Drug & supplement interaction

Wild Cherry + Tioconazole

Tioconazole brand name: Vagistat.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Wild Cherry and Tioconazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Wild Cherry and Tioconazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tioconazole and Wild Cherry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wild Cherry safety at a glance

Wild Cherry overall Use caution Generally considered safe in small amounts in commercial cough products, but the plant contains cyanide-forming compounds and should not be used in large amount...
Pregnancy Likely Unsafe When used orally because prunasin is potentially teratogenic. Read the full pregnancy detail
Breastfeeding Avoid Safety has not been established, so avoid use while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tioconazole and Wild Cherry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tioconazole

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tioconazole is filed under 2 classifications — antifungals, oral drugs. Wild Cherry has documented interactions with 1 drug class — the most serious being cytochrome p450 3a4 (cyp3a4) substrates (moderate) — and none of Tioconazole’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Wild Cherry Does Interact With Other Medications

Wild Cherry has 643 moderate known drug interactions in our database — Tioconazole isn’t one of them. If you take anything else, check it against the full list below.

Moderate 643 No known interaction 2,187 (incl. Tioconazole)
Taking anything else?

Check Another of Your Medications Against Wild Cherry

Covers the 2,830 medications we’ve checked against Wild Cherry. Pick one to open its full report.

What to actually watch for

What Wild Cherry Itself Has Been Linked To

This is not an interaction — nothing below involves Tioconazole. It is the side-effect record for Wild Cherry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Wild Cherry, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A slow heartbeat / Hallucinations / Confusion / Shortness of breath Worth acting on Additional detail

    “Orally, large amounts of wild cherry can lead to cyanide toxicity, which can be fatal (18,41565). A case of accidental poisoning has been reported for a 56-year old women who consumed approximately 300 grams of wild cherries that had been steeped in alcohol the evening before symptom onset.”

    Wild Cherry · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 41565. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed
  • Blurred vision / Numbness or tingling / Anxiety or restlessness / Vomiting / Headache / Nausea Additional detail

    Recorded for Wild Cherry in the same Natural Medicines adverse-effect record shown under A slow heartbeat / Hallucinations / Confusion / Shortness of breath above.

Everything above comes from the Natural Medicines adverse-effect record for Wild Cherry — expand a row for the licensed statement it rests on. We haven’t matched Tioconazole to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tioconazole.

Special populations

Wild Cherry in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally because prunasin is potentially teratogenic.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tioconazole

This page covers Wild Cherry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tioconazole page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Tioconazole page

“Activated charcoal carries the only major rating among the 20 supplements flagged for tioconazole (Vagistat), and it is the pairing to sort out first. Charcoal binds many medications, lowering the amount that reaches the body, and this can happen regardless of how a drug is given.”

Reviewed by 2 · Jul 18, 2026

Open the Tioconazole interaction page

One more smart check

Taking Wild Cherry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 439 real supplement products containing Wild Cherry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Cherry. Even though Wild Cherry itself has no known interaction with Tioconazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Cherry and Tioconazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Cherry
Top 25%

#300 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tioconazole
Steady interest

#2,454 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wild Cherry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Wild Cherry and Tioconazole records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wild Cherry

What is Wild Cherry?

Wild Cherry
  • Cough
  • Bronchitis and respiratory irritation
  • Sore throat
  • Digestive upset and diarrhea
  • Flavoring agent

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and seeds naturally contain cyanide-producing compounds, so it should be used only in properly prepared products and avoided in large amounts. Talk with a pharmacist or doctor before using it, especially during pregnancy or for children.

Prunus serotina · Rosaceae · Bark (inner and stem bark), and sometimes fruit and leaves · Syrup, cough lozenges, tea, tincture, dried bark extract

An interaction check asks whether these two react with each other — it does not ask whether Wild Cherry is a good idea for someone in your situation. Here is what our Wild Cherry record says about it on its own.

Wild Cherry: dosing

There is no well-established standardized dose for wild cherry. Amounts vary widely between different syrups, lozenges, teas, and tinctures.The safest approach is to follow the directions on the product label and not to exceed them. Avoid making concentrated homemade preparations from the bark, leaves, or pits.

From our Wild Cherry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wild Cherry monograph & all interactions
Medication

About Tioconazole

Most-Reported Side Effects for Tioconazole

From FAERS, the FDA’s public side-effect reporting system (1,541 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Vulvovaginal burning sensation 526 reports
Vulvovaginal swelling 295 reports
Vulvovaginal pain 229 reports
Vulvovaginal pruritus 197 reports
Vulvovaginal discomfort 161 reports
Keep checking

Other Drugs & Wild Cherry

Browse every other medication we’ve checked against Wild Cherry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
643Moderate
0Minor
2,186No known interaction
643 Moderate 2,186 No interaction
Moderate

643 interactions

Showing 60 of 643 moderate interactions — see all 643 on the Wild Cherry page.

No interaction 2,186 drugs checked — show the list

We also checked Wild Cherry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,186 medications checked with no known interaction — see the full Wild Cherry list.

See the full Wild Cherry interactions page
See every supplement checked against Tioconazole, ranked by severity
Evidence & sources

Wild Cherry References

The 4 references that drive our Wild Cherry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wild Cherry and Tioconazole Together: Common Questions

Is it safe to take Wild Cherry with Tioconazole?
We do not list a known interaction between Wild Cherry and Tioconazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Wild Cherry and Tioconazole combination checked?
Interactions in our licensed database are recorded against drug classes. Tioconazole is filed under 2 classifications, and Wild Cherry has documented interactions with 1 drug class — none of Tioconazole's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Wild Cherry interact with any other medications?
Yes. Wild Cherry has 643 documented drug interactions in our database — Tioconazole is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tioconazole interact with any supplements?
Yes. Tioconazole has documented interactions with 20 supplements in our database — Wild Cherry is not one of them. The Tioconazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wild Cherry monograph Uses, safety profile, and every drug interaction in one place Tioconazole supplement interactions Every supplement checked against Tioconazole, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tioconazole and Wild Cherry?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.