor and Watercress in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Watercress safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Cefaclor
Interactions in our licensed database are recorded against drug classes, not just single drug names. Cefaclor is filed under 6 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, antibiotic drugs. Watercress has documented interactions with 3 drug classes — the most serious being chlorzoxazone (parafon forte, paraflex) (moderate), lithium (moderate) and warfarin (coumadin) (moderate) — and none of Cefaclor’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Watercress Does Interact With Other Medications
Watercress has 6 moderate known drug interactions in our database — Cefaclor isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Watercress
We haven’t checked that one against Watercress yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Watercress. Pick one to open its full report.
Watercress in Pregnancy & Breastfeeding
When used in medicinal amounts. Watercress might stimulate menstruation or have abortifacient effects.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Cefaclor Products Have a Food Rule — Watercress Should Not Break It
At least one FDA label for a product containing Cefaclor says to take it with food. If you take Watercress on an empty stomach out of habit, keep them separate — and take Cefaclor with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Cefaclor products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
DOSAGE AND ADMINISTRATION The absorption of cefaclor extended-release tablets is enhanced when it is administered with food.
From the Dosage and Administration section of the FDA label we read for Cefaclor — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Cefaclor
This page covers Watercress only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cefaclor page lists 60 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).
By severity: 3 major · 46 moderate · 11 minor.
From our pharmacist’s overview on the Cefaclor page
“The entries worth understanding before any others on this cefaclor (Ceclor) page are the kidney risks and charcoal. Cefaclor is a cephalosporin antibiotic, typically a short course for ear, sinus, throat, or skin infections, and two herbs here, Siberian cocklebur and asarabacca, can damage the kidneys on their own, so pairing either wi…”
Reviewed by 2 · Jul 18, 2026
Taking Watercress as Part of a Dietary Supplement Product? Check It for Interactions
We hold 820 real supplement products containing Watercress, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Watercress. Even though Watercress itself has no known interaction with Cefaclor, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Watercress and Cefaclor Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#276 of 1,452 supplements looked up here in the last 7 days
#225 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Watercress reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Watercress and Cefaclor records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Watercress
What is Watercress?
- Source of vitamins and minerals
- Antioxidant support
- General nutrition
- Traditional cough and congestion remedy
- Skin and detox tonics
Watercress is a nutrient-rich leafy green that provides vitamins A, C, and K plus minerals and antioxidant plant compounds. Eaten as a food it is generally safe and healthy for most people, but strong human evidence for concentrated supplement health claims is limited. Talk to your pharmacist or doctor before using high-dose extracts, especially if you are pregnant, breastfeeding, or have a medical condition.
Nasturtium officinale · Brassicaceae · Leaves and stems (above-ground parts) · Fresh leafy green, salad, juice, extract capsules, dried herb
An interaction check asks whether these two react with each other — it does not ask whether Watercress is a good idea for someone in your situation. Here is what our Watercress record says about it on its own.
Watercress: dosing
There is no official or standardized dose for watercress as a supplement. As a food, it is simply eaten in salads or cooked dishes in the amount you enjoy.For capsules, powders, or extracts, follow the directions on the product label, since strength varies between products. More is not always better, and concentrated extracts have not been well studied for safety.
From our Watercress monograph — the full record covers uses, side effects and every documented interaction.
About Cefaclor
What Is Cefaclor Used For?
Brand names: Ceclor CD, Ceclor
Cefaclor treats a range of bacterial infections. The capsule and oral suspension forms are used for ear infections (otitis media), lower respiratory tract infections including pneumonia, strep throat and tonsillitis, urinary tract infections (including kidney infections and bladder infections), and skin and skin structure infections.
The extended-release tablet form of Cefaclor is approved for a narrower set of uses: acute bacterial flare-ups of chronic bronchitis, strep throat and tonsillitis, and uncomplicated skin infections. Not all infections approved for the capsule or suspension are approved for the extended-release tablet — your prescriber will choose the right form for your infection.
