Drug & supplement interaction

White Lily + Progesterone

Progesterone brand name: Milprosa.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between White Lily and Progesterone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

White Lily and Progesterone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Progesterone and White Lily in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for White Lily at all — not against Progesterone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

White Lily safety at a glance

White Lily overall Use caution Mostly used topically with limited safety data; skin reactions are possible.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Progesterone and White Lily? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Progesterone’s Own FDA Label Lists

This is not an interaction — none of it involves White Lily. These are the most notable effects listed in the ADVERSE REACTIONS section of Progesterone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Chest pain Worth acting on
  • Low mood Worth acting on
  • Breast tenderness
  • Flushing
  • Bloating or gas
  • Sweating
  • Joint pain
  • Constipation
  • Swelling
  • Dizziness mentioned in 4.2% of FDA reports for Progesterone

Showing the 10 most notable of 15 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Progesterone. Read the label on DailyMed › Where a percentage is shown, it is the share of 22,512 voluntary FDA FAERS reports for Progesterone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. White Lily’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no White Lily side to compare — that is a limit of the record, not a statement that White Lily has no side effects.

Overlapping uses

What Progesterone Is Prescribed For, and What White Lily Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Progesterone is a prescription medicine with approved uses on its FDA label. White Lily is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Progesterone is prescribed for: Progesterone capsules (including Prometrium) are used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking estrogen, and to treat secondary amenorrhea (missed periods not caused by pregnancy). Progesterone injection is indicated for amenorrhea and abnormal uterine bleeding caused by a hormonal imbalance. Crinone vaginal gel is used as part of Assisted Reproductive Technology (ART) for progesterone supplementation or replacement, and Crinone 4% is also indicated for secondary amenorrhea. Vaginal inserts — including Endometrin and other progesterone vaginal insert products — are used to support embryo implantation and early pregnancy as part of an ART treatment program for infertile women.

White Lily has been studied for:

  • Bleeding studied, not established White Lily has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    White Lily for bleeding

    Although there has been interest in using oral white lily for bleeding, there is insufficient reliable information about the clinical effects of white lily for this condition.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Progesterone on your own; if you are taking White Lily for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About White Lily or Progesterone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers White Lily or Progesterone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Progesterone

This page covers White Lily only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Progesterone page lists 126 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 91 moderate · 33 minor.

From our pharmacist’s overview on the Progesterone page

“Many people take progesterone (Milprosa) to support a pregnancy during fertility treatment or as part of hormone therapy, which is exactly when St. John's wort for mood or a morning glass of grapefruit juice can feel harmless.”

Reviewed by 2 · Jul 18, 2026

Open the Progesterone interaction page

One more smart check

Taking White Lily as Part of a Dietary Supplement Product? Check It for Interactions

We hold 45 real supplement products containing White Lily, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Lily. Even though White Lily itself has no known interaction with Progesterone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where White Lily and Progesterone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement White Lily
Steady interest

#981 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Progesterone
Top 25%

#565 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. White Lily is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Lily reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The White Lily and Progesterone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About White Lily

What is White Lily?

  • Skin soothing and minor wounds
  • Burns and skin irritation
  • Cosmetic and anti-aging skin care
  • Corns and calluses (traditional)
  • Inflamed or chapped skin

White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor skin problems and soothing. Good-quality human studies are very limited, so most of its reputation comes from folk use rather than strong science. Talk with a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Lilium candidum · Liliaceae · Bulbs and flowers (sometimes prepared as oil or ointment) · Topical oils, ointments, infused oil, creams, and traditional poultices

An interaction check asks whether these two react with each other — it does not ask whether White Lily is a good idea for someone in your situation. Here is what our White Lily record says about it on its own.

White Lily: dosing

There is no established standardized dose for White Lily. It is sold mostly as topical oils, creams, and ointments, and amounts vary widely between products.If you use a commercial product, follow the directions on the label and apply only to the skin unless a professional tells you otherwise.

From our White Lily monograph — the full record covers uses, side effects and every documented interaction.

Read the full White Lily monograph & all interactions
Medication

About Progesterone

What Is Progesterone Used For?

Brand name: Milprosa

Progesterone capsules (including Prometrium) are used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking estrogen, and to treat secondary amenorrhea (missed periods not caused by pregnancy).

Progesterone injection is indicated for amenorrhea and abnormal uterine bleeding caused by a hormonal imbalance. Crinone vaginal gel is used as part of Assisted Reproductive Technology (ART) for progesterone supplementation or replacement, and Crinone 4% is also indicated for secondary amenorrhea. Vaginal inserts — including Endometrin and other progesterone vaginal insert products — are used to support embryo implantation and early pregnancy as part of an ART treatment program for infertile women.

Most-Reported Side Effects for Progesterone

From FAERS, the FDA’s public side-effect reporting system (22,803 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 2,094 reports
Fatigue 1,795 reports
Nausea 1,475 reports
Rash 984 reports
Dizziness 941 reports
See full Progesterone drug information
Keep checking

Other Drugs & White Lily

Browse every other medication we’ve checked against White Lily — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked White Lily against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full White Lily list.

See the full White Lily interactions page
See every supplement checked against Progesterone, ranked by severity
Evidence & sources

White Lily References

The 2 sources that drive our White Lily monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. White Lily is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Poisonous Plants — MedlinePlus (U.S. National Library of Medicine) Source
  2. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking White Lily and Progesterone Together: Common Questions

Is it safe to take White Lily with Progesterone?
We do not list a known interaction between White Lily and Progesterone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are White Lily and Progesterone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for White Lily in each. That is a conversation for your prescriber, especially if Progesterone is being adjusted to a target.
Does Progesterone interact with any supplements?
Yes. Progesterone has documented interactions with 126 supplements in our database — White Lily is not one of them. The Progesterone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

White Lily monograph Uses, safety profile, and every drug interaction in one place Progesterone drug information The full plain-English guide to this medication Progesterone supplement interactions Every supplement checked against Progesterone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Progesterone and White Lily?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.