Most-Reported Side Effects for Cefaclor
From FAERS, the FDA’s public side-effect reporting system (1,535 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Watercress
Browse every other medication we’ve checked against Watercress — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
6 interactions
No interaction 2,823 drugs checked — show the list
We also checked Watercress against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Ivermectin ›
- Abemaciclib ›
- Testosterone ›
- Losartan Potassium ›
- Sertraline ›
- Acetaminophen ›
- Rosuvastatin ›
- Aspirin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Rivaroxaban ›
- Isotretinoin ›
- Tirzepatide ›
- Ibuprofen ›
- Levothyroxine, Liothyronine ›
- Amlodipine Besylate ›
- Docusate ›
- Methamphetamine ›
- Prednisone ›
- Metformin ›
- Amitriptyline ›
- Tadalafil ›
- Semaglutide ›
- Lisdexamfetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Amphetamine ›
- Sumatriptan ›
- Propranolol ›
- Methotrexate ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Acetaminophen, Aspirin, Caffeine ›
- Dextroamphetamine ›
- Naproxen ›
- Lamotrigine ›
- Bendamustine ›
- Quetiapine ›
- Clonazepam ›
- Acyclovir ›
- Buspirone ›
- Duloxetine ›
- Omeprazole ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
- Ciprofloxacin ›
- Acetaminophen, Codeine ›
Showing the 60 most looked-up of 2,823 medications checked with no known interaction — see the full Watercress list.
Watercress References
The 34 references that drive our Watercress monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Leclercq I, Desager JP, Horsmans Y. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress. Clin Pharmacol Ther 1998;64:144-9. PubMed
- Bolton-Smith C, Price RJ, Fenton ST, et al. Compilation of a provisional UK database for the phylloquinone (vitamin K1) content of foods. Br J Nutr 2000;83:389-99.
- Rondelaud, D., Dreyfuss, G., Bouteille, B., and Darde, M. L. Changes in human fasciolosis in a temperate area: about some observations over a 28-year period in central France. Parasitol.Res 2000;86(9):753-757. PubMed
- Sanchez-Sosa, S., Rojas-Ortega, S., Reed-San Roman, G., and Torres-Santana, M. A. [Massive hepatobiliary fascioliasis]. Rev Gastroenterol.Mex. 2000;65(4):179-183.
- van Daele, P. L., Madretsma, G. S., and van Agtmael, M. A. [Stomach ache and fever after consumption of watercress in Turkey: fascioliasis]. Ned.Tijdschr.Geneeskd. 9-29-2001;145(39):1896-1899.
- Cosme, A., Ojeda, E., Cilla, G., Torrado, J., Alzate, L., Beristain, X., Orive, V., and Arenas, J. [Fasciola hepatica. study of a series of 37 patients]. Gastroenterol.Hepatol. 2001;24(8):375-380.
- Martinez-Bebert, K., Rodriguez-Baez, R., Pila-Perez, R., Pila-Pelaez, R., and Tamakloe, K. [Hepatic hematoma caused by fascioliasis]. Gac.Med Mex. 2002;138(3):271-274.
- Dreyfuss, G., Vignoles, P., Abrous, M., and Rondelaud, D. Unusual snail species involved in the transmission of Fasciola hepatica in watercress beds in central France. Parasite 2002;9(2):113-120.
- Christmann, M., Henrich, R., Mayer, G., and Ell, C. [Infection with fasciola hepatica causing elevated liver-enzyme results and eosinophilia - serologic and endoscopic diagnosis and therapy]. Z.Gastroenterol. 2002;40(9):801-806.
- Cosme, A., Ojeda, E., Poch, M., Bujanda, L., Castiella, A., and Fernandez, J. Sonographic findings of hepatic lesions in human fascioliasis. J Clin Ultrasound 2003;31(7):358-363. PubMed
- Sapunar, J., Latorre, R., Guerra, M., and Defilippi, C. [Clinical considerations on 2 cases of hepatic fascioliasis. Importance of the imaging examinations]. Bol.Chil.Parasitol. 1992;47(3-4):70-76.
- de Gorgolas, M., Torres, R., Verdejo, C., Garay, J., Robledo, A., Ponte, M. C., and Fernandez Guerrero, M. L. [Fasciola hepatica infestation. Biopathology and new diagnostic and therapeutic aspects]. Enferm.Infecc.Microbiol.Clin 1992;10(9):514-519.
- Carrada-Bravo, T. [Fascioliasis: diagnosis, epidemiology and treatment]. Rev Gastroenterol.Mex. 2003;68(2):135-142.
- Yilmaz, H. and Godekmerdan, A. Human fasciolosis in Van province, Turkey. Acta Trop. 2004;92(2):161-162.
- Dobrucali, A., Yigitbasi, R., Erzin, Y., Sunamak, O., Polat, E., and Yakar, H. Fasciola hepatica infestation as a very rare cause of extrahepatic cholestasis. World J Gastroenterol. 10-15-2004;10(20):3076-3077. PubMed
- Alvarez-Chacon, R., Garcia-Rosales, J. J., de la Cruz-Otero MC, Wong-Chio, M., Cabrera-Bravo, M., Gomez-Gomez, J. V., and Gamez-Aranda, V. [Fascioliasis in children. A study of 10 cases]. Bol.Med Hosp.Infant Mex. 1992;49(6):365-371.
- Mailles, A., Capek, I., Ajana, F., Schepens, C., Ilef, D., and Vaillant, V. Commercial watercress as an emerging source of fascioliasis in Northern France in 2002: results from an outbreak investigation. Epidemiol.Infect. 2006;134(5):942-945.
- Cruz, Lopez O., Adan, Pimentel A., Tamariz Cruz, O. J., Munoz, Lopez A., Cruz Lopez, M. C., Cruz Lopez, M. E., and Munoz, Lopez S. [Hepatic fasciolasis diagnosed in state phase]. Rev Gastroenterol Mex. 2006;71(1):59-62.
- el Shazly, A. M., Handousa, A. E., Youssef, M. E., Rizk, H., and Hamouda, M. M. Human fascioliasis: a parasitic health problem in Dakahlia Governorate, Egypt. J Egypt.Soc Parasitol. 1991;21(2):553-559.
- Cosme, A., Alzate, L., Orive, V., Recasens, M., Torrado, J., Ruiz, I., and Arenas, J. [Laparoscopic findings in liver fascioliasis. Study of 13 cases]. Rev Esp.Enferm.Dig. 1990;78(6):359-362.
- Diaz, J., Pina, B., Lastre, M., Rivera, L., and Perez, O. [Epidemic human fascioliasis. Cuba 1983. VI. Clinical study of 40 children in the Hospital Provincial of Sagua la Grande]. G.E.N. 1990;44(4):385-388.
- Borie, C., Corona, S., Garin, A., Olea, P., Salcedo, M., Perez, C., and Apt, W. [A family outbreak of acute hepatic fascioliasis]. Rev Med Chil. 1990;118(1):67-72.
- Diamond, S. P., Wiener, S. G., and Marks, J. G., Jr. Allergic contact dermatitis to nasturtium. Dermatol.Clin. 1990;8(1):77-80. DOI
- Delasalle, P., Beytout, J., Cambon, M., and Bommelaer, G. [Distomatosis: diagnosis and treatment]. Rev Prat. 1-21-1990;40(3):230-236.
- Rivera, J. V. and Bermudez, R. H. Radionuclide imaging of the liver in human fascioliasis. Clin Nucl.Med 1984;9(8):450-453. PubMed
- Croese, J., Chapman, G., and Gallagher, N. D. Evolution of fascioliasis after eating wild watercress. Aust.N.Z.J.Med. 1982;12(5):525-527. PubMed
- Bendezu, P., Frame, A., and Hillyer, G. V. Human fascioliasis in Corozal, Puerto Rico. J Parasitol. 1982;68(2):297-299. DOI
- Derrick, E. and Darley, C. Contact dermatitis to nasturtium. Br.J Dermatol 1997;136(2):290-291. PubMed
- Narain, K., Biswas, D., Rajguru, S. K., and Mahanta, J. Human distomatosis due to Fasciola hepatica infection in Assam, India. J Commun.Dis 1997;29(2):161-165.
- Brinker, F. Herb Contraindications and Drug Interactions. 1998;2nd edition.
- Gruenwald, J. PDR for Herbal Medicines. 1998;1st ed.
- Clemente M, Miguel MD, Felipe KB, et al. Effect of watercress extract supplementation on lipid profile and oxidative stress markers in overweight people with physical disability: A randomized, double-blind, and placebo-controlled trial. Phytother Res. 202 PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Cefaclor Is Linked to Lower Levels of 7 Nutrients
Natural Medicines records Cefaclor as a medicine that can lower these. This is not an interaction with Watercress — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Cefaclor nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Watercress and Cefaclor Together: Common Questions
Is it safe to take Watercress with Cefaclor?
Do Watercress and Cefaclor have any of the same side effects?
Should I take Watercress and Cefaclor at the same time of day?
How was the Watercress and Cefaclor combination checked?
Does Watercress interact with any other medications?
Does Cefaclor interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.